Mathew B, Parambi DG, Mathew GE, Uddin MS, Inasu ST, Kim H, et al. Emerging therapeutic potentials of dual‐acting MAO and AChE inhibitors in Alzheimer’s and Parkinson’s diseases. Arch Pharm. 2019;352:1900177. https://doi.org/10.1002/ardp.201900177.
Li H, Su YS, He W, Zhang JB, Zhang Q, Jing XH, et al. The nonneuronal cholinergic system in the colon: a comprehensive review. FASEB J. 2022;36:e22165. https://doi.org/10.1096/fj.202101529R.
CAS Article PubMed Google Scholar
Taslimi P, Caglayan C, Gulcin İ. The impact of some natural phenolic compounds on carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes: An antidiabetic, anticholinergic, and antiepileptic study. J Biochem Mol Toxicol. 2017;31:e21995. https://doi.org/10.1002/jbt.21995.
Kalamida D, Poulas K, Avramopoulou V, Fostieri E, Lagoumintzis G, Lazaridis K, et al. Muscle and neuronal nicotinic acetylcholine receptors: structure, function and pathogenicity. FEBS J. 2007;274:3799–845. https://doi.org/10.1111/j.1742-4658.2007.05935.x.
CAS Article PubMed Google Scholar
Backos DS, Franklin CC, Reigan P. The role of glutathione in brain tumor drug resistance. Biochem Pharm. 2012;83:1005–12. https://doi.org/10.1016/j.bcp.2011.11.016.
CAS Article PubMed Google Scholar
Jefferies H, Coster J, Khalil A, Bot J, McCauley RD, Hall JC. Glutathione. ANZ J Surg. 2003;73:517–22. https://doi.org/10.1046/j.1445-1433.2003.02682.x.
Türkeş C, Demir Y, Beydemir Ş. Infection medications: assessment in‐vitro glutathione S‐Transferase inhibition and molecular docking study. ChemistrySelect. 2021;6:11915–24. https://doi.org/10.1002/slct.202103197.
Csermely P, Korcsmáros T, Kiss HJ, London G, Nussinov R. Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review. Pharm Ther. 2013;138:333–408. https://doi.org/10.1016/j.pharmthera.2013.01.016.
Anderson AC. The process of structure-based drug design. Chem Biol. 2003;10:787–97. https://doi.org/10.1016/j.chembiol.2003.09.002.
CAS Article PubMed Google Scholar
Cetin A, Bursal E, Türkan F. 2-methylindole analogs as cholinesterases and glutathione S-transferase inhibitors: Synthesis, biological evaluation, molecular docking, and pharmacokinetic studies. Arab J Chem. 2021;14:103449. https://doi.org/10.1016/j.arabjc.2021.103449.
Suzen S. Recent studies and biological aspects of substantial indole derivatives with anti-cancer activity. Curr Org Chem. 2017;21:2068–76.
Singh TP, Singh OM. Recent progress in biological activities of indole and indole alkaloids. Mini Rev Med Chem. 2018;18:9–25.
Abele E, Abele R, Dzenitis O, Lukevics E. Indole and Isatin Oximes: synthesis, reactions, and biological activity. (Review). Chem Hetro Comp. 2003;39:3–35. https://doi.org/10.1023/A:1023008422464.
Suzen S, Cihaner SS, Coban T. Synthesis and comparison of antioxidant properties of Indole‐based melatonin analogue Indole amino acid derivatives. Chem Biol Drug Des. 2012;79:76–83. https://doi.org/10.1111/j.1747-0285.2011.01216.x.
CAS Article PubMed Google Scholar
Mistry B, Keum YS, Kim DH. Synthesis, antioxidant and anticancer screenings of berberine-indole conjugates. Res Chem Intermed. 2016;42:3241–56. https://doi.org/10.1007/s11164-015-2208-x.
Bozorov K, Zhao J, Aisa HA. 1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: a recent overview. Bioorg Med Chem. 2019;27:3511–31. https://doi.org/10.1016/j.bmc.2019.07.005.
CAS Article PubMed PubMed Central Google Scholar
Das A, Greco G, Kumar S, Catanzaro E, Morigi R, Locatelli A, et al. Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1, 2, 3-triazole derivatives. Comput Biol Chem. 2022;97:107641. https://doi.org/10.1016/j.compbiolchem.2022.107641.
CAS Article PubMed Google Scholar
Agalave SG, Maujan SR, Pore VS. Click chemistry: 1, 2, 3‐triazoles as pharmacophores. Asian J Chem. 2011;6:2696–718. https://doi.org/10.1002/asia.201100432.
Narsimha S, Kumar NS, Swamy BK, Reddy NV, Hussain SA, Rao MS. Indole-2-carboxylic acid derived mono and bis 1,4-disubstituted 1,2,3-triazoles: Synthesis, characterization and evaluation of anticancer, antibacterial, and DNA-cleavage activities. Bioorg Med Chem Lett. 2016;26:1639–44. https://doi.org/10.1016/j.bmcl.2016.01.055.
CAS Article PubMed Google Scholar
Jasiewicz B, Kozanecka-Okupnik W, Przygodzki M, Warżajtis B, Rychlewska U, Pospieszny T, et al. Synthesis, antioxidant and cytoprotective activity evaluation of C-3 substituted indole derivatives. Sci Rep. 2021;11:1–14. https://doi.org/10.1038/s41598-021-94904-z.
