Crosby D, Bhatia S, Brindle KM, Coussens LM, Dive C, Emberton M, Esener S, Fitzgerald RC, Gambhir SS, Kuhn P et al (2022) Early detection of cancer. Science 375:eaay9040. https://doi.org/10.1126/science.aay9040
Wang M, Yu F, Zhang Y, Chang W, Zhou M (2022) The effects and mechanisms of flavonoids on cancer prevention and therapy: focus on gut microbiota. Int J Biol Sci 18:1451–1475. https://doi.org/10.7150/ijbs.68170
CAS Article PubMed PubMed Central Google Scholar
Wang M, Chen X, Yu F, Ding H, Zhang Y, Wang K (2021) Extrachromosomal circular DNAs: origin, formation and emerging function in cancer. Int J Biol Sci 17:1010–1025. https://doi.org/10.7150/ijbs.54614
Article PubMed PubMed Central Google Scholar
Shan P, Yang F, Qi H, Hu Y, Zhu S, Sun Z, Zhang Z, Wang C, Hou C, Yu J et al (2021) Alteration of MDM2 by the small molecule YF438 exerts antitumor effects in triple-negative breast cancer. Cancer Res 81:4027–4040. https://doi.org/10.1158/0008-5472.CAN-20-0922
CAS Article PubMed Google Scholar
Schumacher TN, Thommen DS (2022) Tertiary lymphoid structures in cancer. Science 375: eabf9419. https://doi.org/10.1126/science.abf9419
Liu Y, Ao X, Zhou X, Du C, Kuang S (2022) The regulation of PBXs and their emerging role in cancer. J Cell Mol Med 26:1363–1379. https://doi.org/10.1111/jcmm.17196
Article PubMed PubMed Central Google Scholar
Jonckheere S, Adams J, De Groote D, Campbell K, Berx G, Goossens S (2022) Epithelial-mesenchymal transition (EMT) as a therapeutic target. Cells Tissues Organs 211:157–182. https://doi.org/10.1159/000512218
CAS Article PubMed Google Scholar
Zhang YF, Shan C, Wang Y, Qian LL, Jia DD, Zhang YF, Hao XD, Xu HM (2020) Cardiovascular toxicity and mechanism of bisphenol A and emerging risk of bisphenol S. The Science of the total environment 723:137952. https://doi.org/10.1016/j.scitotenv.2020.137952
CAS Article PubMed Google Scholar
Gottgens EL, Span PN, Zegers MM (2016) Roles and regulation of epithelial splicing regulatory proteins 1 and 2 in epithelial-mesenchymal transition. Int Rev Cell Mol Biol 327:163–194. https://doi.org/10.1016/bs.ircmb.2016.06.003
CAS Article PubMed Google Scholar
Lyu J, Cheng C (2022) Regulation of alternative splicing during epithelial-mesenchymal transition. Cells Tissues Organs 211:238–251. https://doi.org/10.1159/000518249
CAS Article PubMed Google Scholar
Liu X, Wang Q, Song S, Feng M, Wang X, Li L, Liu Y, Shi C (2021) Epithelial splicing regulatory protein 1 is overexpressed in breast cancer and predicts poor prognosis for breast cancer patients. Medical science monitor : international medical journal of experimental and clinical research 27:e931102. https://doi.org/10.12659/MSM.931102
Carroll SH, Macias Trevino C, Li EB, Kawasaki K, Myers N, Hallett SA, Alhazmi N, Cotney J, Carstens RP, Liao EC (2020) An Irf6-Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates. Development. https://doi.org/10.1242/dev.194498
Article PubMed PubMed Central Google Scholar
Sagnol S, Marchal S, Yang Y, Allemand F, de Santa BP (2016) Epithelial splicing regulatory protein 1 (ESRP1) is a new regulator of stomach smooth muscle development and plasticity. Dev Biol 414:207–218. https://doi.org/10.1016/j.ydbio.2016.04.015
CAS Article PubMed Google Scholar
Deng G, Zhou X, Chen L, Yao Y, Li J, Zhang Y, Luo C, Sun L, Tang J (2020) High expression of ESRP1 regulated by circ-0005585 promotes cell colonization in ovarian cancer. Cancer Cell Int 20:174. https://doi.org/10.1186/s12935-020-01254-3
CAS Article PubMed PubMed Central Google Scholar
Hyun J, Al Abo M, Dutta RK, Oh SH, Xiang K, Zhou X, Maeso-Diaz R, Caffrey R, Sanyal AJ, Freedman JA et al (2021) Dysregulation of the ESRP2-NF2-YAP/TAZ axis promotes hepatobiliary carcinogenesis in non-alcoholic fatty liver disease. J Hepatol 75:623–633. https://doi.org/10.1016/j.jhep.2021.04.033
CAS Article PubMed PubMed Central Google Scholar
Faux MC, King LE, Kane SR, Love C, Sieber OM, Burgess AW (2021) APC regulation of ESRP1 and p120-catenin isoforms in colorectal cancer cells. Mol Biol Cell 32:120–130. https://doi.org/10.1091/mbc.E20-05-0321
CAS Article PubMed PubMed Central Google Scholar
Gokmen-Polar Y, Neelamraju Y, Goswami CP, Gu Y, Gu X, Nallamothu G, Vieth E, Janga SC, Ryan M, Badve SS (2019) Splicing factor ESRP1 controls ER-positive breast cancer by altering metabolic pathways. EMBO Rep. https://doi.org/10.15252/embr.201846078
Article PubMed PubMed Central Google Scholar
Munkley J, Li L, Krishnan SRG, Hysenaj G, Scott E, Dalgliesh C, Oo HZ, Maia TM, Cheung K, Ehrmann I et al (2019) Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer. Elife. https://doi.org/10.7554/eLife.47678
