Promise of Physiological Profiling to Prevent Stroke in People of African Ancestry: Prototyping Ghana

Owolabi M, Akarolo-Anthony S, Akinyemi R, Arnett D, Gebregziabher M, Jenkins C, et al. The burden of stroke in Africa: a glance at the present and a glimpse into the future. Cardiovasc J Afr. 2015;26(2 Suppl 1):S27-38.

PubMed  PubMed Central  Article  Google Scholar 

Ovbiagele B, Goldstein LB, Higashida RT, Howard VJ, Johnston SC, Khavjou OA, et al. American Heart Association Advocacy Coordinating Committee and Stroke Council. Forecasting the future of stroke in the United States: a policy statement from the American Heart Association and American Stroke Association. Stroke. 2013;44(8):2361–75. https://doi.org/10.1161/STR.0b013e31829734f2.

Article  PubMed  Google Scholar 

Howard VJ, Kleindorfer DO, Judd SE, McClure LA, Safford MM, Rhodes JD, et al. Disparities in stroke incidence contributing to disparities in stroke mortality. Ann Neurol. 2011;69:619–27. https://doi.org/10.1002/ana.22385. Compared to non-Hispanic Whites, African Americans (AA) have disproportionately higher stroke incidence and mortality rates largely due to differences in hypertension burden.

Article  PubMed  PubMed Central  Google Scholar 

Kissela B, Schneider A, Kleindorfer D, Khoury J, Miller R, Alwell K, et al. Stroke in a biracial population: the excess burden of stroke among blacks. Stroke. 2004;35:426–31.

PubMed  Article  Google Scholar 

Rosamond WD, Folsom AR, Chambless LE, Wang CH, McGovern PG, Howard G, et al. Stroke incidence and survival among middle-aged adults: 9-year follow-up of the Atherosclerosis Risk in Communities (ARIC) cohort. Stroke. 1999;30:736–43.

CAS  PubMed  Article  Google Scholar 

Walker R, Whiting D, Unwin N, Mugusi F, Swai M. Stroke incidence in rural and urban Tanzania: a prospective, community-based study. Lancet Neurol. 2010;9:786–92.

PubMed  Article  Google Scholar 

Ezejimofor MC, Uthman OA, Maduka O, et al. Stroke survivors in Nigeria: a door-to-door prevalence survey from the Niger Delta region. J Neurol Sci. 2017;15(372):262–9.

Article  Google Scholar 

Sarfo FS, Awuah DO, Nkyi C, Akassi J, Opare-Sem OK, Ovbiagele B. Recent patterns and predictors of neurological mortality among hospitalized patients in Central Ghana. J Neurol Sci. 2016;363:217–24.

PubMed  Article  Google Scholar 

Sarfo FS, Akassi J, Awuah D, Adamu S, Nkyi C, Owolabi M, et al. Trends in stroke admission and mortality rates from 1983 to 2013 in central Ghana. J Neurol Sci. 2015;357(1–2):240–5.

PubMed  Article  Google Scholar 

Sarfo FS, Akassi J, Ofori E, Ovbiagele B. Long-term determinants of death after stroke in Ghana: analysis by stroke types and subtypes. J Stroke Cerebrovasc Dis. 2022;31(9): 106639.

PubMed  Article  Google Scholar 

Feigin VL, Roth GA, Naghavi M. Global burden of stroke and risk factors in 188 countries, during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2016;15:913–24.

Article  Google Scholar 

Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Blaha MJ, et al. Heart disease and stroke statistics—2014 update: a report from the american heart association. Circulation. 2014;129(3):e28–292.

PubMed  Google Scholar 

O’Donnell MJ, Xavier D, Liu L, et al. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet. 2010;376:112–23.

PubMed  Article  Google Scholar 

Howard G, Prineas R, Moy C, Cushman M, Kellum M, Temple E, et al. Racial and geographic differences in awareness, treatment and control of hypertension: the Reasons for Geographic and Racial Differences in Stroke study. Stroke. 2006;37:1171–8.

PubMed  Article  Google Scholar 

Owolabi MO, Sarfo FS, Akinyemi R, Gebregziabher M, Akpa O, Akpalu A, et al. Dominant modifiable risk factors for stroke in Ghana and Nigeria (SIREN): a case-control study. Lancet Glob Health. 2018;6(4):e436–46.

PubMed  PubMed Central  Article  Google Scholar 

Kaze AD, Schutte AE, Erqou S, Kengne AP, Echouffo-Tcheugui JB. Prevalence of hypertension in older people in Africa: a systematic review and meta-analysis. J Hypertens. 2017;35:1345–52.

CAS  PubMed  Article  Google Scholar 

KuateDefo B, Mbanya JC, Tardif JC, et al. Diagnosis, prevalence, awareness, treatment, prevention, and control of hypertension in Cameroon: protocol for a systematic review and meta-analysis of clinic-based and community-based studies. JMIR Res Protoc. 2017;6:e102.

Article  Google Scholar 

Opie LH, Seedat YK. Hypertension in sub-Saharan African populations. Circulation. 2005;112(23):3562–8.

PubMed  Article  Google Scholar 

Towfighi A, Markovic D, Ovbiagele B. Consistency of blood pressure control after ischemic stroke: prevalence and prognosis. Stroke J Cereb Circ. 2014;45:1313–7.

Article  Google Scholar 

Sacco RL, Boden-Albala B, Gan R, et al. Stroke incidence among white, black, and Hispanic residents of an urban community: the Northern Manhattan Stroke Study. Am J Epidemiol. 1998;147:259–68.

