Lin CY, Xu LH, You L. Technical approaches for studying the communications between osteocytes and cancer cells. Bone cancer: bone sarcomas and bone metastases - from Bench to Bedside 2021:157–168. https://doi.org/10.1016/B978-0-12-821666-8.00067-0.
Uda Y, Azab E, Sun N, Shi C, Pajevic PD. Osteocyte mechanobiology. Curr Osteoporos Rep. 2017;15:318–25. https://doi.org/10.1007/s11914-017-0373-0.
Article PubMed PubMed Central Google Scholar
You L, Cowin SC, Schaffler MB, Weinbaum S. A model for strain amplification in the actin cytoskeleton of osteocytes due to fluid drag on pericellular matrix. J Biomech. 2001;34:1375–86. https://doi.org/10.1016/S0021-9290(01)00107-5.
CAS Article PubMed Google Scholar
Han Y, Cowin SC, Schaffler MB, Weinbaum S. Mechanotransduction and strain amplification in osteocyte cell processes. Proc Natl Acad Sci USA. 2004;101:16689–94. https://doi.org/10.1073/pnas.0407429101.
CAS Article PubMed PubMed Central Google Scholar
Wang Y, McNamara LM, Schaffler MB, Weinbaum S. A model for the role of integrins in flow induced mechanotransduction in osteocytes. Proc Natl Acad Sci USA. 2007;104:15941–6. https://doi.org/10.1073/pnas.0707246104.
Article PubMed PubMed Central Google Scholar
Wang Y, McNamara LM, Schaffler MB, Weinbaum S. Strain amplification and integrin based signaling in osteocytes. J Musculoskelet Neuronal Interact. 2008;8:332–4.
Pathak JL, Bravenboer N, Luyten FP, Verschueren P, Lems WF, Klein-Nulend J, et al. Mechanical loading reduces inflammation-induced human osteocyte-to-osteoclast communication. Calcif Tissue Int. 2015;97:169–78. https://doi.org/10.1007/S00223-015-9999-z.
CAS Article PubMed PubMed Central Google Scholar
Kulkarni RN, Bakker AD, Everts V, Klein-Nulend J. Mechanical loading prevents the stimulating effect of IL-1β on osteocyte-modulated osteoclastogenesis. Biochem Biophys Res Commun. 2012;420:11–6. https://doi.org/10.1016/j.bbrc.2012.02.099.
CAS Article PubMed Google Scholar
Fan Y, Jalali A, Chen A, Zhao X, Liu S, Teli M, et al. Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion. Bone Res. 2020;8:1–11. https://doi.org/10.1038/s41413-020-0083-6.
Eichholz KF, Woods I, Riffault M, Johnson GP, Corrigan M, Lowry MC, et al. Human bone marrow stem/stromal cell osteogenesis is regulated via mechanically activated osteocyte-derived extracellular vesicles. Stem Cells Transl Med. 2020;9:1431–47. https://doi.org/10.1002/sctm.19-0405.
CAS Article PubMed PubMed Central Google Scholar
Cheung WY, Liu C, Tonelli-Zasarsky RML, Simmons CA, You L. Osteocyte apoptosis is mechanically regulated and induces angiogenesis in vitro. J Orthop Res. 2011;29:523–30. https://doi.org/10.1002/jor.21283.
Asada N, Katayama Y, Sato M, Minagawa K, Wakahashi K, Kawano H, et al. Matrix-embedded osteocytes regulate mobilization of hematopoietic stem/progenitor cells. Cell Stem Cell. 2013;12:737–47. https://doi.org/10.1016/j.stem.2013.05.001.
CAS Article PubMed Google Scholar
Croucher PI, McDonald MM, Martin TJ. Bone metastasis: the importance of the neighbourhood. Nat Rev Cancer. 2016;16:373–86. https://doi.org/10.1038/nrc.2016.44.
CAS Article PubMed Google Scholar
Méndez-Ferrer S, Bonnet D, Steensma DP, Hasserjian RP, Ghobrial IM, Gribben JG, et al. Bone marrow niches in haematological malignancies. Nat Rev Cancer. 2020;20:285–98. https://doi.org/10.1038/s41568-020-0245-2.
CAS Article PubMed Google Scholar
Macedo F, Ladeira K, Pinho F, Saraiva N, Bonito N, Pinto L, et al. Bone metastases: an overview. Oncol Rev. 2017;11:321. https://doi.org/10.4081/oncol.2017.321.
CAS Article PubMed PubMed Central Google Scholar
Coughlin TR, Romero-Moreno R, Mason DE, Nystrom L, Boerckel JD, Niebur G, et al. Bone: a fertile soil for cancer metastasis. Curr Drug Targets. 2017;18:1281–95. https://doi.org/10.2174/1389450117666161226121650.
CAS Article PubMed PubMed Central Google Scholar
Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer. 2002;2:584–93. https://doi.org/10.1038/nrc867.
CAS Article PubMed Google Scholar
Zhou JZ, Riquelme MA, Gao X, Ellies LG, Sun LZ, Jiang JX. Differential impact of adenosine nucleotides released by osteocytes on breast cancer growth and bone metastasis. Oncogene. 2014;34:1831–42. https://doi.org/10.1038/onc.2014.113.
CAS Article PubMed PubMed Central Google Scholar
Sottnik JL, Dai J, Zhang H, Campbell B, Keller ET. Tumor-induced pressure in the bone microenvironment causes osteocytes to promote the growth of prostate cancer bone metastases. Cancer Res. 2015;75:2151–8. https://doi.org/10.1158/0008-5472.can-14-2493.
