Available online 23 September 2022, 115820
Highlights•Ceftaroline was tested against 9,268 Staphylococcus aureus from 33 US hospitals
•Susceptibility results were stratified by infection type and resistance profile
•Ceftaroline susceptibility ranged from 95.4% (pneumonia) to 98.5% (SSSI)
•Ceftaroline retained potent and broad-spectrum activity against MRSA (93.4%S)
•Highest ceftaroline MIC value was 2 mg/L
AbstractCeftaroline and comparators were tested against 9,268 Staphylococcus aureus isolates from 33 United States hospitals (2018-2020). Ceftaroline (MIC50/90, 0.25/1 mg/L) susceptibility ranged from 95.4% (pneumonia) to 98.5% (skin and skin structure) and was 97.2% overall. Ceftaroline retained potent and broad-spectrum activity against methicillin-resistant isolates, with a 93.4% overall susceptibility.
KeywordsMRSA
skin and skin structure infection
pneumonia
ceftaroline
Staphylococcus aureus
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