Role of gremlin-1 in the physiopathology of the adipose tissues

Elisabetta GrilloDr. Elisabetta Grillo is Adjunct Professor in Biochemistry and Senior Post-Doctoral Fellow at the University of Brescia, Italy. Her research is focused on understanding the role of soluble molecules/growth factors (i.e. Gremlin-1, VEGFs, FGFs, Irisin) and their receptors in human diseases, including cancer and metabolic disorders. Dr. Grillo has contributed to the characterization of gremlin-1 as a non-canonical ligand of the vascular endothelial growth factor receptor 2 in endothelial cells. Recently, Dr. Grillo has investigated the molecular bases of metabolic disorders, contributing to the development of bio-scaffolds for brown tissue regeneration.

Stefania MitolaProf. Stefania Mitola is Full Professor in Biochemistry at the Department of Molecular and Translational Medicine, University of Brescia, Italy. She has a great experience in physiological and pathological angiogenesis. She contributed to the identification of novel and productive ligand/receptor interactions (Gremlin/VEGFR2, HMGB1/RAGE). She is also interested in metabolic disorders and, during the past years, she was involved in the “SCAFFY” project an EUfunded project focused on the development of bio-scaffolds for the regeneration of brown adipose tissue.

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