Available online 21 September 2022, 115819
Highlights•High levels of beta-lactamase-producers in hospital WW with and without treatment.
•The most frequent beta-lactamase-producing GNB were C. freundii and E. coli
•The beta-lactamase-producing GNB showed a high diversity of MDR profiles.
•Hospital WW could influence the dissemination of antimicrobial resistance.
•Importance of regulating hospital wastewater in developing countries.
AbstractHospital wastewater (HWW) discharges are among the main sources of antibiotic-resistant bacteria. This study detected a high frequency of beta-lactamase-producing Gram-negative Bacilli in HWW of different geographical regions of Colombia, even in the presence of the wastewater treatment plant, highlighting the importance of regulating these environments in developing countries.
KeywordsAntimicrobial resistance
hospital wastewater
multidrug-resistant
beta-lactamases
carbapenemases
© 2022 The Author(s). Published by Elsevier Inc.
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