Russo, M., & Russo, G. L. M. (2018). Autophagy inducers in cancer. Biochem Pharmaco, 1(153), 51–61.
Martina, J. A., Chen, Y., Gucek, M., & Puertollano, R. (2012). MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB. Autophagy, 8, 903–914. https://doi.org/10.4161/auto.19653.
CAS PubMed PubMed Central Article Google Scholar
Sridharan S, Jain K. Basu A, Regulation of autophagy by kinases. Cancers 3, 2630–2654. https://doi.org/10.3390/cancers3022630
Aizawa, S., Hoki, M., & Yamamuro, Y. (2017). Lactoferrin promotes autophagy via AMP-activated protein kinase activation through low-density lipoprotein receptor-related protein 1. Biochem Biophys Res Commun, 493(1), 509–513.
CAS PubMed Article Google Scholar
Mukhopadhyay, S., Sinha, N., Das, D. N., Panda, P. K., Naik, P. P., & Bhutia, S. K. (2016). Clinical relevance of autophagic therapy in cancer: Investigating the current trends, challenges, and future prospects. Crit Rev Clin Lab Sci. 53(4), 228–252.
Galluzzi, L., Buqué, A., Kepp, O., Zitvogel, L., & Kroemer, G. (2017). Immunogenic cell death in cancer and infectious disease. Nat Rev Immunol., 17.2, 97–111.
Santana-Codina N, Mancias J, Kimmelman AC, The role of autophagy in cancer. Annu Rev Cancer Biol. 1, 19–39.
Galluzzi, L., Pietrocola, F., Bravo‐San Pedro, J. M., Amaravadi, R. K., Baehrecke, E. H., Cecconi, F., & Kroemer, G. (2015). Autophagy in malignant transformation and cancer progression. The EMBO J., 34.7, 856–880.
Wilde, L., Tanson, K., Curry, J., & Martinez-Outschoorn, U. (2018). Autophagy in cancer: a complex relationship. Biochem J., 475.11, 1939–1954.
Wu, C. P., & Ambudkar, S. V. (2014). The pharmacological impact of ATP-binding cassette drug transporters on vemurafenib-based therapy. Acta Pharm Sin B., 4.2, 105–111.
Ouyang, L., Shi, Z., Zhao, S., Wang, F. T., Zhou, T. T., Liu, B., & Bao, J. K. (2012). Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. Cell Prolif., 45. 6, 487–498.
Zhao, Y. G., Codogno, P., & Zhang, H. (2021). Machinery regulation and pathophysiological implications of autophagosome maturation. Nat Rev Mol Cell Biol, 22, 733–750.
CAS PubMed PubMed Central Article Google Scholar
Hara, T., Takamura, A., Kishi, C., Iemura, S. I., Natsume, T., Guan, J. L., & Mizushima, N. (2008). FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol., 181.3, 497–510.
Randhawa, R., Sehgal, M., Singh, T. R., Duseja, A., & Changotra, H. (2015). Unc-51 like kinase 1 (ULK1) in silico analysis for biomarker identification: a vital component of autophagy. Gene, 562.1, 40–49.
Li, F., Chung, T., & Vierstra, R. D. (2014). AUTOPHAGY-RELATED11 plays a critical role in general autophagy-and senescence-induced mitophagy in Arabidopsi. The Plant Cell, 26.2, 788–807.
Hara, T., & Mizushima, N. (2009). Role of ULK-FIP200 complex in mammalian autophagy: FIP200, a counterpart of yeast Atg17. Autophagy, 5.1, 85–87.
Hosokawa, N., Hara, T., Kaizuka, T., Kishi, C., Takamura, A., Miura, Y., & Mizushima, N. (2009). Nutrient-dependent mTORC1 association with the ULK1–Atg13–FIP200 complex required for autophagy. Mol Biol Cell., 20.7, 1981–1991.
Ganley, I. G., Lam, D. H., Wang, J., Ding, X., Chen, S., & Jiang, X. (2009). ULK1· ATG13· FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biolo Chem, 284.18, 12297–12305.
Mercer, C. A., Kaliappan, A., & Dennis, P. B. (2009). A novel human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy. Autophagy, 5.5, 649–662.
Dong, Z., Wang, Y., Liu, W. Z., Shu, Q. S., Cai, J., & Tang, Y. C. (2020). AMPK/mTOR signaling in autophagy regulation during cisplatin-induced acute kidney injury. Front Physiol, 11, 1679.
González-Chávez, S. A., Arévalo-Gallegos, S., & Rascón-Cruz, Q. (2009). Lactoferrin: structure, function and applications. Int J Antimicrob Agents, 33.4, 301–e1.
Stevens, R. G., Jones, D. Y., Micozzi, M. S., & Taylor, P. R. (1988). Body iron stores and the risk of cancer. N Engl J Med., 319.16, 1047–1052.
