Serum level of total histone 3, H3K4me3, and H3K27ac after non-emergent cardiac surgery suggests the persistence of smoldering inflammation at 3 months in an adult population

Day JR, Taylor KM. The systemic inflammatory response syndrome and cardiopulmonary bypass. Int J Surg. 2005;3:129–40.

CAS  PubMed  Article  Google Scholar 

Giacinto O, Satriano U, Nenna A, Spadaccio C, Lusini M, Mastroianni C, Nappi F, Chello M. Inflammatory response and endothelial dysfunction following cardiopulmonary bypass: pathophysiology and pharmacological targets. Recent Pat Inflamm Allergy Drug Discov. 2019;13:158–73.

CAS  PubMed  Article  Google Scholar 

Ruifrok WT, Westenbrink BD, de Boer RA, den Hamer IJ, Erasmus ME, Mungroop HE, Epema AH, Voors AA, van Veldhuisen DJ, van Gilst WH. Apoptosis during CABG surgery with the use of cardiopulmonary bypass is prominent in ventricular but not in atrial myocardium. Neth Heart J. 2010;18:236–42.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Squiccimarro E, Stasi A, Lorusso R, Paparella D: Narrative review of the systemic inflammatory reaction to cardiac surgery and cardiopulmonary bypass. Artif Organs; n/a

Wen Z, Lei Z, Yao L, Jiang P, Gu T, Ren F, Liu Y, Gou C, Li X, Wen T. Circulating histones are major mediators of systemic inflammation and cellular injury in patients with acute liver failure. Cell Death Dis. 2016;7:e2391–e2391.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Shaw RJ, Austin J, Taylor J, Dutt T, Wang G, Abrams ST, Toh CH. Circulating histone levels correlate with the severity of COVID-19 and the extent of coagulation activation and inflammation. Blood. 2020;136:19–19.

Article  Google Scholar 

Yokoyama Y, Ito T, Yasuda T, Furubeppu H, Kamikokuryo C, Yamada S, Maruyama I, Kakihana Y. Circulating histone H3 levels in septic patients are associated with coagulopathy, multiple organ failure, and death: a single-center observational study. Thromb J. 2019;17:1.

PubMed  PubMed Central  Article  Google Scholar 

Abrams ST, Zhang N, Manson J, Liu T, Dart C, Baluwa F, Wang SS, Brohi K, Kipar A, Yu W, Wang G, Toh CH. Circulating histones are mediators of trauma-associated lung injury. Am J Respir Crit Care Med. 2013;187:160–9.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Alhamdi Y, Abrams ST, Cheng Z, Jing S, Su D, Liu Z, Lane S, Welters I, Wang G, Toh C-H. Circulating histones are major mediators of cardiac injury in patients with sepsis*. Crit Care Med. 2015;43:2094–103.

CAS  PubMed  Article  Google Scholar 

Liu T, Huang W, Szatmary P, Abrams ST, Alhamdi Y, Lin Z, Greenhalf W, Wang G, Sutton R, Toh CH. Accuracy of circulating histones in predicting persistent organ failure and mortality in patients with acute pancreatitis. Br J Surg. 2017;104:1215–25.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Xu J, Zhang X, Pelayo R, Monestier M, Ammollo CT, Semeraro F, Taylor FB, Esmon NL, Lupu F, Esmon CT. Extracellular histones are major mediators of death in sepsis. Nat Med. 2009;15:1318–21.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Chew Michelle S, Brandslund I, Brix-Christensen V, Ravn Hanne B, Hjortdal Vibeke E, Pedersen J, Hjortholm K, Hansen Ole K, Tønnesen E. Tissue injury and the inflammatory response to pediatric cardiac surgery with cardiopulmonary bypass: a descriptive study. Anesthesiology. 2001;94:745–53.

Article  Google Scholar 

Xu J, Zhang X, Monestier M, Esmon NL, Esmon CT. Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury. J Immunol. 2011;187:2626–31.

CAS  PubMed  Article  Google Scholar 

Nowill AE, Fornazin MC, Spago MC, Dorgan Neto V, Pinheiro VRP, Alexandre SSS, Moraes EO, Souza G, Eberlin MN, Marques LA, Meurer EC, Franchi GC Jr, de Campos-Lima PO. Immune response resetting in ongoing sepsis. J Immunol. 2019;203:1298–312.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Dominguez-Andres J, Netea MG. Long-term reprogramming of the innate immune system. J Leukoc Biol. 2019;105:329–38.

CAS  PubMed  Article  Google Scholar 

Fink R, Al-Obaidi M, Grewal S, Winter M, Pepper J. Monocyte activation markers during cardiopulmonary bypass. Perfusion. 2003;18:83–6.

CAS  PubMed  Article  Google Scholar 

Flier S, Concepcion AN, Versteeg D, Kappen TH, Hoefer IE, de Lange DW, Pasterkamp G, Buhre WF. Monocyte hyporesponsiveness and Toll-like receptor expression profiles in coronary artery bypass grafting and its clinical implications for postoperative inflammatory response and pneumonia: an observational cohort study. Eur J Anaesthesiol. 2015;32:177–88.

CAS  PubMed  Article  Google Scholar 

Reschke C. Epigenetic regulation of cytokine production in endotoxin tolerance. Medicine. Berlin: Humbol University; 2016.

Google Scholar 

Pena OM, Hancock DG, Lyle NH, Linder A, Russell JA, Xia J, Fjell CD, Boyd JH, Hancock RE. An endotoxin tolerance signature predicts sepsis and organ dysfunction at initial clinical presentation. EBioMedicine. 2014;1:64–71.

