The prognostic significance of bundle branch block in acute heart failure: a systematic review and meta-analysis

McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, Burri H, Butler J, Čelutkienė J, Chioncel O, Cleland JGF, Coats AJS, Crespo-Leiro MG, Farmakis D, Gilard M, Heymans S, Hoes AW, Jaarsma T, Jankowska EA, Lainscak M, Lam CSP, Lyon AR, McMurray JJV, Mebazaa A, Mindham R, Muneretto C, Francesco Piepoli M, Price S, Rosano GMC, Ruschitzka F, Kathrine SA (2021) 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 42(48):4901. https://doi.org/10.1093/eurheartj/ehab670

Article  PubMed  Google Scholar 

Butler J, Yang M, Manzi MA, Hess GP, Patel MJ, Rhodes T, Givertz MM (2019) Clinical course of patients with worsening heart failure with reduced ejection fraction. J Am Coll Cardiol 73(8):935–944. https://doi.org/10.1016/j.jacc.2018.11.049

Article  PubMed  Google Scholar 

Kurmani S, Squire I (2017) Acute heart failure: definition, classification and epidemiology. Curr Heart Fail Rep 14(5):385–392. https://doi.org/10.1007/s11897-017-0351-y

CAS  Article  PubMed  PubMed Central  Google Scholar 

Sinnenberg L, Givertz MM (2020) Acute heart failure. Trends Cardiovasc Med 30(2):104–112. https://doi.org/10.1016/j.tcm.2019.03.007

Article  PubMed  Google Scholar 

Miró Ò, López-Díez MP, Cardozo C, Moreno LA, Gil V, Jacob J, Herrero P, Llorens P, Escoda R, Richard F, Alquézar-Arbé A, Masip J, García-Álvarez A, Martín-Sánchez FJ, ICA-SEMES group (2022) Impact of hospital and emergency department structural and organizational characteristics on outcomes of acute heart failure. Rev Esp Cardiol (Engl Ed). 75(1):39–49. https://doi.org/10.1016/j.rec.2020.11.022

Article  PubMed  Google Scholar 

Miró Ò, Aguirre A, Herrero P, Jacob J, Martín-Sánchez FJ, Llorens P (2015) PAPRICA-2 study: role of precipitating factor of an acute heart failure episode on intermediate term prognosis. Med Clin (Barc) 145(9):385–389. https://doi.org/10.1016/j.medcli.2015.01.014

Article  Google Scholar 

Madias JE (2007) The resting electrocardiogram in the management of patients with congestive heart failure: established applications and new insights. Pacing Clin Electrophysiol 30(1):123–128. https://doi.org/10.1111/j.1540-8159.2007.00586.x

Article  PubMed  Google Scholar 

Shenkman HJ, Pampati V, Khandelwal AK, McKinnon J, Nori D, Kaatz S, Sandberg KR, McCullough PA (2002) Congestive heart failure and QRS duration: establishing prognosis study. Chest 122(2):528–534. https://doi.org/10.1378/chest.122.2.528

Article  PubMed  Google Scholar 

Sandhu R, Bahler RC (2004) Prevalence of QRS prolongation in a community hospital cohort of patients with heart failure and its relation to left ventricular systolic dysfunction. Am J Cardiol 93(2):244–246. https://doi.org/10.1016/j.amjcard.2003.09.053

Article  PubMed  Google Scholar 

Kashani A, Barold SS (2005) Significance of QRS complex duration in patients with heart failure. J Am Coll Cardiol 46(12):2183–2192. https://doi.org/10.1016/j.jacc.2005.01.071

Article  PubMed  Google Scholar 

Fabiszak T, Łach P, Ratajczak J, Koziński M, Krupa W, Kubica J (2020) Influence of QRS duration and axis on response to cardiac resynchronization therapy in chronic heart failure with reduced left ventricular ejection fraction: a single center study including patients with left bundle branch block. Cardiol J 27(5):575–582. https://doi.org/10.5603/CJ.a2018.0138

Article  PubMed  PubMed Central  Google Scholar 

Park SJ, On YK, Byeon K, Kim JS, Choi JO, Choi DJ, Ryu KH, Jeon ES (2013) Short- and long-term outcomes depending on electrical dyssynchrony markers in patients presenting with acute heart failure: clinical implication of the first-degree atrioventricular block and QRS prolongation from the Korean Heart Failure registry. Am Heart J 165(1):57-64.e2. https://doi.org/10.1016/j.ahj.2012.10.009

