Available online 21 September 2022

A 51-year-old man, only treated with levodopa, underwent subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson's disease. Immediate postoperative computed tomography (CT) was normal (Fig. 1A). Stimulation led to major clinical improvement allowing a dramatic reduction of antiparkinsonian treatment (1400 mg levodopa daily dose before surgery vs. 100 mg after surgery). He returned home 10 days after surgery. One week later, he presented very severe apathy with mutism, indifference

Stephane Thobois and Teodor Danaila received honorarium from Boston and Medtronic.

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