The clinical implications of pre-liver transplant diabetes on post-liver transplant outcomes in patients with NASH: analysis of the UNOS database

Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease-meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64(1):73–84

Article  Google Scholar 

Khan RS, Bril F, Cusi K, Newsome PN. Modulation of insulin resistance in nonalcoholic fatty liver disease. Hepatology. 2019;70(2):711–724

CAS  PubMed  Google Scholar 

Kumashiro N, Erion DM, Zhang D, et al. Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease. Proc Natl Acad Sci USA. 2011;108(39):16381–16385

CAS  Article  Google Scholar 

Wree A, Schlattjan M, Bechmann LP, et al. Adipocyte cell size, free fatty acids and apolipoproteins are associated with non-alcoholic liver injury progression in severely obese patients. Metabolism. 2014;63(12):1542–1552

CAS  Article  Google Scholar 

Haflidadottir S, Jonasson JG, Norland H, et al. Long-term follow-up and liver-related death rate in patients with non-alcoholic and alcoholic related fatty liver disease. BMC Gastroenterol. 2014;14:166

Article  Google Scholar 

Wong RJ, Aguilar M, Cheung R, et al. Nonalcoholic steatohepatitis is the second leading etiology of liver disease among adults awaiting liver transplantation in the United States. Gastroenterology. 2015;148(3):547–555

Article  Google Scholar 

Merion RM, Schaubel DE, Dykstra DM, Freeman RB, Port FK, Wolfe RA. The survival benefit of liver transplantation. Am J Transpl. 2005;5(2):307–313

Article  Google Scholar 

Tsai MS, Wang YC, Wang HH, Lee PH, Jeng LB, Kao CH. Pre-existing diabetes and risks of morbidity and mortality after liver transplantation: a nationwide database study in an Asian population. Eur J Intern Med. 2015;26(6):433–438

Article  Google Scholar 

Hoehn RS, Singhal A, Wima K, et al. Effect of pretransplant diabetes on short-term outcomes after liver transplantation: a national cohort study. Liver Int. 2015;35(7):1902–1909

Article  Google Scholar 

Sarwar N, Gao P, Emerging Risk Factors Collaboration, et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 2010;375(9733):2215–2222

CAS  Article  Google Scholar 

Anand SS, Dagenais GR, Mohan V, et al. Glucose levels are associated with cardiovascular disease and death in an international cohort of normal glycaemic and dysglycaemic men and women: the EpiDREAM cohort study. Eur J Prev Cardiol. 2012;19(4):755–764

CAS  Article  Google Scholar 

Steggerda JA, Kim IK, Todo T, Malinoski D, Klein AS, Bloom MB. Liver Transplant survival index for patients with model for end-stage liver disease score ≥ 35: modeling risk and adjusting expectations in the share 35 era. J Am Coll Surg. 2019;228(4):437-450.e8

Article  Google Scholar 

Xing M, Kim HS. Independent prognostic factors for posttransplant survival in hepatocellular carcinoma patients undergoing liver transplantation. Cancer Med. 2017;6(1):26–35

CAS  Article  Google Scholar 

Austin PC, Steyerberg EW, Putter H. Fine-Gray subdistribution hazard models to simultaneously estimate the absolute risk of different event types: cumulative total failure probability may exceed 1. Stat Med. 2021;40(19):4200–4212

Article  Google Scholar 

Zhang Z. Multiple imputation with multivariate imputation by chained equation (MICE) package. Ann Transl Med. 2016;4(2):30

PubMed  PubMed Central  Google Scholar 

Samuelson AL, Lee M, Kamal A, Keeffe EB, Ahmed A. Diabetes mellitus increases the risk of mortality following liver transplantation independent of MELD score. Dig Dis Sci. 2010;55(7):2089–2094

Article  Google Scholar 

Volk ML, Hernandez JC, Lok AS, Marrero JA. Modified Charlson comorbidity index for predicting survival after liver transplantation. Liver Transpl. 2007;13(11):1515–1520

Article  Google Scholar 

Vollmar B, Menger MD. The hepatic microcirculation: mechanistic contributions and therapeutic targets in liver injury and repair. Physiol Rev. 2009;89(4):1269–1339

CAS  Article  Google Scholar 

Palladino R, Tabak AG, Khunti K, et al. Association between pre-diabetes and microvascular and macrovascular disease in newly diagnosed type 2 diabetes. BMJ Open Diabetes Res Care. 2020;8(1):e001061

Article  Google Scholar 

Alfonso AR, Kantar RS, Ramly EP, et al. Diabetes is associated with an increased risk of wound complications and readmission in patients with surgically managed pressure ulcers. Wound Repair Regen. 2019;27(3):249–256

Article  Google Scholar 

Dokken BB. The pathophysiology of cardiovascular disease and diabetes: beyond blood pressure and lipids. Diabetes Spectr. 2008;21(3):160–165

Article  Google Scholar 

Patel KL. Impact of tight glucose control on postoperative infection rates and wound healing in cardiac surgery patients. J Wound Ostomy Continence Nurs. 2008;35(4):397–404 (quiz 405-406)

Article  Google Scholar 

Roccaro GA, Goldberg DS, Hwang WT, et al. Sustained posttransplantation diabetes is associated with long-term major cardiovascular events following liver transplantation. Am J Transpl. 2018;18(1):207–215

CAS  Article  Google Scholar 

Alicic RZ, Rooney MT, Tuttle KR. Diabetic kidney disease: challenges, progress, and possibilities. Clin J Am Soc Nephrol. 2017;12(12):2032–2045

CAS  Article  Google Scholar 

Pálsson R, Patel UD. Cardiovascular complications of diabetic kidney disease. Adv Chronic Kidney Dis. 2014;21(3):273–280

Article  Google Scholar 

Campbell MS, Kotlyar DS, Brensinger CM, et al. Renal function after orthotopic liver transplantation is predicted by duration of pretransplantation creatinine elevation. Liver Transpl. 2005;11(9):1048–1055

Article  Google Scholar 

Price CL, Hassi HOSA, English NR, Blakemore AIF, Stagg AJ, Knight SC. Methylglyoxal modulates immune responses: relevance to diabetes. J Cell Mol Med. 2010;14(6B):1806–1815

CAS  Article  Google Scholar 

Berbudi A, Rahmadika N, Tjahjadi AI, Ruslami R. Type 2 diabetes and its impact on the immune system. Curr Diabetes Rev. 2020;16(5):442–449

PubMed  PubMed Central  Google Scholar 

Daryabor G, Atashzar MR, Kabelitz D, Meri S, Kalantar K. The effects of type 2 diabetes mellitus on organ metabolism and the immune system. Front Immunol. 2020;11:1582

CAS  Article  Google Scholar 

Wallia A, Schmidt K, Oakes DJ, et al. Glycemic control reduces infections in post-liver transplant patients: results of a prospective randomized study. J Clin Endocrinol Metab. 2017;102(2):451–459

PubMed  Google Scholar 

Ye C, Saincher M, Tandon P, et al. Cardiac work-up protocol for liver transplant candidates: experience from a single liver transplant centre. Can J Gastroenterol. 2012;26(11):806–810

Article  Google Scholar 

Baldwin D Jr, Duffin KE. Rosiglitazone treatment of diabetes mellitus after solid organ transplantation. Transplantation. 2004;77(7):1009–1014

CAS  Article  Google Scholar 

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