AOP-Wiki (2013) AOP Wiki. https://aopwiki.org/aops?utf8=✓&search=breast+cancer&commit=Search&find_by_id=. Accessed 5 Dec 2021

Applanat MP, Buteau-Lozano H, Herve MA, Corpet A (2008) Vascular endothelial growth factor is a target gene for estrogen receptor and contributes to breast cancer progression. In: Li J, Li SA, Mohla S et al (eds) Hormonal Carcinogenesis V. Springer, New York, pp 437–444

Chapter  Google Scholar 

Arrigoni A, Ranzani V, Rossetti G et al (2016) Analysis RNA-seq and noncoding RNA. Methods Mol Biol 1480:125–135. https://doi.org/10.1007/978-1-4939-6380-5_11

CAS  Article  PubMed  Google Scholar 

Bai Z, Gust R (2009) Breast cancer, estrogen receptor and ligands. Arch Pharm (weinheim) 342:133–149. https://doi.org/10.1002/ardp.200800174

CAS  Article  Google Scholar 

Björnström L, Sjöberg M (2005) Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol Endocrinol 19:833–842. https://doi.org/10.1210/me.2004-0486

CAS  Article  PubMed  Google Scholar 

Buisson R, Dion-Côté AM, Coulombe Y et al (2010) Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination. Nat Struct Mol Biol 17:1247–1254. https://doi.org/10.1038/nsmb.1915

CAS  Article  PubMed  PubMed Central  Google Scholar 

Bulun SE, Chen D, Moy I et al (2012) Aromatase, breast cancer and obesity: a complex interaction. Trends Endocrinol Metab 23:83–89. https://doi.org/10.1016/j.tem.2011.10.003

CAS  Article  PubMed  Google Scholar 

Cadet J, Wagner RJ (2013) DNA base damage by reactive oxygen species, oxidizing agents, and UV radiation. Cold Spring Harb Perspect Biol 5:a012559. https://doi.org/10.1101/cshperspect.a012559

CAS  Article  PubMed  PubMed Central  Google Scholar 

Caldon CE (2014) Estrogen signaling and the DNA damage response in hormone dependent breast cancers. Front Oncol. https://doi.org/10.3389/fonc.2014.00106

Article  PubMed  PubMed Central  Google Scholar 

Cantley LC (2002) The phosphoinositide 3-kinase pathway. Science 296:1655–1657. https://doi.org/10.1126/science.296.5573.1655

CAS  Article  PubMed  Google Scholar 

Carpenter RL, Lo H-W (2013) Regulation of apoptosis by HER2 in breast cancer. J Carcinog Mutagen 2013:003. https://doi.org/10.4172/2157-2518.S7-003

CAS  Article  PubMed  PubMed Central  Google Scholar 

Cavalieri E, Frenkel K, Liehr JG et al (2000) Estrogens as endogenous genotoxic agents-DNA adducts and mutations. J Natl Cancer Inst Monogr 27:75–93. https://doi.org/10.1093/oxfordjournals.jncimonographs.a024247

CAS  Article  Google Scholar 

Chan JSK, Tan MJ, Sng MK et al (2017) Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress. Cell Death Dis 8:1–12. https://doi.org/10.1038/cddis.2016.492

CAS  Article  Google Scholar 

Chandel NS, McClintock DS, Feliciano CE et al (2000) Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia. J Biol Chem 275:25130–25138. https://doi.org/10.1074/jbc.M001914200

CAS  Article  PubMed  Google Scholar 

Chen Y, Song Y, Du W et al (2019) Tumor-associated macrophages: an accomplice in solid tumor progression. J Biomed Sci 26:1–13. https://doi.org/10.1186/s12929-019-0568-z

CAS  Article  Google Scholar 

Comito G, Calvani M, Giannoni E et al (2011) HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells. Free Radical Biol Med 51:893–904. https://doi.org/10.1016/j.freeradbiomed.2011.05.042

CAS  Article  Google Scholar 

Dai X, Li T, Bai Z et al (2015) Breast cancer intrinsic subtype classification, clinical use and future trends. Am J Cancer Res 5:2929–2943

CAS  PubMed  PubMed Central  Google Scholar 

Davis JD, Shiaw-Yih L (2011) DNA damage and breast cancer. World J Clin Oncol 2:329–338. https://doi.org/10.5306/wjco.v2.i9.329

Article  PubMed  PubMed Central  Google Scholar 

di Meo S, Reed TT, Venditti P, Victor VM (2016) Role of ROS and RNS sources in physiological and pathological conditions. Oxid Med Cell Longev 2016:1245049. https://doi.org/10.1155/2016/1245049

CAS  Article  PubMed  PubMed Central  Google Scholar 

Doisneau-Sixou SF, Sergio CM, Carroll JS et al (2003) International congress on hormonal steroids and hormones and cancer estrogen and antiestrogen regulation of cell cycle progression in breast cancer cells. Endocr Relat Cancer 10:179–186. https://doi.org/10.1677/erc.0.0100179

