Combined alteration of lamin and nuclear morphology influences the localization of the tumor-associated factor AKTIP

Burla R, Carcuro M, Raffa GD, Galati A, Raimondo D, Rizzo A, et al. AKTIP/Ft1, a new shelterin-interacting factor required for telomere maintenance. PLoS Genet. 2015;11(6):e1005167.

PubMed  PubMed Central  Article  CAS  Google Scholar 

La Torre M, Merigliano C, Burla R, Mottini C, Zanetti G, Del Giudice S, et al. Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits. Aging Cell. 2018;17(4):e12730.

Morita E, Sandrin V, Chung HY, Morham SG, Gygi SP, Rodesch CK, et al. Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis. EMBO J. 2007;26(19):4215–27.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Merigliano C, Burla R, La Torre M, Del Giudice S, Teo H, Liew CW, et al. AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody. PLoS Genet. 2021;17(8):e1009757.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Stoten CL, Carlton JG. ESCRT-dependent control of membrane remodelling during cell division. Semin Cell Dev Biol. 2018;74:50–65.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Burla R, Carcuro M, Torre ML, Fratini F, Crescenzi M, D'Apice MR, et al. The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence. Open Biol. 2016;6(8).

Stewart CL, Roux KJ, Burke B. Blurring the boundary: the nuclear envelope extends its reach. Science. 2007;318(5855):1408–12.

CAS  PubMed  Article  Google Scholar 

Schirmer EC, Florens L, Guan T, Yates JR 3rd, Gerace L. Nuclear membrane proteins with potential disease links found by subtractive proteomics. Science. 2003;301(5638):1380–2.

CAS  PubMed  Article  Google Scholar 

Kittisopikul M, Virtanen L, Taimen P, Goldman RD. Quantitative analysis of nuclear lamins imaged by super-resolution light microscopy. Cells. 2019;8(4).

Turgay Y, Eibauer M, Goldman AE, Shimi T, Khayat M, Ben-Harush K, et al. The molecular architecture of lamins in somatic cells. Nature. 2017;543(7644):261–4.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Butin-Israeli V, Adam SA, Goldman AE, Goldman RD. Nuclear lamin functions and disease. Trends Genet. 2012;28(9):464–71.

CAS  PubMed  PubMed Central  Article  Google Scholar 

de Leeuw R, Gruenbaum Y, Medalia O. Nuclear lamins: thin filaments with major functions. Trends Cell Biol. 2018;28(1):34–45.

PubMed  Article  CAS  Google Scholar 

Nandakumar V, Kelbauskas L, Hernandez KF, Lintecum KM, Senechal P, Bussey KJ, et al. Isotropic 3D nuclear morphometry of normal, fibrocystic and malignant breast epithelial cells reveals new structural alterations. PLoS One. 2012;7(1):e29230.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Nyirenda N, Farkas DL, Ramanujan VK. Preclinical evaluation of nuclear morphometry and tissue topology for breast carcinoma detection and margin assessment. Breast Cancer Res Treat. 2011;126(2):345–54.

PubMed  Article  Google Scholar 

Dubik N, Mai S. Lamin A/C: function in normal and tumor cells. Cancers (Basel). 2020;12(12).

Denais CM, Gilbert RM, Isermann P, McGregor AL, te Lindert M, Weigelin B, et al. Nuclear envelope rupture and repair during cancer cell migration. Science. 2016;352(6283):353–8.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Matsumoto A, Hieda M, Yokoyama Y, Nishioka Y, Yoshidome K, Tsujimoto M, et al. Global loss of a nuclear lamina component, lamin A/C, and LINC complex components SUN1, SUN2, and nesprin-2 in breast cancer. Cancer Med. 2015;4(10):1547–57.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Wazir U, Ahmed MH, Bridger JM, Harvey A, Jiang WG, Sharma AK, et al. The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer. Cell Mol Biol Lett. 2013;18(4):595–611.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Gong G, Chen P, Li L, Tan H, Zhou J, Zhou Y, et al. Loss of lamin A but not lamin C expression in epithelial ovarian cancer cells is associated with metastasis and poor prognosis. Pathol Res Pract. 2015;211(2):175–82.

