Eucarbwenstols A–H, eight novel compounds from Eucalyptus robusta prevents MPC-5 injury via ROS modulation and regulation of mitochondrial membrane potential

Keywords

Eucalyptus robusta

Formyl phloroglucinol meroterpenoids

MPC-5

ROS

Mitochondrial membrane potential

AbbreviationsDEPT

Distortionless Enhancement by Polarization Transfer

ECD

Electron Circular Dichroism

FPMs

Formyl phloroglucinol meroterpenoids

HMBC

1H detected Heteronuclear Multiple Bond Correlation

HRESIMS

High Resolution Electrospray Ionization Mass Spectroscopy

HSQC

Heteronuclear Singular Quantum Correlation

IC50

half-maximal Inhibitory Concentration

IHD

Indices of Hydrogen Deficiency

MMP

Mitochondrial Membrane Potential

MTT

3-(4,5-dimethyl thiazol-2-yl)-2,5 diphenyl tetrazolium bromide

NMR

Nuclear Magnetic Resonance

PBS

Phosphate Buffered Saline

PHPLC

Preparative High Performance Liquid Chromatography

QTof

Quadrupole Time of Flight

ROS

Reactive Oxygen Species

RP-MPLC

Reverse Phase Medium Pressure Liquid Chromatography

SLE

Systemic Lupus Erythematosus

TGF-β

Transforming Growing Factor-β

UV

Ultraviolet and Visible spectrum

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