An extracranial CNS presentation of the emerging “intracranial” mesenchymal tumor, FET: CREB-fusion positive

Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D et al (2021) The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro Oncol 23(8):1231–1251

CAS  Article  Google Scholar 

Tauziède-Espariat A, Sievers P, Larousserie F, Benzakoun J, Guillemot D, Pierron G et al (2021) An integrative histopathological and epigenetic characterization of primary intracranial mesenchymal tumors, FET:CREB-fused broadening the spectrum of tumor entities in comparison with their soft tissue counterparts. Brain Pathol Zurich Switz 32:e13010

Google Scholar 

Sloan EA, Gupta R, Koelsche C, Chiang J, Villanueva-Meyer JE, Alexandrescu S et al (2021) Intracranial mesenchymal tumors with FET–CREB fusion are composed of at least two epigenetic subgroups distinct from meningioma and extracranial sarcomas. Brain Pathol Zurich Switz 32:e13037

Google Scholar 

Tauziède-Espariat A, Pierron G, Guillemot D, Sievers P, Cazals-Hatem D, Faillot T et al (2021) A novel SMARCA2-CREM fusion: expanding the molecular spectrum of intracranial mesenchymal tumors beyond the FET genes. Acta Neuropathol Commun 9:174

Article  Google Scholar 

Sloan EA, Chiang J, Villanueva-Meyer JE, Alexandrescu S, Eschbacher JM, Wang W et al (2020) Intracranial mesenchymal tumor with FET–CREB fusion—a unifying diagnosis for the spectrum of intracranial myxoid mesenchymal tumors and angiomatoid fibrous histiocytoma-like neoplasms. Brain Pathol Zurich Switz 31:e12918

Google Scholar 

Hovestadt V, Jones DTW, Picelli S, Wang W, Kool M, Northcott PA et al (2014) Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing. Nature 510:537–541

CAS  Article  Google Scholar 

Kim NR, Kim S-I, Park JW, Park C-K, Chung CK, Choi S-H et al (2022) Brain parenchymal angiomatoid fibrous histiocytoma and spinal myxoid mesenchymal tumor with FET: CREB fusion, a spectrum of the same tumor type. Neuropathology 42(4):257–268

CAS  Article  Google Scholar 

Bale TA, Oviedo A, Kozakewich H, Giannini C, Davineni PK, Ligon K et al (2018) Intracranial myxoid mesenchymal tumors with EWSR1–CREB family gene fusions: myxoid variant of angiomatoid fibrous histiocytoma or novel entity? Brain Pathol Zurich Switz 28:183–191

CAS  Article  Google Scholar 

Ballester LY, Meis JM, Lazar AJ, Prabhu SS, Hoang KB, Leeds NE et al (2020) Intracranial myxoid mesenchymal tumor with EWSR1-ATF1 fusion. J Neuropathol Exp Neurol 79:347–351

CAS  Article  Google Scholar 

De Los SY, Shin D, Malnik S, Rivera-Zengotita M, Tran D, Ghiaseddin A et al (2021) Intracranial myxoid mesenchymal neoplasms with EWSR1 gene rearrangement: report of 2 midline cases with one demonstrating durable response to MET inhibitor monotherapy. Neuro-Oncol Adv 3:vdab016

Article  Google Scholar 

Dunham C (2015) Uncommon pediatric tumors of the posterior fossa: pathologic and molecular features. Childs Nerv Syst 31:1729–1737

CAS  Article  Google Scholar 

Kambe A, Kuwamoto S, Shimizu T, Amisaki H, Sakamoto M, Inagaki H et al (2021) A case of intracranial myxoid mesenchymal tumor with EWSR1:CREM fusion in an adult female: extensive immunohistochemical evaluation. Neuropathology 41:315–323

CAS  Article  Google Scholar 

Kao Y-C, Lan J, Tai H-C, Li C-F, Liu K-W, Tsai J-W et al (2014) Angiomatoid fibrous histiocytoma: clinicopathological and molecular characterisation with emphasis on variant histomorphology. J Clin Pathol 67:210–215

CAS  Article  Google Scholar 

Komatsu M, Yoshida A, Tanaka K, Matsuo K, Sasayama T, Kojita Y et al (2020) Intracranial myxoid mesenchymal tumor with EWSR1-CREB1 gene fusion: a case report and literature review. Brain Tumor Pathol 37:76–80

CAS  Article  Google Scholar 

Konstantinidis A, Cheesman E, O’Sullivan J, Pavaine J, Avula S, Pizer B et al (2019) Intracranial angiomatoid fibrous histiocytoma with EWSR1–CREB family fusions: a report of 2 pediatric cases. World Neurosurg 126:113–119

