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Topic: Cancer, Epidemiology
Category: Original article
MATERIALS AND METHODS: Data for 1220 patients were collected from the processing of files and a pre-established questionnaire. The anthropobiological parameters and the associated treatment type have been unspecified.
RESULTS: Women (OR=17.26; 95% CI=2.88-103.45, p<0.01), overweight individuals (OR=4.81; 95% CI=1.63-14.14, p<0.01) and hypertensive diabetic subjects (OR=3.82; 95% CI=1.39-10.49, p< 0.01) are more exposed to cancers. It is interesting to note that diabetic subjects treated with insulin have a reduced risk of developing cancer (OR=0.22; 95% CI=0.07-0.67, p<0.01). Diabetic subjects treated with metformin have a four and a half times higher risk of developing cancer (OR=4.61; 95% CI=1.48-14.37, p<0.01).
CONCLUSIONS: In type 2 diabetic subjects, cancer is significantly linked to overweight, to the presence of essential hypertension in individuals under hypotensive as well as in patients treated with metformin.
To cite this article Dennouni-Medjati N. Department of Biology, University of Tlemcen, Tlemcen, Algeria , Dali-Sahi M., Guermouche B. Department of Biology, University of Tlemcen, Tlemcen, Algeria , Merad Boudia H. N. Department of Biology, University of Tlemcen, Tlemcen, Algeria , Djelti F. Department of Biology, University of Tlemcen, Tlemcen, Algeria , Harek Y. Analytical Chemistry and Electrochemistry Laboratory, University of Tlemcen, Tlemcen, Algeria , Kachekouche Y. Department of Biology, University of Tlemcen, Tlemcen, Algeria Antidiabetic treatment, obesity, and cancer risk in Algerian patients with type 2 diabetes mellitus WCRJ 2022;
9: e2394
DOI: 10.32113/wcrj_20229_2394
Submission date: 26 May 2022
Revised on: 14 Jul 2022
Accepted on: 30 Aug 2022
Published online: 15 Sep 2022
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