PubMed  PubMed Central  Article  Google Scholar 

Xiao LI, Cao Y, Wang Y, Lai X, Gao K-Q, Du P, Zhang B-K, Jia S-J. Aberrant histone modifications of global histone and MCP-1 promoter in CD14+ monocytes from patients with coronary artery disease. Die Pharmazie Int J Pharm Sci. 2018;73:202–6.

CAS  Google Scholar 

Szerafin T, Hoetzenecker K, Hacker S, Horvath A, Pollreisz A, Árpád P, Mangold A, Wliszczak T, Dworschak M, Seitelberger R, Wolner E, Ankersmit HJ. Heat shock proteins 27, 60, 70, 90α, and 20S proteasome in on-pump versus off-pump coronary artery bypass graft patients. Ann Thorac Surg. 2008;85:80–7.

PubMed  Article  Google Scholar 

Schafler A, Kirmanoglou K, Gallmeier U, Pecher P. Heat shock protein 60 expression in patients undergoing cardiac operations. J Cardiovasc Surg. 2003;44:187.

CAS  Google Scholar 

Gao H, Zhang N, Lu F, Yu X, Zhu L, Mo X, Wang W. Circulating histones for predicting prognosis after cardiac surgery: a prospective study. Interact Cardiovasc Thorac Surg. 2016;23:681–7.

PubMed  Article  Google Scholar 

Wehlin L, Vedin J, Vaage J, Lundahl J. Peripheral blood monocyte activation during coronary artery bypass grafting with or without cardiopulmonary bypass. Scand Cardiovasc J. 2005;39:78–86.

PubMed  Article  Google Scholar 

Cao Y, Lu L, Liu M, Li XC, Sun RR, Zheng Y, Zhang PY. Impact of epigenetics in the management of cardiovascular disease: a review. Eur Rev Med Pharmacol Sci. 2014;18:3097–104.

CAS  PubMed  Google Scholar 

Liu Y, Reynolds LM, Ding J, Hou L, Lohman K, Young T, Cui W, Huang Z, Grenier C, Wan M, Stunnenberg HG, Siscovick D, Hou L, Psaty BM, Rich SS, Rotter JI, Kaufman JD, Burke GL, Murphy S, Jacobs DR, Post W, Hoeschele I, Bell DA, Herrington D, Parks JS, Tracy RP, McCall CE, Stein JH. Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis. Nat Commun. 2017;8:393.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Kapellos TS, Bonaguro L, Gemund I, Reusch N, Saglam A, Hinkley ER, Schultze JL. Human monocyte subsets and phenotypes in major chronic inflammatory diseases. Front Immunol. 2019;10:2035.

CAS  PubMed  PubMed Central  Article  Google Scholar 

McEwen BS. Biomarkers for assessing population and individual health and disease related to stress and adaptation. Metabolism. 2015;64:S2–10.

CAS  PubMed  Article  Google Scholar 

Csoka AB, Szyf M. Epigenetic side-effects of common pharmaceuticals: a potential new field in medicine and pharmacology. Med Hypotheses. 2009;73:770–80.

CAS  PubMed  Article  Google Scholar 

Lötsch J, Schneider G, Reker D, Parnham MJ, Schneider P, Geisslinger G, Doehring A. Common non-epigenetic drugs as epigenetic modulators. Trends Mol Med. 2013;19:742–53.

PubMed  Article  CAS  Google Scholar 

Addo KA, Bulka C, Dhingra R, Santos HP Jr, Smeester L, O’Shea TM, Fry RC. Acetaminophen use during pregnancy and DNA methylation in the placenta of the extremely low gestational age newborn (ELGAN) cohort. Environ Epigenetics. 2019. https://doi.org/10.1093/eep/dvz010.

Article  Google Scholar 

Nikpay M, Stewart AFR, McPherson R. Partitioning the heritability of coronary artery disease highlights the importance of immune-mediated processes and epigenetic sites associated with transcriptional activity. Cardiovasc Res. 2017;113:973–83.

CAS  PubMed  Article  Google Scholar 

Lim PS, Li J, Holloway AF, Rao S. Epigenetic regulation of inducible gene expression in the immune system. Immunology. 2013;139:285–93.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Hall AW, Chaffin M, Roselli C, Lin H, Lubitz SA, Bianchi V, Geeven G, Bedi K, Margulies KB, de Laat W, Tucker NR, Ellinor PT. Epigenetic analyses of human left atrial tissue identifies gene networks underlying atrial fibrillation. Circ Genom Precis Med. 2020;13: e003085.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Chaaban H, Keshari RS, Silasi-Mansat R, Popescu NI, Mehta-D’Souza P, Lim YP, Lupu F. Inter-α inhibitor protein and its associated glycosaminoglycans protect against histone-induced injury. Blood. 2015;125:2286–96.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Zhang Y, Haeger SM, Yang Y, Dailey KL, Ford JA, Schmidt EP. Circulating heparan sulfate fragments attenuate histone-induced lung injury independently of histone binding. Shock. 2017;48:666–73.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Nagano F, Mizuno T, Mizumoto S, Yoshioka K, Takahashi K, Tsuboi N, Maruyama S, Yamada S, Nagamatsu T. Chondroitin sulfate protects vascular endothelial cells from toxicities of extracellular histones. Eur J Pharmacol. 2018;826:48–55.

CAS 

留言 (0)

沒有登入
gif