Adeyemo OM, Sirén AL (1992) Cardio-respiratory changes and mortality in the conscious rat induced by (+)- and (±)-anatoxin-a. Toxicon 30:899–905. https://doi.org/10.1016/0041-0101(92)90388-L
CAS Article PubMed Google Scholar
Alosman M, Cao L, Massey IY, Yang F (2020) The lethal effects and determinants of microcystin-LR on heart: a mini review. Toxin Rev 40:517–526. https://doi.org/10.1080/15569543.2019.1711417
Atencio L, Moreno I, Jos A, Pichardo S, Moyano R, Blanco A, Cameán AM (2008a) Dose-dependent antioxidant responses and pathological changes in tenca (Tinca tinca) after acute oral exposure to Microcystis under laboratory conditions. Toxicon 52:1–12. https://doi.org/10.1016/j.toxicon.2008.05.009
CAS Article PubMed Google Scholar
Atencio L, Moreno I, Prieto AI, Moyano R, Molina AM, Cameán AM (2008b) Acute effects of microcystins MC-LR and MC-RR on acid and alkaline phosphatase activities and pathological changes in intraperitoneally exposed tilapia fish (Oreochromis sp.). Toxicol Pathol 36:449–458. https://doi.org/10.1177/0192623308315356
Atencio L, Moreno I, Jos Á, Prieto AI, Moyano R, Blanco A, Cameán AM (2009) Effects of dietary selenium on the oxidative stress and pathological changes in tilapia (Oreochromis niloticus) exposed to a microcystin-producing cyanobacterial water bloom. Toxicon 53:269–282. https://doi.org/10.1016/j.toxicon.2008.11.011
CAS Article PubMed Google Scholar
Azevedo SMFO, Carmichael WW, Jochimsen EM, Rinehart KL, Lau S, Shaw GR, Eaglesham GK (2002) Human intoxication by microcystins during renal dialysis treatment in Caruaru-Brazil. Toxicology 181–182:441–446. https://doi.org/10.1016/S0300-483X(02)00491-2
Backer LC, Miller M (2016) Sentinel animals in a one health approach to harmful cyanobacterial and algal blooms. Vet Sci 3:8. https://doi.org/10.3390/vetsci3020008
Article PubMed Central Google Scholar
Bagu JR, Sykes BD, Craig MM, Holmes CFB (1997) A molecular basis for different interactions of marine toxins with protein phosphatase-1: molecular models for bound motuporin, microcystins, okadaic acid, and calyculin A. J Biol Chem 272:5087–5097. https://doi.org/10.1074/jbc.272.8.5087
CAS Article PubMed Google Scholar
Ballot A, Bernard C, Fastner J (2017) Saxitoxin and analogues. In: Meriluoto J, Spoof L, Codd GA (eds) Handbook of cyanobacterial monitoring and cyanotoxin analysis. Wiley, Chichester, pp 148–154
Basu A, Kozikowski AP, Lazo JS (1992) Structural requirements of lyngbyatoxin A for activation and downregulation of protein kinase C. Biochemistry 31:3824–3830. https://doi.org/10.1021/bi00130a013
CAS Article PubMed Google Scholar
Batista T, de Sousa G, Suput JS, Rahmani R, Šuput D (2003) Microcystin-LR causes the collapse of actin filaments in primary human hepatocytes. Aquat Toxicol 65:85–91. https://doi.org/10.1016/s0166-445x(03)00108-5
CAS Article PubMed Google Scholar
Beasley VR, Lovell RA, Holmes KR, Walcott HE, Schaeffer DJ, Hoffmann WE, Carmichael WW (2000) Microcystin-LR decreases hepatic and renal perfusion, and causes circulatory shock, severe hypoglycemia, and terminal hyperkalemia in intravascularly dosed swine. J Toxicol Environ Health Part A 61:281–303. https://doi.org/10.1080/00984100050136599
Benton BJ, Rivera VR, Hewetson JF, Chang FCT (1994) Reversal of saxitoxin-induced cardiorespiratory failure by a burro-raised α-STX antibody and oxygen therapy. Toxicol Appl Pharmacol 124:39–51. https://doi.org/10.1006/taap.1994.1006
CAS Article PubMed Google Scholar
Bernard C, Harvey M, Briand JF, BiréR KS, Fontaine JJ (2003) Toxicological comparison of diverse Cylindrospermopsis raciborskii strains: evidence of liver damage caused by a French C. raciborskii strain. Environ Toxicol 18:176–186. https://doi.org/10.1002/tox.10112
CAS Article PubMed Google Scholar
Best JH, Eddy FB, Codd GA (2001) Effects of purified microcystin-LR and cell extracts of Microcystis strains PCC 7813 and CYA 43 on cardiac function in brown trout (Salmo trutta) alevins. Fish Physiol Biochem 24:171–178. https://doi.org/10.1023/A:1014081827372
Bhardwaj S, Gupta D (2012) Study of acute, Sub acute and chronic toxicity test. Int J Cur Biomed Phar Res 2:103–129
Bláha L, Babica P, Maršálek B (2009) Toxins produced in cyanobacterial water blooms–toxicity and risks. Interdiscip Toxicol 2:36–41. https://doi.org/10.2478/v10102-009-0006-2
Article PubMed PubMed Central Google Scholar
Bláhová L, Babica P, Adamovský O, Kohoutek J, Maršálek B, Bláha L (2008) Analyses of cyanobacterial toxins (microcystins, cylindrospermopsin) in the reservoirs of the Czech Republic and evaluation of health risks. Environ Chem Lett 6:223–227. https://doi.org/10.1007/s10311-007-0126-x