Goyal D, Kaur A, Goyal B. Benzofuran and indole: promising scaffolds for drug development in Alzheimer’s disease. Chem Med Chem. 2018;13:1275–99. https://doi.org/10.1002/cmdc.201800156.
CAS Article PubMed Google Scholar
Lan TT, Anh DT, Dung DTM, Huong LTT, Park EJ, Jeon HW, et al. Design, synthesis, and bioevaluation of novel oxoindolin-2-one derivatives incorporating 1-benzyl-1H-1,2,3-triazole. Med Chem Res. 2020;29:396–408. https://doi.org/10.1007/s00044-019-02488-1.
Sepehri N, Asemanipoor N, Mousavianfard SA, Hoseini S, Faramarzi MA, Adib M, et al. New acridine-9-carboxamide linked to 1,2,3-triazole-N-phenylacetamide derivatives as potent α-glucosidase inhibitors: design, synthesis, in vitro, and in silico biological evaluations. Med Chem Res. 2020;29:1836–45. https://doi.org/10.1007/s00044-020-02603-7.
Hein JE, Fokin VV. Copper-catalyzed azide–alkynecycloaddition (CuAAC) and beyond: new reactivity of copper(i) acetylides. Chem Soc Rev. 2010;39:1302–15. https://doi.org/10.1039/B904091A.
CAS Article PubMed PubMed Central Google Scholar
Meldal M, Tornøe CW. Cu-Catalyzed Azide-Alkyne Cycloaddition. Chem Rev. 2008;108:2952–3015. https://doi.org/10.1021/cr0783479.
CAS Article PubMed Google Scholar
Rostovtsev VV, Green LG, Fokin VV, Sharpless KB. A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes. Angew Chem Int Ed. 2002;114:2708–11.
Worrell BT, Malik JA, Fokin VV. Direct evidence of a dinuclear copper intermediate in Cu (I)-catalyzed azide-alkyne cycloadditions. Science. 2013;340:457–60. https://doi.org/10.1126/science.1229506.
CAS Article PubMed PubMed Central Google Scholar
Cetin A, Türkan F, Bursal E, Murahari M. Synthesis, characterization, enzyme inhibitory activity, and molecular docking analysis of a new series of Thiophene-based Heterocyclic compounds. Russ J Org Chem. 2021;57:598–604. https://doi.org/10.1134/S107042802104014X.
Aras A, Türkan F, Yildiko U, Atalar MN, Kılıç Ö, Alma MH, et al. Biochemical constituent, enzyme inhibitory activity, and molecular docking analysis of an endemic plant species, Thymus migricus. Chem Pap. 2021;75:1133–46. https://doi.org/10.1007/s11696-020-01375-z.
Güller P. The in vitro and in silico inhibition mechanism of glutathione reductase by resorcinol derivatives: a molecular docking study. J Mol Struct. 2021;1228:129790. https://doi.org/10.1016/j.molstruc.2020.129790.
Zhang MZ, Chen Q, Yang GF. A review on recent developments of indole-containing antiviral agents. Eur J Med Chem. 2015;89:421–41. https://doi.org/10.1016/j.ejmech.2014.10.065.
CAS Article PubMed Google Scholar
Kanwal KKM, Chigurupati S, Ali F, Younus M, Aldubayan M, Perveen S. Indole-3-acetamides: as potential antihyperglycemic and antioxidant agents; synthesis, in vitro α-amylase inhibitory activity, structure–activity relationship, and in silico studies. ACS Omega. 2021;6:2264–75. https://doi.org/10.1021/acsomega.0c05581.
CAS Article PubMed PubMed Central Google Scholar
Sravanthi TV, Manju SL. Indoles-A promising scaffold for drug development. Eur J Pharm Sci. 2016;91:1–10. https://doi.org/10.1016/j.ejps.2016.05.025.
CAS Article PubMed Google Scholar
Fraczek T, Siwek A, Paneth P. Assessing molecular docking tools for relative biological activity prediction: a case study of Triazole HIV-1 NNRTIs. J Chem Inf Model. 2013;53:3326–42. https://doi.org/10.1021/ci400427a.
CAS Article PubMed Google Scholar
Cetin A. In silico studies on stilbenolignan analogues as SARS-CoV-2 Mpro inhibitors. Chem Phys Lett. 2021;771:138563. https://doi.org/10.1016/j.cplett.2021.138563.
CAS Article PubMed PubMed Central Google Scholar
Schmidt AM, Eilbracht P. Tandem hydroformylation-hydrazone formation-Fischer indole synthesis: a novel approach to tryptamides. Org Biomol Chem. 2005;3:2333–43. https://doi.org/10.1039/B503396A.
CAS Article PubMed Google Scholar
Ellman GL, Courtney KD, Andres V Jr, Featherstone RM. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharm. 1961;7:88–95.
Habig WH, Pabst MJ, Jakoby WB. J Biol Chem. 1974;249:7130–39. https://doi.org/10.1016/S0021-9258(19)42083-8.
CAS Article PubMed Google Scholar
Bhakta HK, Park CH, Yokozawa T, Min BS, Jung HA, Choi JS. Kinetics and molecular docking studies of loganin, morroniside and 7-O-galloyl-d-sedoheptulose derived from Corni fructus as cholinesterase and
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