IL-17A promotes Helicobacter pylori-induced gastric carcinogenesis via interactions with IL-17RC

Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136(5):E359–86.

CAS  PubMed  Article  Google Scholar 

Jung K-W, Won Y-J, Hong S, Kong H-J, Lee ES. Prediction of cancer incidence and mortality in Korea, 2020. Cancer Res Treat. 2020;52(2):351.

PubMed  PubMed Central  Article  Google Scholar 

Watari J, Chen N, Amenta PS, Fukui H, Oshima T, Tomita T, et al. Helicobacter pylori associated chronic gastritis, clinical syndromes, precancerous lesions, and pathogenesis of gastric cancer development. World J Gastroenterol. 2014;20(18):5461.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Peek RM Jr, Crabtree JE. Helicobacter infection and gastric neoplasia. J Pathol. 2006;208(2):233–48.

CAS  PubMed  Article  Google Scholar 

Holian O, Wahid S, Atten MJ, Attar BM. Inhibition of gastric cancer cell proliferation by resveratrol: role of nitric oxide. Am J Physiol-Gastrointest Liver Physiol. 2002;282(5):G809–16.

CAS  PubMed  Article  Google Scholar 

Handa O, Naito Y, Yoshikawa T. Helicobacter pylori: a ROS-inducing bacterial species in the stomach. Inflammation Res. 2010;59(12):997–1003.

CAS  Article  Google Scholar 

Liou G-Y, Storz P. Reactive oxygen species in cancer. Free Radical Res. 2010;44(5):479–96.

CAS  Article  Google Scholar 

Malagoli D. The evolution of the immune system: conservation and diversification. Cambridge: Academic Press; 2016.

Google Scholar 

Xu S, Cao X. Interleukin-17 and its expanding biological functions. Cell Mol Immunol. 2010;7(3):164–74.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Ciric B, El-behi M, Cabrera R, Zhang G-X, Rostami A. IL-23 drives pathogenic IL-17-producing CD8+ T cells. J Immunol. 2009;182(9):5296–305.

CAS  PubMed  Article  Google Scholar 

Michel M-L, Mendes-da-Cruz D, Keller AC, Lochner M, Schneider E, Dy M, et al. Critical role of ROR-γt in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation. Proc Natl Acad Sci. 2008;105(50):19845–50.

CAS  PubMed  PubMed Central  Article  Google Scholar 

O’Brien RL, Roark CL, Born WK. IL-17-producing γδ T cells. Eur J Immunol. 2009;39(3):662–6.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Adamsson J, Ottsjö LS, Lundin SB, Svennerholm A-M, Raghavan S. Gastric expression of IL-17A and IFNγ in Helicobacter pylori infected individuals is related to symptoms. Cytokine. 2017;99:30–4.

CAS  PubMed  Article  Google Scholar 

Hou C, Yang F. Interleukin-17A gene polymorphism is associated with susceptibility to gastric cancer. Int J Clin Exp Pathol. 2015;8(6):7378.

PubMed  PubMed Central  Google Scholar 

Wang J, Li H, Zhang H, Chen Y, Cao Y, Li R, et al. Intratumoral IL17-producing cells infiltration correlate with antitumor immune contexture and improved response to adjuvant chemotherapy in gastric cancer. Ann Oncol. 2019;30(2):266–73.

CAS  PubMed  Article  Google Scholar 

Wu X, Zeng Z, Xu L, Yu J, Cao Q, Chen M, et al. Increased expression of IL17A in human gastric cancer and its potential roles in gastric carcinogenesis. Tumor Biology. 2014;35(6):5347–56.

CAS  PubMed  Article  Google Scholar 

Liu C, Zhang Y, Zhan J, Zhao Y, Wan Q, Peng H, et al. Interleukin-23A is associated with tumor growth in Helicobacter-pylori-related human gastric cancer. Cancer Cell Int. 2014;14(1):1–9.

Article  CAS  Google Scholar 

Malek-Hosseini Z, Taherinejad M, Malekzadeh M, Ghaderi A, Doroudchi M. IL-17A levels in the sera of patients with gastric cancer show limited elevation. Asian Pac J Cancer Prev. 2015;16(16):7149–53.

PubMed  Article  Google Scholar 

Zhang B, Rong G, Wei H, Zhang M, Bi J, Ma L, et al. The prevalence of Th17 cells in patients with gastric cancer. Biochem Biophys Res Commun. 2008;374(3):533–7.