CAS  PubMed  Article  Google Scholar 

Sarfo FS, Mobula LM, Plange-Rhule J, Ansong D, Ofori-Adjei D. Incident stroke among Ghanaians with hypertension and diabetes: a multicenter, prospective cohort study. J Neurol Sci. 2018;395:8–16.

PubMed  PubMed Central  Article  Google Scholar 

Ovbiagele B, Ernstrom K, Markovic D, Raman R. Trends in antihypertensive drug prescription patterns among ambulatory stroke patients in the United States, 2000–2009. J Stroke Cerebrovasc Dis Off J Natl Stroke Assoc. 2013;22:e568–75.

Article  Google Scholar 

Carey RM, Calhoun DA, Bakris GL, Brook RD, Daugherty SL, Dennison-Himmelfarb CR, et al. Resistant hypertension: detection, evaluation, and management. A scientific statement from the American Heart Association. Hypertens. 2018;72:e53–90. This study reported the burden of resistant hypertension among Americans and identified its risk factors.

CAS  Article  Google Scholar 

Daugherty SL, Powers JD, Magid DJ, Tavel HM, Masoudi FA, Margolis KL, et al. Incidence and prognosis of resistant hypertension in hypertensive patients. Circ. 2012;125:1635–42.

Article  Google Scholar 

Cuspidi C, Macca G, Sampieri L, Michev I, Salerno M, Fusi V, et al. High prevalence of cardiac and extracardiac target organ damage in refractory hypertension. J Hypertens. 2001;19:2063–70.

CAS  PubMed  Article  Google Scholar 

Carey RM, Sakhuja S, Calhoun DA, Whelton PK, Munter P. Prevalence of apparent treatment resistant hypertension in the United States. Comparison of the 2008 and 2018 American Heart Association Scientific statements on resistant hypertension. Hypertens. 2019;73:424–31.

CAS  Article  Google Scholar 

Batuman J. Salt and hypertension: an evolutionary perspective. J Hypertens. 2012;1:e106.

Article  Google Scholar 

Grim CE, Robinson M. Salt, slavery and survival-hypertension in African diaspora. Epidemiol. 2003;14:120–2.

Article  Google Scholar 

Jones ES, Spence JD, Mcintyre AD, Nondi J, Gogo K, Akintunde A, et al. High frequency of variants of candidate genes in black Africans with low renin-resistant hypertension. Am J Hypertens. 2017;30:478–83.

CAS  PubMed  Google Scholar 

Bochud M, Staessen JA, Maillard M, Mazeko MJ, Kuznetsova T, Woodiwiss A, et al. Ethnic differences in proximal and distal tubular sodium reabsorption are heritable in black and white populations. J Hypertens. 2009;27:606–12.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Tu W, Eckert GJ, Hannon TS, Liu H, Pratt LM, Wagner MA, et al. Racial differences in sensitivity of blood pressure to aldosterone. Hypertension. 2014;63:1212–8.

CAS  PubMed  Article  Google Scholar 

Thomas G, Xie D, Chen HY, Anderson AH, Appel LJ, Bodana S, et al. CRIC Study Investigators. Prevalence and prognostic significance of apparent treatment resistant hypertension in chronic kidney disease: report from the Chronic Renal Insufficiency Cohort Study. Hypertens. 2016;67:387–96.

CAS  Article  Google Scholar 

Smith SM, Gong Y, Handberg E, Messerli FH, Bakris GL, Ahmed A, et al. Predictors and outcomes of resistant hypertension among patients with coronary artery disease and hypertension. J Hypertens. 2014;32:635–43.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Smith SM, Huo T, Delia Johnson B, Bittner V, Kelsey SF, Vido Thompson D, et al. Cardiovascular and mortality risk of apparent resistant hypertension in women with suspected myocardial ischemic: a report from the NHLBI-sponsored WISE Study. J Am Heart Assoc. 2014;3:e000660.

PubMed  PubMed Central  Article  Google Scholar 

Bangalore S, Fayyad R, Laskey R, Demicco DA, Deedwania P, Kostis JB, et al. Treating to new targets steering committee and investigators. Prevalence, predictors and outcomes in treatment-resistant hypertension in patients with coronary. Am J Med. 2014;127:71–81.

PubMed  Article  Google Scholar 

Rotin D, Staub O. Nedd4-2 and the regulation of epithelial sodium transport. Front Physiol. 2012;3:212.

PubMed  PubMed Central  Article  Google Scholar 

Laffer CL, Elijovich F, Eckert GJ, Tu W, Pratt JH, Brown NJ. Genetic variation in CYP4A11 and blood pressure response to mineralocorticoid receptor antagonism or ENaC inhibition: an exploratory pilot study in African Americans. J Am Soc Hypertens. 2014;8:475–80.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Michel FS, Norton GR, Majane OHI, et al. Contribution of circulating angiotensinogen concentrations to variations in aldosterone and blood pressure in a group of African ancestry depends on salt intake. Hypertension. 2012;59:62–9.

CAS  PubMed  Article  Google Scholar 

Rayner BL, Spence JD. Hypertension in Blacks: insights from Africa. J Hypertens. 2017;35(2):234–9. This study highlighted that blacks have a greater propensity to salt sensitivity and suppressed plasma renin suggesting a predisposition to sodium retention. Target organ damage is more frequent and blood pressure is more difficult to control.

CAS  PubMed  Article  Google Scholar 

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