Paudel YN, Angelopoulou E, Jones NC, O’Brien TJ, Kwan P, Piperi C, et al. Tau related pathways as a connecting link between epilepsy and Alzheimer’s disease. ACS Chem Neurosci. 2019;10(10):4199–212. https://doi.org/10.1021/acschemneuro.9b00460.
CAS Article PubMed Google Scholar
Friedman D, Honig LS, Scarmeas N. Seizures and epilepsy in Alzheimer’s disease. CNS Neurosci Ther. 2012;18(4):285–94. https://doi.org/10.1111/j.1755-5949.2011.00251.x.
Witt JA, Helmstaedter C. Should cognition be screened in new-onset epilepsies? A study in 247 untreated patients. J Neurol. 2012;259(8):1727–31. https://doi.org/10.1007/s00415-012-6526-2.
Rudzinski LA, Meador KJ. Epilepsy and neuropsychological comorbidities. Continuum (Minneap Minn). 2013;19(3 Epilepsy):682–96. https://doi.org/10.1212/01.CON.0000431382.06438.cd.
• Helmstaedter C, Sadat-Hossieny Z, Kanner AM, Meador KJ. Cognitive disorders in epilepsy II: Clinical targets, indications and selection of test instruments. Seizure. 2020;83:223-31. https://doi.org/10.1016/j.seizure.2020.09.031. Current review that details the pro and cons of best practice neuropsychological testing.
Witt JA, Werhahn KJ, Kramer G, Ruckes C, Trinka E, Helmstaedter C. Cognitive-behavioral screening in elderly patients with new-onset epilepsy before treatment. Acta Neurol Scand. 2014;130(3):172–7. https://doi.org/10.1111/ane.12260.
Johnson EL, Krauss GL, Kucharska-Newton A, Albert MS, Brandt J, Walker KA, et al. Dementia in late-onset epilepsy: the Atherosclerosis Risk in Communities study. Neurology. 2020;95(24):e3248–56. https://doi.org/10.1212/WNL.0000000000011080.
CAS Article PubMed PubMed Central Google Scholar
DiFrancesco JC, Tremolizzo L, Polonia V, Giussani G, Bianchi E, Franchi C, et al. Adult-onset epilepsy in presymptomatic Alzheimer’s disease: a retrospective study. J Alzheimers Dis. 2017;60(4):1267–74. https://doi.org/10.3233/JAD-170392.
CAS Article PubMed Google Scholar
Mahamud Z, Mononen CP, Brigo F, Garcia-Ptacek S, Zelano J. Risk of epilepsy diagnosis after a first unprovoked seizure in dementia. Seizure. 2020;82:118–24. https://doi.org/10.1016/j.seizure.2020.09.001.
Beghi E, Beghi M. Epilepsy, antiepileptic drugs and dementia. Curr Opin Neurol. 2020;33(2):191–7. https://doi.org/10.1097/WCO.0000000000000802.
• Stefanidou M, Beiser AS, Himali JJ, Peng TJ, Devinsky O, Seshadri S, et al. Bi-directional association between epilepsy and dementia: The Framingham Heart Study. Neurology. 2020;95(24):e3241-e7. https://doi.org/10.1212/WNL.0000000000011077. Study highlighting the bidirectional association between epilepsy and cognitive dysfunction.
Schnier C, Duncan S, Wilkinson T, Mbizvo GK, Chin RFM. A nationwide, retrospective, data-linkage, cohort study of epilepsy and incident dementia. Neurology. 2020;95(12):e1686–93. https://doi.org/10.1212/WNL.0000000000010358.
Tsai ZR, Zhang HW, Tseng CH, Peng HC, Kok VC, Li GP, et al. Late-onset epilepsy and subsequent increased risk of dementia. Aging (Albany NY). 2021;13(3):3573–87. https://doi.org/10.18632/aging.202299.
Adan G, Mitchell JW, Ziso B, Larner AJ. Diagnosis and management of seizures in neurodegenerative diseases. Current Treatment Options in Neurology. 2021;23(1).
