Exploring the Relationship Between Endogenous Pain Modulation, Pain Intensity, and Depression in Patients Using Opioids for Chronic Low Back Pain

*Department of Anesthesiology, Perioperative & Pain Medicine, Harvard Medical School, Brigham & Women’s Hospital

†Departments of Family and Community Medicine

‡Public Health Sciences

§Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Hershey, PA

∥Center on Mindfulness and Integrative Health Intervention Development

¶College of Social Work, University of Utah, Salt Lake City, UT

Supported through a Patient-Centered Outcomes Research Institute (PCORI) Award (OPD-1601-33860). The views and statements in this publication are solely the responsibility of the authors and do not necessarily represent the views of the PCORI, its Board of Governors or Methodology Committee. This project also received funding and institutional support through University of Wisconsin- Madison School of Medicine and Public Health, and its Department of Family Medicine and Community Health; Brigham and Women’s Hospital, Harvard Medical School; University of Utah College of Social Work; and Pennsylvania State University Department of Family and Community Medicine. The remaining authors declare no conflict of interest.

Reprints: Asimina Lazaridou, PhD, Brigham & Women’s Hospital, Pain Management Center, 850 Boylston Street, Chestnut Hill, MA 02467 (e-mail: [email protected]).

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