Bouaïcha N, Miles CO, Beach DG, Labidi Z, Djabri A, Benayache NY, Nguyen-Quang T (2019) Structural diversity, characterization and toxicology of microcystins. Toxins 11:714. https://doi.org/10.3390/toxins11120714
CAS Article PubMed Central Google Scholar
Bownik A, Pawlik-Skowrońska B (2019) Early indicators of behavioral and physiological disturbances in Daphnia magna (Cladocera) induced by cyanobacterial neurotoxin anatoxin-a. Sci Total Environ 695:133913. https://doi.org/10.1016/j.scitotenv.2019.133913
CAS Article PubMed Google Scholar
Brown A, Foss A, Miller MA, Gibson Q (2018) Detection of cyanotoxins (microcystins/nodularins) in livers from estuarine and coastal bottlenose dolphins (Tursiops truncatus) from Northeast Florida. Harmful Algae 76:22–34. https://doi.org/10.1016/j.hal.2018.04.011
CAS Article PubMed Google Scholar
Bruno M, Ploux O, Metcalf JS, Mejean A, Pawlik-Skowronska B, Furey A (2017) Anatoxin-a, homoanatoxin-a, and natural analogues. In: Meriluoto J, Spoof L, Codd GA (eds) Handbook of cyanobacterial monitoring and cyanotoxin analysis. Wiley, Chichester, pp 138–147
Buratti FM, Manganelli M, Vichi S, Stefanelli M, Scardala S, Testai E, Funari E (2017) Cyanotoxins: producing organisms, occurrence, toxicity, mechanism of action and human health toxicological risk evaluation. Arch Toxicol 91:1049–1130. https://doi.org/10.1007/s00204-016-1913-6
CAS Article PubMed Google Scholar
Caban-Holt A, Mattingly M, Cooper G, Schmitt FA (2005) Neurodegenerative memory disorders: a potential role of environmental toxins. Neurol Clin 23:485–521. https://doi.org/10.1016/j.ncl.2004.12.005
Campos A, Vasconcelos V (2010) Molecular mechanisms of microcystin toxicity in animal cells. Int J Mol Sci 11:268–287. https://doi.org/10.3390/ijms11010268
CAS Article PubMed PubMed Central Google Scholar
Cao L, Huang F, Massey IY, Wen C, Zheng S, Xu S, Yang F (2019a) Effects of microcystin-LR on the microstructure and inflammation-related factors of jejunum in mice. Toxins 11:482. https://doi.org/10.3390/toxins11090482
CAS Article PubMed Central Google Scholar
Cao L, Massey IY, Feng H, Yang F (2019b) A review of cardiovascular toxicity of microcystins. Toxins 11:507. https://doi.org/10.3390/toxins11090507
CAS Article PubMed Central Google Scholar
Carbis CR, Rawlin GT, Mitchell GF, Anderson JW, McCauley I (1996) The histopathology of carp, Cyprinus carpio L., exposed to microcystins by gavage, immersion and intraperitoneal administration. J Fish Dis 19:199–207. https://doi.org/10.1111/j.1365-2761.1996.tb00126.x
Cardona T, Sánchez-Baracaldo P, Rutherford AW, Larkum AW (2018) Early Archaean origin of photosystem II. Geobiology 17:127–150. https://doi.org/10.1111/gbi.12322
CAS Article PubMed PubMed Central Google Scholar
Chang FCT, Benton BJ, Lenz RA, Capacio BR (1993) Central and peripheral cardio-respiratory effects of saxitoxin (STX) in urethane-anesthetized guinea-pigs. Toxicon. https://doi.org/10.1016/0041-0101(93)90119-4
Chen L, Xie P (2016) Mechanisms of microcystin-induced cytotoxicity and apoptosis. Mini Rev Med Chem 16:1018–1031. https://doi.org/10.2174/1389557516666160219130407
CAS Article PubMed Google Scholar
Chen L, Zhang X, Zhou W, Qiao Q, Liang H, Li G, Wang J, Cai F (2013) The interactive effects of cytoskeleton disruption and mitochondria dysfunction lead to reproductive toxicity induced by microcystin-LR. PLoS ONE 8:e53949. https://doi.org/10.1371/journal.pone.0053949
CAS Article PubMed PubMed Central Google Scholar
Chen L, Chen J, Zhang X, Xie P (2016a) A review of reproductive toxicity of microcystins. J Hazard Mater 301:381–399. https://doi.org/10.1016/j.jhazmat.2015.08.041
CAS Article PubMed Google Scholar
Chen L, Li S, Guo X, Xie P, Chen J (2016b) The role of GSH in microcystin-induced apoptosis in rat liver: Involvement of oxidative stress and NF-κB. Environ Toxicol 31:552–560. https://doi.org/10.1002/tox.22068
CAS Article PubMed Google Scholar
Chen L, Hu Y, He J, Chen J, Giesy JP, Xie P (2017) Responses of the proteome and metabolome in livers of zebrafish exposed chronically to environmentally relevant concentrations of microcystin-LR. Environ Sci Technol 51:596–607. https://doi.org/10.1021/acs.est.6b03990
CAS Article PubMed Google Scholar
Chen L, Giesy JP, Xie P (2018a) The dose makes the poison. Sci Total Environ 621:649–653. https://doi.org/10.1016/j.scitotenv.2017.11.218
CAS Article PubMed Google Scholar
Chen L, Wang Y, Giesy JP, Chen F, Shi T, Chen J, Xie P (2018b) Microcystin-LR affects the hypothalamic-pituitary-inter-renal (HPI) axis in early life stages (embryos and larvae) of zebrafish. Environ Pollut 241:540–548. https://doi.org/10.1016/j.envpol.2018.05.024
留言 (0)