Kanner AM, Helmstaedter C, Sadat-Hossieny Z, Meador K. Cognitive disorders in epilepsy I: Clinical experience, real-world evidence and recommendations. Seizure. 2020;83:216–22. https://doi.org/10.1016/j.seizure.2020.10.009.
Baker J, Libretto T, Henley W, Zeman A. The prevalence and clinical features of epileptic seizures in a memory clinic population. Seizure. 2019;71:83–92. https://doi.org/10.1016/j.seizure.2019.06.016.
Ramsay RE, Rowan AJ, Pryor FM. Special considerations in treating the elderly patient with epilepsy. Neurology. 2004;62(5 Suppl 2):S24–9. https://doi.org/10.1212/wnl.62.5_suppl_2.s24.
Vossel KA, Tartaglia MC, Nygaard HB, Zeman AZ, Miller BL. Epileptic activity in Alzheimer’s disease: causes and clinical relevance. Lancet Neurol. 2017;16(4):311–22. https://doi.org/10.1016/S1474-4422(17)30044-3.
Article PubMed PubMed Central Google Scholar
Witt JA, Helmstaedter C. Cognition in the early stages of adult epilepsy. Seizure. 2015;26:65–8. https://doi.org/10.1016/j.seizure.2015.01.018.
Tolchin B, Lee JW, Pavlova M, Dworetzky BA, Sarkis RA. Diagnostic yield of ambulatory EEGs in the elderly. Clin Neurophysiol. 2017;128(7):1350–3. https://doi.org/10.1016/j.clinph.2017.01.005.
Forooghifar F, Aminifar A, Cammoun L, Wisniewski I, Ciumas C, Ryvlin P, et al. A self-aware epilepsy monitoring system for real-time epileptic seizure detection. Mobile Networks and Applications. 2019. https://doi.org/10.1007/s11036-019-01322-7.
Krumholz A, Wiebe S, Gronseth G, Shinnar S, Levisohn P, Ting T, et al. Practice Parameter: evaluating an apparent unprovoked first seizure in adults (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2007;69(21):1996–2007. https://doi.org/10.1212/01.wnl.0000285084.93652.43.
CAS Article PubMed Google Scholar
Sinha S, Satishchandra P, Kalband BR, Bharath RD, Thennarasu K. Neuroimaging observations in a cohort of elderly manifesting with new onset seizures: experience from a university hospital. Ann Indian Acad Neurol. 2012;15(4):273–80. https://doi.org/10.4103/0972-2327.104335.
Article PubMed PubMed Central Google Scholar
Semple BD, Zamani A, Rayner G, Shultz SR, Jones NC. Affective, neurocognitive and psychosocial disorders associated with traumatic brain injury and post-traumatic epilepsy. Neurobiol Dis. 2019;123:27–41. https://doi.org/10.1016/j.nbd.2018.07.018.
Willment K, Hill M, Baslet G, Loring DW. Cognitive impairment and evaluation in psychogenic nonepileptic seizures: an integrated cognitive-emotional approach. Clin EEG Neurosci. 2015;46(1):42–53. https://doi.org/10.1177/1550059414566881.
Patel AD, Baca C, Franklin G, Herman ST, Hughes I, Meunier L, et al. Quality improvement in neurology: Epilepsy Quality Measurement Set 2017 update. Neurology. 2018;91(18):829–36. https://doi.org/10.1212/WNL.0000000000006425.
American Psychological Association. Clinical practice guideline for the treatment of depression across three age cohorts. American Psychological Association Guideline Development Panel for the Treatment of Depressive Disorders. 2019.
The Management of Major Depressive Disorder Working Group. VA/DOD clinical practice guidline for the management of major depressive disorder In: Department of Veterans Affairs, editor. 2016.
Leppik IE, Birnbaum AK. Epilepsy in the elderly. Ann N Y Acad Sci. 2010;1184:208–24. https://doi.org/10.1111/j.1749-6632.2009.05113.x.
