mBC
metastatic breast cancer
TME
tumor microenvironment
HER2
human epidermal growth factor receptor 2
BSE
breast self-examination
MRI
magnetic resonance imaging
TNBC
triple negative breast cancer
PD-L1
programmed death-ligand 1
AC
adriamycin/cyclophosphamide
AC-T
adriamycin/cyclophosphamide/paclitaxel
CMF
cyclophosphamide/methotrexate/5-fluorouracil
TC
docetaxel/cyclophosphamide
NCCN
national comprehensive cancer network
CDK4/6
cyclin-dependent kinase 4 and 6
mTOR
mammalian target of rapamycin
ADC
antibody drug conjugate
PARP
poly (ADP-ribose) polymerase
PTHrP
parathyroid-hormone-related peptide
TIBD
tumor induced bone disease
HSC
hematopoietic stem cell
NK cell
natural killer cell
MDSC
myeloid-derived suppressor cell
TAM
tumor-associated macrophage
Osteomac
osteal macrophage
CAF
cancer associated fibroblast
SRE
skeletal related event
RANKL
receptor activator of the nuclear factor kappa-B ligand
RANK
receptor activator of the nuclear factor kappa-B
CTLA-4
cytotoxic T-lymphocyte-associated protein 4
PD-1
programmed cell death protein 1
LAG-3
lymphocyte activation gene-3
HSPA-4
heat shock protein family A member 4
FLT1
FMS-like tyrosine kinase 1
IDO
indoleamine-pyrrole 2,3-dioxygenase
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