Article  PubMed  Google Scholar 

Breidthardt T, Christ M, Matti M, Schrafl D, Laule K, Noveanu M, Boldanova T, Klima T, Hochholzer W, Perruchoud AP, Mueller C (2007) QRS and QTc interval prolongation in the prediction of long-term mortality of patients with acute destabilised heart failure. Heart 93(9):1093–1097. https://doi.org/10.1136/hrt.2006.102319

CAS  Article  PubMed  PubMed Central  Google Scholar 

Lund LH, Jurga J, Edner M, Benson L, Dahlström U, Linde C, Alehagen U (2013) Prevalence, correlates, and prognostic significance of QRS prolongation in heart failure with reduced and preserved ejection fraction. Eur Heart J 34(7):529–539. https://doi.org/10.1093/eurheartj/ehs305

CAS  Article  PubMed  Google Scholar 

Gouda P, Brown P, Rowe BH, McAlister FA, Ezekowitz JA (2016) Insights into the importance of the electrocardiogram in patients with acute heart failure. Eur J Heart Fail 18(8):1032–1040. https://doi.org/10.1002/ejhf.561

Article  PubMed  Google Scholar 

Harjola VP, Follath F, Nieminen MS, Brutsaert D, Dickstein K, Drexler H, Hochadel M, Komajda M, Lopez-Sendon JL, Ponikowski P, Tavazzi L (2010) Characteristics, outcomes, and predictors of mortality at 3 months and 1 year in patients hospitalized for acute heart failure. Eur J Heart Fail 12(3):239–248. https://doi.org/10.1093/eurjhf/hfq002

Article  PubMed  Google Scholar 

Václavík J, Špinar J, Vindiš D, Vítovec J, Widimský P, Číhalík Č, Linhart A, Málek F, Táborský M, Dušek L, Jarkovský J, Fedorco M, Felšöci M, Miklík R, Pařenica J (2014) ECG in patients with acute heart failure can predict in-hospital and long-term mortality. Intern Emerg Med 9(3):283–291. https://doi.org/10.1007/s11739-012-0862-1

Article  PubMed  Google Scholar 

Baldasseroni S, Opasich C, Gorini M, Lucci D, Marchionni N, Marini M, Campana C, Perini G, Deorsola A, Masotti G, Tavazzi L, Maggioni AP, Italian Network on Congestive Heart Failure Investigators (2002) Left bundle-branch block is associated with increased 1-year sudden and total mortality rate in 5517 outpatients with congestive heart failure: a report from the Italian network on congestive heart failure. Am Heart J 143(3):398–405. https://doi.org/10.1067/mhj.2002.121264

Article  PubMed  Google Scholar 

Baldasseroni S, Gentile A, Gorini M, Marchionni N, Marini M, Masotti G, Porcu M, Maggioni AP, Italian Network on Congestive Heart Failure Investigators (2003) Intraventricular conduction defects in patients with congestive heart failure: left but not right bundle branch block is an independent predictor of prognosis. A report from the Italian Network on Congestive Heart Failure (IN-CHF database). Ital Heart J 4(9):607–613

Article  Google Scholar 

Wang NC, Maggioni AP, Konstam MA, Zannad F, Krasa HB, Burnett JC Jr, Grinfeld L, Swedberg K, Udelson JE, Cook T, Traver B, Zimmer C, Orlandi C, Gheorghiade M, Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study With Tolvaptan (EVEREST) Investigators (2008) Clinical implications of QRS duration in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction. JAMA 299(22):2656–2666. https://doi.org/10.1001/jama.299.22.2656

CAS  Article  PubMed  Google Scholar 

Abdel-Qadir HM, Tu JV, Austin PC, Wang JT, Lee DS (2011) Bundle branch block patterns and long-term outcomes in heart failure. Int J Cardiol 146(2):213–218. https://doi.org/10.1016/j.ijcard.2010.01.012

Article  PubMed  Google Scholar 

Lee JH, Park JJ, Cho Y, Oh IY, Yoo BS, Kim JJ, Kim KH, Kang SM, Baek SH, Jeon ES, Cho MC, Chae SC, Oh BH, Choi DJ (2019) Prognostic implication of ventricular conduction disturbance pattern in hospitalized patients with acute heart failure syndrome. Korean Circ J 49(7):602–611. https://doi.org/10.4070/kcj.2018.0290

CAS  Article  PubMed  PubMed Central  Google Scholar 

Tabrizi F, Englund A, Rosenqvist M, Wallentin L, Stenestrand U (2007) Influence of left bundle branch block on long-term mortality in a population with heart failure. Eur Heart J 28(20):2449–2455. https://doi.org/10.1093/eurheartj/ehm262

