An intersectional analysis of LncRNAs and mRNAs reveals the potential therapeutic targets of Bi Zhong Xiao Decoction in collagen-induced arthritis rats

Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet. 2016;388(10055):2023–38.

CAS  PubMed  Article  Google Scholar 

Smolen JS, Aletaha D, Barton A, Burmester GR, Emery P, Firestein GS, et al. Rheumatoid arthritis. Nat Rev Dis Primers. 2018;4:18001.

PubMed  Article  Google Scholar 

Smolen JS, Landewé RBM, Bijlsma JWJ, Burmester GR, Dougados M, Kerschbaumer A, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update. Ann Rheum Dis. 2020;79(6):685–99.

CAS  PubMed  Article  Google Scholar 

Qiu J. Traditional medicine: a culture in the balance. Nature. 2007;448(7150):126–8.

CAS  PubMed  Article  Google Scholar 

Moudgil KD, Berman BM. Traditional Chinese medicine: potential for clinical treatment of rheumatoid arthritis. Expert Rev Clin Immunol. 2014;10(7):819–22.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Feng C, Chen R, Wang K, Wen C, Xu Z. Chinese traditional medicine (GuiZhi-ShaoYao-ZhiMu decoction) as an add-on medication to methotrexate for rheumatoid arthritis: a meta-analysis of randomized clinical trials. Ther Adv Chronic Dis. 2021;12:2040622321993438.

CAS  PubMed  PubMed Central  Google Scholar 

Wang Y, Chen S, Du K, Liang C, Wang S, Owusu Boadi E, et al. Traditional herbal medicine: therapeutic potential in rheumatoid arthritis. J Ethnopharmacol. 2021;279:114368.

CAS  PubMed  Article  Google Scholar 

Liao H-H, Livneh H, Chung Y-J, Lin C-H, Lai N-S, Yen H-R, et al. A comparison of the risk of fracture in rheumatoid arthritis patients with and without receiving Chinese herbal medicine. J Multidiscip Healthc. 2021;14:3399–409.

PubMed  PubMed Central  Article  Google Scholar 

Cai M, Ni W-J, Han L, Chen W-D, Peng D-Y. Research progress of therapeutic enzymes and their derivatives: based on herbal medicinal products in rheumatoid arthritis. Front Pharmacol. 2021;12:626342.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Liang QH, Zhang HX, Tang T. The effects of bizhongxiao decotion (BZX) on T-lymphocyte subsets in the peripheral blood of patients with rheumatoid arthritis. Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University. 2001;26(6):534–6.

CAS  PubMed  Google Scholar 

Liang Q, Tang T, Zhang H. Clinical investigation of effects of bizhongxiao decoction (BZX) on rheumatoid arthritis on active phase. Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University. 2000;25(5):449–52.

CAS  PubMed  Google Scholar 

Wang A-Y, Liang Q-H, Luo X, Bao T-C, Li C-Y, Cheng J, et al. Effect of bizhongxiao decotion (bzxd) on some cytokines in plasma of rats with cii-induced rheumatoid arthritis. INT J Biomed Sci. 2005;1(1):53–6.

PubMed  PubMed Central  Google Scholar 

Guo Y-j, Chen J, Xiong X-g, Wu D, Zhu H, Liang Q-h. Effect of Bizhongxiao decoction and its dismantled formulae on IL-1 and TNF levels in collagen-induced arthritis in rat synovial joints. Theor Biol Med Model. 2012;9:47.

PubMed  PubMed Central  Article  Google Scholar 

Wu D, Chen J, Zhu H, Xiong X-G, Liang Q-H, Zhang Y, et al. UPLC-PDA determination of paeoniflorin in rat plasma following the oral administration of radix paeoniae alba and its effects on rats with collagen-induced arthritis. Exp Ther Med. 2014;7(1):209–17.

CAS  PubMed  Article  Google Scholar 

Zhu H, Liang Q-H, Xiong X-G, Chen J, Wu D, Wang Y, et al. Anti-Inflammatory effects of the bioactive compound ferulic acid contained in Oldenlandia diffusa on collagen-induced arthritis in rats. Evid based Complement Alternat Med. 2014;2014:573801.

PubMed  PubMed Central  Google Scholar 

Zhu H, Liang Q-H, Xiong X-G, Wang Y, Zhang Z-H, Sun M-J, et al. Anti-inflammatory effects of p-Coumaric acid, a natural compound of, on arthritis model rats. Evid based Complement Alternat Med. 2018;2018:5198594.

PubMed  PubMed Central  Google Scholar 

Yang S, Xing Z, Liu T, Zhou J, Liang Q, Tang T, et al. Synovial tissue quantitative proteomics analysis reveals paeoniflorin decreases LIFR and ASPN proteins in experimental rheumatoid arthritis. Drug Des Devel Ther. 2018;12:463–73.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Cui H, Liu T, Li P, Yang A, Zhou H, Luo J, et al. An intersectional study of LncRNAs and mRNAs reveals the potential therapeutic targets of buyang huanwu decoction in experimental intracerebral hemorrhage. Cell Physiol Biochem. 2018;46(5):2173–86.