CAS Article PubMed PubMed Central Google Scholar
Delgado-Calle J, Anderson J, Cregor MD, Hiasa M, Chirgwin JM, Carlesso N, et al. Bidirectional notch signaling and osteocyte-derived factors in the bone marrow microenvironment promote tumor cell proliferation and bone destruction in multiple myeloma. Cancer Res. 2016;76:1089–100. https://doi.org/10.1158/0008-5472.can-15-1703.
CAS Article PubMed PubMed Central Google Scholar
Wang S, Pei S, Wasi M, Parajuli A, Yee A, You L, et al. Moderate tibial loading and treadmill running, but not overloading, protect adult murine bone from destruction by metastasized breast cancer. Bone. 2021;153:116100. https://doi.org/10.1016/j.bone.2021.116100.
CAS Article PubMed Google Scholar
Melville KM, Robling AG, van der Meulen MC. In vivo axial loading of the mouse tibia. Methods Mol Biol. 2015;1226:99–115. https://doi.org/10.1007/978-1-4939-1619-1.
Article PubMed PubMed Central Google Scholar
Gardinier JD, Rostami N, Juliano L, Zhang C. Bone adaptation in response to treadmill exercise in young and adult mice. Bone Rep. 2018;8:29–37. https://doi.org/10.1016/j.bonr.2018.01.003.
Article PubMed PubMed Central Google Scholar
Vanleene M, Shefelbine SJ. Therapeutic impact of low amplitude high frequency whole body vibrations on the osteogenesis imperfecta mouse bone. Bone. 2013;53:507–14. https://doi.org/10.1016/j.bone.2013.01.023.
Article PubMed PubMed Central Google Scholar
Lynch MA, Brodt MD, Silva MJ. Skeletal effects of whole-body vibration in adult and aged mice. J Orthop Res. 2010;28:241–7. https://doi.org/10.1002/jor.20965.
Article PubMed PubMed Central Google Scholar
Nijweide PJ, Mulder RJP. Identification of osteocytes in osteoblast-like cell cultures using a monoclonal antibody specifically directed against osteocytes. Histochemistry. 1986;84:342–7. https://doi.org/10.1007/BF00482961.
CAS Article PubMed Google Scholar
Bruder SP, Caplan AI. Terminal differentiation of osteogenic cells in the embryonic chick tibia is revealed by a monoclonal antibody against osteocytes. Bone. 1990;11:189–98. https://doi.org/10.1016/8756-3282(90)90213-i.
CAS Article PubMed Google Scholar
Kalajzic I, Matthews BG, Torreggiani E, Harris MA, Divieti Pajevic P, Harris SE. In vitro and in vivo approaches to study osteocyte biology. Bone. 2013;54:296–306. https://doi.org/10.1016/j.bone.2012.09.040.
CAS Article PubMed Google Scholar
Frangos JA, McIntire LV, Eskin SG. Shear stress induced stimulation of mammalian cell metabolism. Biotechnol Bioeng. 1988;32:1053–60. https://doi.org/10.1002/bit.260320812.
CAS Article PubMed Google Scholar
Huesa C, Helfrich MH, Aspden RM. Parallel-plate fluid flow systems for bone cell stimulation. J Biomech. 2010;43:1182–9. https://doi.org/10.1016/j.jbiomech.2009.11.029.
Middleton K, Al-Dujaili S, Mei X, Günther A, You L. Microfluidic co-culture platform for investigating osteocyte-osteoclast signalling during fluid shear stress mechanostimulation. J Biomech. 2017;59:35–42. https://doi.org/10.1016/j.jbiomech.2017.05.012.
CAS Article PubMed Google Scholar
•• Xu L, Song X, Carroll G, You L. Novel in vitro microfluidic platform for osteocyte mechanotransduction studies. Integr Biol (Camb) 2020:12:303–310. https://doi.org/10.1093/intbio/zyaa025. Microfluidic platform for investigating mechanically stimulated osteocytes in the regulation of osteoclastogenesis under multi-level shear stress.
•• Mei X, Middleton K, Shim D, Wan Q, Xu L, Ma YHV, et al. Microfluidic platform for studying osteocyte mechanoregulation of breast cancer bone metastasis. Integr Biol (Camb) 2019:11:119–129. https://doi.org/10.1093/intbio/zyz008. Microfludic co-culture platform to study osteocyte regulation of breast cancer extravasation under fluid flow.
• Song X, Lin CY, Arjun R, Ke Y, Wang L, You L. Vibration in preventing breast cancer bone metastasis. JBMR 2022:37:202. Microfludic co-culture platform to study osteocyte regulation of breast cancer extravasation under vibration.
George EL, Truesdell SL, York SL, Saunders MM. Lab-on-a-chip platforms for quantification of multicellular interactions in bone remodeling. Exp Cell Res. 2018;365:106–18. https://doi.org/10.1016/j.yexcr.2018.02.027.
CAS Article PubMed Google Scholar
Wei C, Fan B, Chen D, Liu C, Wei Y, Huo B, et al. Osteocyte culture in microfluidic devices. Biomicrofluidics. 2015;9:1–10. https://doi.org/10.1063/1.4905692.
Ono T, Nakashima T. Recent advances in osteoclast biology. Histochem Cell Biol. 2018;149:325–41. https://doi.org/10.1007/s00418-018-1636-2.
CAS Article PubMed Google Scholar
Zhao S, Kato Y, Zhang Y, Harris S, Ahuja SS, Bonewald LF. MLO-Y4 osteocyte-like cells support osteoclast formation and activation. J Bone Miner Res. 2002;17:2068–79. https://doi.org/10.1359/jbmr.2002.17.11.2068.
留言 (0)