Article  PubMed  Google Scholar 

Barsheshet A, Leor J, Goldbourt U, Garty M, Schwartz R, Behar S, Luria D, Eldar M, Glikson M (2008) Effect of bundle branch block patterns on mortality in hospitalized patients with heart failure. Am J Cardiol 101(9):1303–1308. https://doi.org/10.1016/j.amjcard.2007.12.035

Article  PubMed  Google Scholar 

Barsheshet A, Goldenberg I, Garty M, Gottlieb S, Sandach A, Laish-Farkash A, Eldar M, Glikson M (2011) Relation of bundle branch block to long-term (four-year) mortality in hospitalized patients with systolic heart failure. Am J Cardiol 107(4):540–544. https://doi.org/10.1016/j.amjcard.2010.10.007

Article  PubMed  Google Scholar 

Hong SJ, Oh J, Kang SM, Youn JC, Han S, Jeon ES, Cho MC, Kim JJ, Yoo BS, Chae SC, Oh BH, Choi DJ, Lee MM, Ryu KH, KorHF Registry (2012) Clinical implication of right bundle branch block in hospitalized patients with acute heart failure: data from the Korean Heart Failure (KorHF) Registry. Int J Cardiol 157(3):416–418. https://doi.org/10.1016/j.ijcard.2012.03.155

Article  PubMed  Google Scholar 

Dzudie A, Milo O, Edwards C, Cotter G, Davison BA, Damasceno A, Mayosi BM, Mondo C, Ogah O, Ojji D, Sani MU, Sliwa K (2014) Prognostic significance of ECG abnormalities for mortality risk in acute heart failure: insight from the Sub-Saharan Africa Survey of Heart Failure (THESUS-HF). J Card Fail 20(1):45–52. https://doi.org/10.1016/j.cardfail.2013.11.005

Article  PubMed  Google Scholar 

Aguiló O, Trullàs JC, Wussler D, Llorens P, Conde-Martel A, López-Ayala P, Jacob J, Roca-Villanueva B, Gil V, Belkin M, Satué-Bartolomé JÁ, Mueller C, Miró Ò, INVESTIGATORS OF THE EAHFE, RICA AND BASEL-V REGISTRIES (2022) Prevalence, related factors and association of left bundle branch block with prognosis in patients with acute heart failure: a simultaneous analysis in 3 independent cohorts. J Card Fail. https://doi.org/10.1016/j.cardfail.2021.11.022

Article  PubMed  Google Scholar 

Huvelle E, Fay R, Alla F, Cohen Solal A, Mebazaa A, Zannad F (2010) Left bundle branch block and mortality in patients with acute heart failure syndrome: a substudy of the EFICA cohort. Eur J Heart Fail 12(2):156–163. https://doi.org/10.1093/eurjhf/hfp180

Article  PubMed  Google Scholar 

Tolppanen H, Siirila-Waris K, Harjola VP, Marono D, Parenica J, Kreutzinger P, Nieminen T, Pavlusova M, Tarvasmaki T, Twerenbold R, Tolonen J, Miklik R, Nieminen MS, Spinar J, Mueller C, Lassus J (2016) Ventricular conduction abnormalities as predictors of long-term survival in acute de novo and decompensated chronic heart failure. ESC Heart Fail 3(1):35–43. https://doi.org/10.1002/ehf2.12068

Article  PubMed  Google Scholar 

Mueller C, Laule-Kilian K, Klima T, Breidthardt T, Hochholzer W, Perruchoud AP, Christ M (2006) Right bundle branch block and long-term mortality in patients with acute congestive heart failure. J Intern Med 260(5):421–428. https://doi.org/10.1111/j.1365-2796.2006.01703.x

CAS  Article  PubMed  Google Scholar 

Trullàs JC, Aguiló O, Mirò Ó, Díez-Manglano J, Carrera-Izquierdo M, Quesada-Simón MA, Álvarez-Rocha P, Llorens P, González-Franco Á, Montero-Pérez-Barquero M, RICA registry researchers (2022) Prevalence and impact on prognosis of right-bundle branch block in patients with acute heart failure: findings from the RICA registry. Rev Clin Esp (Barc). 222(5):272–280. https://doi.org/10.1016/j.rceng.2021.10.002

Article  PubMed  Google Scholar 

McCullough PA, Hassan SA, Pallekonda V, Sandberg KR, Nori DB, Soman SS, Bhatt S, Hudson MP, Weaver WD (2005) Bundle branch block patterns, age, renal dysfunction, and heart failure mortality. Int J Cardiol 102(2):303–308. https://doi.org/10.1016/j.ijcard.2004.10.008

Article  PubMed  Google Scholar 

留言 (0)

沒有登入
gif