Right ventricular-pulmonary arterial coupling and its relationship to exercise haemodynamics in a continuum of patients with pulmonary vascular disease due to chronic thromboembolism

Abstract

This retrospective study shows that TAPSE/sPAP ratio, a simple surrogate of RV–PA coupling, may help to identify patients with PVD due to chronic thromboembolism and predicts impaired pulmonary exercise haemodynamics https://bit.ly/3osXxzV

Acknowledgements

Claire Mulligan (Beacon Medical Communications Ltd, Brighton, UK) provided editorial support, funded by the University of Giessen.

Footnotes

Author contributions: P. Douschan, K. Tello and M. Richter conceived the project, performed data abstraction and analysis. S. Guth conceived the project and was responsible for final manuscript approval. A.J. Rieth, C.B. Wiedenroth, T. Sassmann and G. Kovacs performed data abstraction. H.A. Ghofrani and W. Seeger were responsible for final manuscript approval. All authors contributed to the writing and editing of the manuscript.

Conflict of interest: C.B. Wiedenroth has received speaker fees and/or consultancy honoraria from Actelion, AOP Orphan Pharmaceuticals AG, Bayer AG, BTG, MSD and Pfizer. S. Guth has received speaker fees and/or consultancy honoraria from Actelion, Bayer, GSK, MSD and Pfizer. A.J. Rieth has received speaker fees from AstraZeneca and Bayer, and congress fees from Johnson & Johnson and Servier. P. Douschan reports lecture honoraria from Actelion and Janssen; and travel support from Actelion, AstraZeneca, Boehringer Ingelheim, GSK, MSD, Novartis and Menarini; outside the submitted work. G. Kovacs reports lecture honoraria and travel support from Actelion, Janssen, Bayer, GSK, MSD, Boehringer Ingelheim, Novartis, Chiesi, Vitalaire, Ferrer and AOP; outside the submitted work. T. Sassmann reports lecture honoraria from Janssen; and travel support from MSD, Vital Air, Boehringer, Actelion and Pfizer; outside the submitted work. W. Seeger reports consulting fees from Abivax, Liquidia, Medspray, Pieris, United Therapeutics and Vectura; outside the submitted work. All other authors have nothing to disclose.

Support statement: P. Douschan was funded by the European Respiratory Society ERS Clinical Training Research Fellowship (CTF202004-00806). K. Tello was funded by the Collaborative Research Center (SFB) 1213 – Pulmonary Hypertension and Cor Pulmonale, grant number SFB1213/1, project B08 (German Research Foundation, Bonn, Germany). M. Richter was funded by the JLU career Project. S. Guth was funded by the Collaborative Research Center (SFB) 1213 – Pulmonary Hypertension and Cor Pulmonale, grant number SFB1213/1, project CP01 (German Research Foundation, Bonn, Germany). Funding information for this article has been deposited with the Crossref Funder Registry.

Received March 11, 2022.Accepted July 22, 2022.Copyright ©The authors 2022. For reproduction rights and permissions contact permissionsersnet.org

留言 (0)

沒有登入
gif