CAS  PubMed  Article  Google Scholar 

Wilhelm BT, Marguerat S, Watt S, Schubert F, Wood V, Goodhead I, et al. Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution. Nature. 2008;453(7199):1239–43.

CAS  PubMed  Article  Google Scholar 

Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 2007;447(7146):799–816.

CAS  PubMed  Article  Google Scholar 

Zhong J, Jiang L, Cheng C, Huang Z, Zhang H, Liu H, et al. Altered expression of long non-coding RNA and mRNA in mouse cortex after traumatic brain injury. Brain Res. 2016;1646:589–600.

CAS  PubMed  Article  Google Scholar 

Ali SA, Peffers MJ, Ormseth MJ, Jurisica I, Kapoor M. The non-coding RNA interactome in joint health and disease. Nat Rev Rheumatol. 2021;17(11):692–705.

CAS  PubMed  Article  Google Scholar 

Mo X-B, Wu L-F, Lu X, Zhu X-W, Xia W, Wang L, et al. Detection of lncRNA-mRNA interaction modules by integrating eQTL with weighted gene co-expression network analysis. Funct Integr Genomics. 2019;19(2):217–25.

CAS  PubMed  Article  Google Scholar 

McDonel P, Guttman M. Approaches for Understanding the Mechanisms of Long Noncoding RNA Regulation of Gene Expression. Cold Spring Harb Perspect Biol. 2019;11(12):a032151.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Zeni PF, Mraz M. LncRNAs in adaptive immunity: role in physiological and pathological conditions. RNA Biol. 2021;18(5):619–32.

CAS  PubMed  Article  Google Scholar 

Guo S, Liu J, Jiang T, Lee D, Wang R, Zhou X, et al. (5R)-5-Hydroxytriptolide (LLDT-8) induces substantial epigenetic mediated immune response network changes in fibroblast-like synoviocytes from rheumatoid arthritis patients. Sci Rep. 2019;9(1):11155.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Miao C, Bai L, Yang Y, Huang J. Dysregulation of lncRNAs in rheumatoid arthritis: biomarkers, pathogenesis and potential therapeutic targets. Front Pharmacol. 2021;12:652751.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Wu H, Chen S, Li A, Shen K, Wang S, Wang S, et al. LncRNA expression profiles in systemic lupus erythematosus and rheumatoid arthritis: emerging biomarkers and therapeutic targets. Front Immunol. 2021;12:792884.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Zhou X, Xie D, Huang J, Lu A, Wang R, Jin Y, et al. Therapeutic effects of (5R)-5-Hydroxytriptolide on fibroblast-like synoviocytes in rheumatoid arthritis lncRNA WAKMAR2/miR-4478/E2F1/p53 Axis. Front Immunol. 2021;12:605616.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Piao X, Zhou J, Xue L. Triptolide decreases rheumatoid arthritis fibroblast-like synoviocyte proliferation, invasion, inflammation and presents a therapeutic effect in collagen-induced arthritis rats via inactivating lncRNA RP11–83J16.1 mediated URI1 and β-catenin signaling. Int Immunopharmacol. 2021;99:108010.

CAS  PubMed  Article  Google Scholar 

Yang K-Y, Chen D-L. Shikonin inhibits inflammatory response in rheumatoid arthritis synovial fibroblasts via lncRNA-NR024118. Evid based Complement Alternat Med. 2015;2015:631737.

PubMed  PubMed Central  Google Scholar 

Tsai C-Y, Hsieh S-C, Liu C-W, Lu C-H, Liao H-T, Chen M-H, et al. The expression of non-coding RNAs and their target molecules in rheumatoid arthritis: a molecular basis for rheumatoid pathogenesis and its potential clinical applications. Int J Mol Sci. 2021;22(11):5689.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Klapproth C, Sen R, Stadler PF, Findeiß S, Fallmann J. Common features in lncRNA annotation and classification: a survey. Noncoding RNA. 2021;7(4):77.

CAS  PubMed  PubMed Central  Google Scholar 

Gudenas BL, Wang L. Gene coexpression networks in human brain developmental transcriptomes implicate the association of long noncoding RNAs with intellectual disability. Bioinform Biol Insights. 2015;9(Suppl 1):21–7.

CAS  PubMed  PubMed Central  Google Scholar 

Qin W, Wang T-H, Xie B-H, Sun Q-Q, Huang H, Zhao B-J, et al. Plasma long non-coding RNA expression profiles in patients with rheumatoid arthritis. Clin Lab. 2019. https://doi.org/10.7754/Clin.Lab.2019.190144.

Article  PubMed  Google Scholar 

Wu L-F, Mo X-B, He J-H, He P, Lu X, Deng H-W, et al. Integrative lncRNA-mRNA co-expression network analysis identifies novel lncRNA E2F3-IT1 for rheumatoid arthritis. Clin Transl Med. 2021;11(2):e325.

CAS  PubMed  PubMed Central  Article 

留言 (0)

沒有登入
gif