Article  Google Scholar 

Libbrecht S, Van Der Meulen J, Mondelaers V, Baert E, VandeWalle C, Van Dorpe J et al (2020) Intracranial myxoid mesenchymal tumor with EWSR1-CREB1 fusion. Pathol Res Pract 216:153239

Article  Google Scholar 

Liu C, Liu Y, Zhao Y, Wei J, Ma Y, Liu Y et al (2020) Primary intracranial mesenchymal tumor with EWSR1–CREM gene fusion: a case report and literature review. World Neurosurg 142:318–324

Article  Google Scholar 

Poyuran R, Shah SP, Kesavapisharady K, Chandrasekharan K, Narasimhaiah D (2022) Intracranial mesenchymal tumour with EWSR1 gene rearrangement: the first report of intracranial mesenchymal tumour with FET–CREB fusion from India. Pathology. https://doi.org/10.1016/j.pathol.2022.02.007

Article  PubMed  Google Scholar 

Sciot R, Jacobs S, Calenbergh FV, Demaerel P, Wozniak A, Debiec-Rychter M (2018) Primary myxoid mesenchymal tumour with intracranial location: report of a case with a EWSR1-ATF1 fusion. Histopathology 72:880–883

Article  Google Scholar 

Tan NJH, Pratiseyo PD, Wahjoepramono EJ, Kuick CH, Goh JY, Chang KTE et al (2021) Intracranial myxoid angiomatoid fibrous histiocytoma with “classic” histology and EWSR1:CREM fusion providing insight for reconciliation with intracranial myxoid mesenchymal tumors. Neuropathology 41:306–314

CAS  Article  Google Scholar 

Valente Aguiar P, Pinheiro J, Lima J, Vaz R, Linhares P (2020) Myxoid mesenchymal intraventricular brain tumour with EWSR1–CREB1 gene fusion in an adult woman. Virchows Arch. https://doi.org/10.1007/s00428-020-02885-7

Article  PubMed  Google Scholar 

Velz J, Agaimy A, Frontzek K, Neidert MC, Bozinov O, Wagner U et al (2018) Molecular and clinicopathologic heterogeneity of intracranial tumors mimicking extraskeletal myxoid chondrosarcoma. J Neuropathol Exp Neurol 77:727–735

Article  Google Scholar 

Vizcaino MA, Giannini C, Chang HT, Kipp BR, Fritchie K, Vaubel R (2021) Intracranial angiomatoid fibrous histiocytoma with rhabdoid features: a mimic of rhabdoid meningioma. Brain Tumor Pathol 38:138–144

CAS  Article  Google Scholar 

Ward B, Wang CP, Macaulay RJB, Liu JKC (2020) Adult intracranial myxoid mesenchymal tumor with EWSR1-ATF1 gene fusion. World Neurosurg 143:91–96

Article  Google Scholar 

White MD, McDowell MM, Pearce TM, Bukowinski AJ, Greene S (2019) Intracranial myxoid mesenchymal tumor with rare EWSR1–CREM translocation. Pediatr Neurosurg 54:347–353

Article  Google Scholar 

Lemnos L, Salle H, Caire F, Duchesne M (2022) Angiomatoid fibrous histiocytoma: an atypical brain location newly described as intracranial mesenchymal tumor FET–CREB fusion-positive. Acta Neurol Belg. https://doi.org/10.1007/s13760-022-01966-5

Article  PubMed  Google Scholar 

Levy AS, Sakellakis A, Luther E, Morell AA, Rosenberg A, Saad AG et al (2022) Concurrent intraventricular intracranial myxoid mesenchymal tumor and ependymoma in a long-term Ewing sarcoma survivor. Neuropathology. https://doi.org/10.1111/neup.12844

Article  PubMed  Google Scholar 

Sasaki M, Hirono S, Gao Y, Suda I, Matsutani T, Ota M et al (2022) Clinicopathological and genomic features of pediatric intracranial myxoid mesenchymal tumor with both of EWSR1–CREM gene fusion and MAP3K13 mutation: a case report and comparison with adult cases in the literature. NMC Case Rep J 9:101–109

Article  Google Scholar 

Dunham C, Hussong J, Seiff M, Pfeifer J, Perry A (2008) Primary intracerebral angiomatoid fibrous histiocytoma: report of a case with a t(12;22)(q13;q12) causing type 1 fusion of the EWS and ATF-1 genes. Am J Surg Pathol 32:478–484

Article  Google Scholar 

留言 (0)

沒有登入
gif