CAS  Article  PubMed  Google Scholar 

Finotello F, di Camillo B (2015) Measuring differential gene expression with RNA-seq: Challenges and strategies for data analysis. Brief Funct Genomics 14:130–142. https://doi.org/10.1093/bfgp/elu035

CAS  Article  PubMed  Google Scholar 

Ford KA (2016) Refinement, reduction, and replacement of animal toxicity tests by computational methods. ILAR J 57:226–233. https://doi.org/10.1093/ilar/ilw031

CAS  Article  PubMed  Google Scholar 

Foulkes WD, Smith IE, Reis-Filho JS (2010) Triple-negative breast cancer. N Engl J Med 363:1938–1986. https://doi.org/10.1056/NEJMra1001389

CAS  Article  PubMed  Google Scholar 

Gao N, Jiang BH, Leonard SS et al (2002) p38 signaling-mediated hypoxia-inducible factor 1α and vascular endothelial growth factor induction by Cr(VI) in DU145 human prostate carcinoma cells. J Biol Chem 277:45041–45048. https://doi.org/10.1074/jbc.M202775200

CAS  Article  PubMed  Google Scholar 

Giordano SH (2018) Breast cancer in men. N Engl J Med 378:2311–2320. https://doi.org/10.1056/NEJMra1707939

Article  PubMed  Google Scholar 

Hah N, Danko CG, Core L et al (2011) A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells. Cell 145:622–634. https://doi.org/10.1016/j.cell.2011.03.042

CAS  Article  PubMed  PubMed Central  Google Scholar 

Harari D, Yarden Y (2000) Molecular mechanisms underlying ErbB2/HER2 action in breast cancer. Oncogene 19:6102–6114. https://doi.org/10.1038/sj.onc.1203973

CAS  Article  PubMed  Google Scholar 

Hecht F, Pessoa CF, Gentile LB et al (2016) The role of oxidative stress on breast cancer development and therapy. Tumor Biology 37:4281–4291. https://doi.org/10.1007/s13277-016-4873-9

CAS  Article  PubMed  Google Scholar 

Heinonen H, Nieminen A, Saarela M et al (2008) Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer. BMC Genomics 9:1–12. https://doi.org/10.1186/1471-2164-9-348

CAS  Article  Google Scholar 

Helm JS, Rudel RA (2020) Adverse outcome pathways for ionizing radiation and breast cancer involve direct and indirect DNA damage, oxidative stress, inflammation, genomic instability, and interaction with hormonal regulation of the breast. Arch Toxicol 94:1511–1549. https://doi.org/10.1007/s00204-020-02752-z

CAS  Article  PubMed  PubMed Central  Google Scholar 

Hofstatter EW, Domchek SM, Miron A et al (2011) PALB2 mutations in familial breast and pancreatic cancer. Fam Cancer 10:225–231. https://doi.org/10.1007/s10689-011-9426-1

CAS  Article  PubMed  Google Scholar 

Holen I, Speirs V, Morrissey B, Blyth K (2017) In vivo models in breast cancer research: progress, challenges and future directions. DMM Dis Models Mech 10:359–371

CAS  Article  Google Scholar 

Houthuijzen JM, Jonkers J (2018) Cancer-associated fibroblasts as key regulators of the breast cancer tumor microenvironment. Cancer Metastasis Rev 37:577–597. https://doi.org/10.1007/s10555-018-9768-3

CAS  Article  PubMed  Google Scholar 

Iorio M, v., Ferracin M, Liu CG, et al (2005) MicroRNA gene expression deregulation in human breast cancer. Can Res 65:7065–7070. https://doi.org/10.1158/0008-5472.CAN-05-1783

CAS  Article  Google Scholar 

Iqbal N, Iqbal N (2014) Human epidermal growth factor receptor 2 (HER2) in cancers: overexpression and therapeutic implications. Mol Biol Int 2014:852748. https://doi.org/10.1155/2014/852748

CAS  Article  PubMed  PubMed Central  Google Scholar 

Jha N, Ryu JJ, Choi EH, Kaushik NK (2017) Generation and role of reactive oxygen and nitrogen species induced by plasma, lasers, chemical agents, and other systems in dentistry. Oxid Med Cell Longev 2017:7542540. https://doi.org/10.1155/2017/7542540

CAS  Article  PubMed  PubMed Central  Google Scholar 

Kamel D, Gray C, Walia JS, Kumar V (2018) PARP inhibitor drugs in the treatment of breast, ovarian, prostate and pancreatic cancers: an update of clinical trials. Curr Drug Targets 19:21–37. https://doi.org/10.2174/1389450118666170711151518

CAS  Article  PubMed  Google Scholar 

Klement GL, Goukassian D, Hlatky L et al (2012) Cancer therapy targeting the HER2-PI3K pathway: potential impact on the heart. Front Pharmacol 3:113. https://doi.org/10.3389/fphar.2012.00113

Article  PubMed  PubMed Central  Google Scholar 

Kumar P, Aggarwal R (2016) An overview of triple-negative breast cancer. Arch Gynecol Obstet 293:247–269. https://doi.org/10.1007/s00404-015-3859-y