CAS  PubMed  Article  Google Scholar 

Li S, Cong X, Gao H, Lan X, Li Z, Wang W, et al. Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells. J Exp Clin Cancer Res. 2019;38(1):1–13.

Article  Google Scholar 

Liu N, Jiang F, Ye M, Wang B, Ge D, Chang S. HuR confers IL-17a-induced migration and invasion of gastric cancer cells via upregulation of Snail translation. Cytokine. 2022;153: 155830.

CAS  PubMed  Article  Google Scholar 

Wang Y, Wu H, Wu X, Bian Z, Gao Q. Interleukin 17A promotes gastric cancer invasiveness via NF-κB mediated matrix metalloproteinases 2 and 9 expression. PLoS ONE. 2014;9(6): e96678.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Kwon H-J, Won Y-S, Nam K-T, Yoon Y-D, Jee H, Yoon W-K, et al. Vitamin D3 upregulated protein 1 deficiency promotes N-methyl-N-nitrosourea and Helicobacter pylori-induced gastric carcinogenesis in mice. Gut. 2012;61(1):53–63.

CAS  PubMed  Article  Google Scholar 

Shiomi S, Toriie A, Imamura S, Konishi H, Mitsufuji S, Iwakura Y, et al. IL-17 is involved in Helicobacter pylori-induced gastric inflammatory responses in a mouse model. Helicobacter. 2008;13(6):518–24.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Starnes T, Broxmeyer HE, Robertson MJ, Hromas R. Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis. J Immunol. 2002;169(2):642–6.

CAS  PubMed  Article  Google Scholar 

Butcher LD, den Hartog G, Ernst PB, Crowe SE. Oxidative stress resulting from Helicobacter pylori infection contributes to gastric carcinogenesis. Cell Mol Gastroenterol Hepatol. 2017;3(3):316–22.

PubMed  PubMed Central  Article  Google Scholar 

Aponte PM, Caicedo A. Stemness in cancer: stem cells, cancer stem cells, and their microenvironment. Stem Cells Int. 2017;2017:1–17.

Article  CAS  Google Scholar 

Wang S-S, Jiang J, Liang X-h, Tang Y-l. Links between cancer stem cells and epithelial–mesenchymal transition. Onco Target Ther. 2015;8:2973.

CAS  Google Scholar 

Li X, Bechara R, Zhao J, McGeachy MJ, Gaffen SL. IL-17 receptor–based signaling and implications for disease. Nat Immunol. 2019;20(12):1594–602.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Echizen K, Horiuchi K, Aoki Y, Yamada Y, Minamoto T, Oshima H, et al. NF-κB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells. Oncogene. 2019;38(22):4250–63.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Keates S, Hitti YS, Upton M, Kelly CP. Helicobacter pylori infection activates NF-kappa B in gastric epithelial cells. Gastroenterology. 1997;113(4):1099–109.

CAS  PubMed  Article  Google Scholar 

Brandes RP, Weissmann N, Schröder K. Nox family NADPH oxidases: molecular mechanisms of activation. Free Radical Biol Med. 2014;76:208–26.

CAS  Article  Google Scholar 

Jiang Y, Yang S, Li P, Luo X, Li Z, Hao Y, et al. The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms. Oncogene. 2017;36(9):1256–64.

CAS  PubMed  Article  Google Scholar 

Lotti F, Jarrar AM, Pai RK, Hitomi M, Lathia J, Mace A, et al. Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A. J Exp Med. 2013;210(13):2851–72.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Zhang Q, Liu S, Zhang Q, Xiong Z, Wang AR, Myers L, et al. Interleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment. Prostate. 2014;74(8):869–79.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Otani K, Watanabe T, Tanigawa T, Okazaki H, Yamagami H, Watanabe K, et al. Anti-inflammatory effects of IL-17A on Helicobacter pylori-induced gastritis. Biochem Biophys Res Commun. 2009;382(2):252–8.

CAS  PubMed  Article  Google Scholar 

Delgado-Ramirez Y, Baltazar-Perez I, Martinez Y, Callejas BE, Medina-Andrade I, Olguín JE, et al. STAT1 is required for decreasing accumulation of granulocytic cells via il-17 during initial steps of colitis-associated cancer. Int J Mol Sci. 2021;22(14):7695.

CAS  PubMed  PubMed Central  Article  Google Scholar 

He D, Li H, Yusuf N, Elmets CA, Li J, Mountz JD, et al. IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. J Immunol. 2010;184(5):2281–8.

CAS  PubMed  Article  Google Scholar 

留言 (0)

沒有登入
gif