CAS Article PubMed PubMed Central Google Scholar
Seo JG, Cho YW, Kim KT, Kim DW, Yang KI, Lee ST, et al. Pharmacological treatment of epilepsy in elderly patients. J Clin Neurol. 2020;16(4):556–61. https://doi.org/10.3988/jcn.2020.16.4.556.
Article PubMed PubMed Central Google Scholar
Cumbo E, Ligori LD. Levetiracetam, lamotrigine, and phenobarbital in patients with epileptic seizures and Alzheimer’s disease. Epilepsy Behav. 2010;17(4):461–6. https://doi.org/10.1016/j.yebeh.2010.01.015.
Barr WB. Understanding the cognitive side effects of antiepileptic drugs: can functional imaging be helpful? Epilepsy Curr. 2019;19(1):22–3. https://doi.org/10.1177/1535759718822032.
Article PubMed PubMed Central Google Scholar
Rowan AJ, Ramsay RE, Collins JF, Pryor F, Boardman KD, Uthman BM, et al. New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. Neurology. 2005;64(11):1868–73. https://doi.org/10.1212/01.WNL.0000167384.68207.3E.
CAS Article PubMed Google Scholar
Liu A, Bryant A, Jefferson A, Friedman D, Minhas P, Barnard S, et al. Exploring the efficacy of a 5-day course of transcranial direct current stimulation (TDCS) on depression and memory function in patients with well-controlled temporal lobe epilepsy. Epilepsy Behav. 2016;55:11–20. https://doi.org/10.1016/j.yebeh.2015.10.032.
Lattanzi S, Trinka E, Del Giovane C, Nardone R, Silvestrini M, Brigo F. Antiepileptic drug monotherapy for epilepsy in the elderly: a systematic review and network meta-analysis. Epilepsia. 2019;60(11):2245–54. https://doi.org/10.1111/epi.16366.
Zhao L, Wu YP, Qi JL, Liu YQ, Zhang K, Li WL. Efficacy of levetiracetam compared with phenytoin in prevention of seizures in brain injured patients: a meta-analysis. Medicine (Baltimore). 2018;97(48): e13247. https://doi.org/10.1097/MD.0000000000013247.
Tekin S, Aykut-Bingol C, Tanridag T, Aktan S. Antiglutamatergic therapy in Alzheimer’s disease–effects of lamotrigine. Short communication J Neural Transm (Vienna). 1998;105(2–3):295–303. https://doi.org/10.1007/s007020050059.
• Cretin B. Treatment of seizures in older patients with dementia. Drugs Aging. 2020. https://doi.org/10.1007/s40266-020-00826-2. Extenstive review of best practice pharmacology for this patient population.
Bruun E, Kalviainen R, Keranen T. Outcome of initial antiepileptic drug treatment in elderly patients with newly diagnosed epilepsy. Epilepsy Res. 2016;127:60–5. https://doi.org/10.1016/j.eplepsyres.2016.08.023.
CAS Article PubMed Google Scholar
Desbeaumes Jodoin V, Richer F, Miron JP, Fournier-Gosselin MP, Lesperance P. Long-term sustained cognitive benefits of vagus nerve stimulation in refractory depression. J ECT. 2018;34(4):283–90. https://doi.org/10.1097/YCT.0000000000000502.
Panebianco M, Zavanone C, Dupont S, Restivo DA, Pavone A. Vagus nerve stimulation therapy in partial epilepsy: a review. Acta Neurol Belg. 2016;116(3):241–8. https://doi.org/10.1007/s13760-016-0616-3.
Raspin C, Shankar R, Barion F, Pollit V, Murphy J, Sawyer L, et al. An economic evaluation of vagus nerve stimulation as an adjunctive treatment to anti-seizure medications for the treatment of drug-resistant epilepsy in England. J Med Econ. 2021;24(1):1037–51. https://doi.org/10.1080/13696998.2021.1964306.
Skarpaas TL, Jarosiewicz B, Morrell MJ. Brain-responsive neurostimulation for epilepsy (RNS((R)) System). Epilepsy Res. 2019;153:68–70. https://doi.org/10.1016/j.eplepsyres.2019.02.003.
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