Grosso, R. A., Caldarone, P. V. S., Sánchez, M. C., Chiabrando, G. A., Colombo, M. I., & Fader, C. M. (2019). Hemin induces autophagy in a leukemic erythroblast cell line through the LRP1 receptor. Biosci Rep., 39, 1.
Sui, X., Chen, R., Wang, Z., Huang, Z., Kong, N., Zhang, M., & Pan, H. (2013). Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment. Cell Death Dis., 10, e838.
Benkert, P., Biasini, M., & Schwede, T. (2011). Toward the estimation of the absolute quality of individual protein structure models. Bioinformatics, 27, 343–350.
CAS PubMed Article Google Scholar
Wiederstein, M., & Sippl, M. J. (2007). ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins. Nucleic Acids Res., 35, W407–W410.
PubMed PubMed Central Article Google Scholar
Anderson, R. J., Weng, Z., Campbell, R. K., & Jiang, X. (2005). Main-chain conformational tendencies of amino acids. Proteins, 60.4, 679–89.
Desta, I. T., Porter, K. A., Xia, B., Kozakov, D., & Vajda, S. (2020). Performance and its limits in rigid body protein-protein docking. Structure, 28. 9, 1071–1081.
Kozakov, D., Hall, D. R., Xia, B., Porter, K. A., Padhorny, D., Yueh, C., Beglov, D., & Vajda, S. (2017). The ClusPro web server for protein-protein docking. Nature Protocols, 12.2, 255–278.
Zhou, S., Zhao, L., Kuang, M., Zhang, B., Liang, Z., Yi, T., & Zhao, X. (2012). Autophagy in tumorigenesis and cancer therapy: Dr. Jekyll or Mr. Hyde. Cancer Lett., 323.2, 115–127.
Zhang, Y., Nicolau, A., Lima, C. F., & Rodrigues, L. R. (2014). Bovine lactoferrin induces cell cycle arrest and inhibits mTOR signaling in breast cancer cells. Nutr Cancer, 66.8, 1371–1385.
Bononi, A., Agnoletto, C., De Marchi, E., Marchi, S., Patergnani, S., Bonora, M., & Pinton, P. (2011). Protein kinases and phosphatases in the control of cell fate. Enzyme Res., 2011, 329098 https://doi.org/10.4061/2011/329098.
CAS PubMed PubMed Central Article Google Scholar
Mizushima, N. (2010). The role of the Atg1/ULK1 complex in autophagy regulation. Curr Opin Cell Biol., 22. 2, 132–139.
Tang, J., Deng, R., Luo, R. Z., Shen, G. P., Cai, M. Y., Du, Z. M., & Zhu, X. F. (2012). Low expression of ULK1 is associated with operable breast cancer progression and is an adverse prognostic marker of survival for patients. Breast Cancer Res Treat., 134. 2, 549–560.
Khan, S. H., & Kumar, R. (2012). Role of an intrinsically disordered conformation in AMPK-mediated phosphorylation of ULK1 and regulation of autophagy. Mol Biosyst., 8.1, 91–96.
Xue Y, Wang D, Peng D. (2021) Bioinformatics Technologies in Autophagy Research In. Autophagy: Biology and Diseases, Springer, Singapore, 387–453.
Lee, J. W., Park, S., Takahashi, Y., & Wang, H. G. (2010). The association of AMPK with ULK1 regulates autophagy. PloS one, 5.11, e15394.
Dwivedi, P., & Greis, K. D. (2017). Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies. Exp Hematol, 46, 9–20.
CAS PubMed Article Google Scholar
Dwivedi, P. (2021). ROS mediated apoptotic pathways in primary effusion lymphoma: comment on induction of apoptosis by Shikonin through ROS-mediated intrinsic and extrinsic pathways in primary effusion lymphoma. Transl Oncol., 14, 101061.
PubMed PubMed Central Article Google Scholar
Xiao, Y., Monitto, C. L., Minhas, K. M., & Sidransky, D. (2004). Lactoferrin down-regulates G1 cyclin dependent kinases during growth arrest of head and neck cancer cells. Clin Cancer Res., 10, 8683–8686.
CAS PubMed Article Google Scholar
Hsu, Y. H., Chiu, I. J., Lin, Y. F., Chen, Y. J., Lee, Y. H., & Chiu, H. W. (2020). Lactoferrin contributes a renoprotective effect in acute kidney injury and early renal fibrosis. Pharmaceutics, 12.5, 434.
Dwivedi, P., Rodriguez, J., Ibe, N. U., & Weers, P. M. M. (2016). Deletion of the N- or C-terminal helix of apolipophorin III to create a four-helix bundle protein. Biochem, 5.55(26), 3607–3615.
Behrends, C., Sowa, M. E., Gygi, S. P., & Harper, J. (2010). Network organization of the human autophagy system. Nature, 466.7302, 68–76.
Denton, D., Nicolson, S., & Kumar, S. (2012). Cell death by autophagy: facts and apparent artefacts. Cell Death Differ, 19.1, 87–95.
留言 (0)