Article PubMed PubMed Central Google Scholar
Hayakawa A, Saitoh M, Miyazawa K (2017) Dual roles for epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) in cancer progression. Adv Exp Med Biol 925:33–40. https://doi.org/10.1007/5584_2016_50
CAS Article PubMed Google Scholar
Schmidt C, Urlaub H (2017) Combining cryo-electron microscopy (cryo-EM) and cross-linking mass spectrometry (CX-MS) for structural elucidation of large protein assemblies. Curr Opin Struct Biol 46:157–168. https://doi.org/10.1016/j.sbi.2017.10.005
CAS Article PubMed Google Scholar
Earl LA, Falconieri V, Milne JL, Subramaniam S (2017) Cryo-EM: beyond the microscope. Curr Opin Struct Biol 46:71–78. https://doi.org/10.1016/j.sbi.2017.06.002
CAS Article PubMed PubMed Central Google Scholar
Weisse J, Rosemann J, Krauspe V, Kappler M, Eckert AW, Haemmerle M, Gutschner T (2020) RNA-binding proteins as regulators of migration, invasion and metastasis in oral squamous cell carcinoma. Int J Mol Sci. https://doi.org/10.3390/ijms21186835
Article PubMed PubMed Central Google Scholar
Lee S, Sears MJ, Zhang Z, Li H, Salhab I, Krebs P, Xing Y, Nah HD, Williams T, Carstens RP (2020) Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. Development. https://doi.org/10.1242/dev.187369
Article PubMed PubMed Central Google Scholar
Wineberg Y, Bar-Lev TH, Futorian A, Ben-Haim N, Armon L, Ickowicz D, Oriel S, Bucris E, Yehuda Y, Pode-Shakked N et al (2020) Single-cell RNA sequencing reveals mRNA splice isoform switching during kidney development. J Am Soc Nephrol 31:2278–2291. https://doi.org/10.1681/ASN.2019080770
CAS Article PubMed PubMed Central Google Scholar
Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K et al (2017) ESRP1 mutations cause hearing loss due to defects in alternative splicing that disrupt cochlear development. Dev Cell 43(318–331):e315. https://doi.org/10.1016/j.devcel.2017.09.026
Bebee TW, Sims-Lucas S, Park JW, Bushnell D, Cieply B, Xing Y, Bates CM, Carstens RP (2016) Ablation of the epithelial-specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number. Dev Dyn 245:991–1000. https://doi.org/10.1002/dvdy.24431
CAS Article PubMed PubMed Central Google Scholar
Saeidi S, Shapouri F, de Iongh RU, Casagranda F, Sutherland JM, Western PS, McLaughlin EA, Familari M, Hime GR (2018) Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis. PLoS ONE 13:e0190925. https://doi.org/10.1371/journal.pone.0190925
CAS Article PubMed PubMed Central Google Scholar
Jia J, Shi E, Zhou X, Zhu S, Li J, Zhang J, Yu J, Wang S, Feng L (2020) Expression of ESRP1 at human fetomaternal interface and involvement in trophoblast migration and invasion. Placenta 90:18–26. https://doi.org/10.1016/j.placenta.2019.11.005
CAS Article PubMed Google Scholar
Yu L, Zhang H, Guan X, Qin D, Zhou J, Wu X (2021) Loss of ESRP1 blocks mouse oocyte development and leads to female infertility. Development. https://doi.org/10.1242/dev.196931
Article PubMed PubMed Central Google Scholar
Weng CM, Li Q, Chen KJ, Xu CX, Deng MS, Li T, Zhang DD, Duan ZX, Chen ZQ, Li GH et al (2020) Bleomycin induces epithelial-to-mesenchymal transition via bFGF/PI3K/ESRP1 signaling in pulmonary fibrosis. Biosci Rep. https://doi.org/10.1042/BSR20190756
Hyun J, Sun Z, Ahmadi AR, Bangru S, Chembazhi UV, Du K, Chen T, Tsukamoto H, Rusyn I, Kalsotra A et al (2020) Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis. J Clin Invest 130:2129–2145. https://doi.org/10.1172/JCI132691
CAS Article PubMed PubMed Central Google Scholar
Zuo YB, Zhang YF, Zhang R, Tian JW, Lv XB, Li R, Li SP, Cheng MD, Shan J, Zhao Z et al (2022) Ferroptosis in cancer progression: role of noncoding RNAs. Int J Biol Sci 18:1829–1843. https://doi.org/10.7150/ijbs.66917
CAS Article PubMed PubMed Central Google Scholar
Baeissa HM, Benstead-Hume G, Richardson CJ, Pearl FM (2016) Mutational patterns in oncogenes and tumour suppressors. Biochem Soc Trans 44:925–931. https://doi.org/10.1042/BST20160001
CAS Article PubMed Google Scholar
Ivanov I, Lo KC, Hawthorn L, Cowell JK, Ionov Y (2007) Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells. Oncogene 26:2873–2884. https://doi.org/10.1038/sj.onc.1210098
CAS Article PubMed Google Scholar
Li S, Yang S, Shi J, Ding Y, Gao W, Cheng M, Sun Y, Xie Y, Sang M, Yang H et al (2021) Recognition of the organ-specific mutations in metastatic breast cancer by circulating tumor cells isolated in vivo. Neoplasma 68:31–39. https://doi.org/10.4149/neo_2020_200317N275
CAS Article PubMed Google Scholar
Horvath A, Pakala SB, Mudvari P, Reddy SD, Ohshiro K, Casimiro S, Pires R, Fuqua SA, Toi M, Costa L et al
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