CAS  PubMed  Article  Google Scholar 

Maresca G, Natoli M, Nardella M, Arisi I, Trisciuoglio D, Desideri M, et al. LMNA knock-down affects differentiation and progression of human neuroblastoma cells. PLoS ONE. 2012;7(9):e45513.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Willis ND, Cox TR, Rahman-Casans SF, Smits K, Przyborski SA, van den Brandt P, et al. Lamin A/C is a risk biomarker in colorectal cancer. PLoS ONE. 2008;3(8):e2988.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Kong L, Schafer G, Bu H, Zhang Y, Zhang Y, Klocker H. Lamin A/C protein is overexpressed in tissue-invading prostate cancer and promotes prostate cancer cell growth, migration and invasion through the PI3K/AKT/PTEN pathway. Carcinogenesis. 2012;33(4):751–9.

CAS  PubMed  Article  Google Scholar 

Bonne G, Quijano-Roy S. Emery-Dreifuss muscular dystrophy, laminopathies, and other nuclear envelopathies. Handb Clin Neurol. 2013;113:1367–76.

PubMed  Article  Google Scholar 

Gonzalo S, Kreienkamp R, Askjaer P. Hutchinson-Gilford Progeria Syndrome: a premature aging disease caused by LMNA gene mutations. Ageing Res Rev. 2017;33:18–29.

CAS  PubMed  Article  Google Scholar 

Earle AJ, Kirby TJ, Fedorchak GR, Isermann P, Patel J, Iruvanti S, et al. Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells. Nat Mater. 2020;19(4):464–73.

CAS  PubMed  Article  Google Scholar 

Cho S, Vashisth M, Abbas A, Majkut S, Vogel K, Xia Y, et al. Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell-cycle arrest. Dev Cell. 2019;49(6):920-35 e5.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Hah J, Kim DH. Deciphering nuclear mechanobiology in laminopathy. Cells. 2019;8(3).

Burla R, La Torre M, Maccaroni K, Verni F, Giunta S, Saggio I. Interplay of the nuclear envelope with chromatin in physiology and pathology. Nucleus. 2020;11(1):205–18.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Camozzi D, Capanni C, Cenni V, Mattioli E, Columbaro M, Squarzoni S, et al. Diverse lamin-dependent mechanisms interact to control chromatin dynamics. Focus on laminopathies Nucleus. 2014;5(5):427–40.

PubMed  Google Scholar 

Piersanti S, Sacchetti B, Funari A, Di Cesare S, Bonci D, Cherubini G, et al. Lentiviral transduction of human postnatal skeletal (stromal, mesenchymal) stem cells: in vivo transplantation and gene silencing. Calcif Tissue Int. 2006;78(6):372–84.

CAS  PubMed  Article  Google Scholar 

Pegoraro G, Kubben N, Wickert U, Gohler H, Hoffmann K, Misteli T. Ageing-related chromatin defects through loss of the NURD complex. Nat Cell Biol. 2009;11(10):1261–7.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Capanni C, Cenni V, Haraguchi T, Squarzoni S, Schuchner S, Ogris E, et al. Lamin A precursor induces barrier-to-autointegration factor nuclear localization. Cell Cycle. 2010;9(13):2600–10.

CAS  PubMed  Article  Google Scholar 

Remoli C, Michienzi S, Sacchetti B, Consiglio AD, Cersosimo S, Spica E, et al. Osteoblast-specific expression of the fibrous dysplasia (FD)-causing mutation Gsalpha(R201C) produces a high bone mass phenotype but does not reproduce FD in the mouse. J Bone Miner Res. 2015;30(6):1030–43.

CAS  PubMed  Article  Google Scholar 

Burla R, La Torre M, Zanetti G, Bastianelli A, Merigliano C, Del Giudice S, et al. p53-sensitive epileptic behavior and inflammation in Ft1 hypomorphic mice. Front Genet. 2018;9:581.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Piersanti S, Burla R, Licursi V, Brito C, La Torre M, Alves PM, et al. Transcriptional response of human neurospheres to helper-dependent CAV-2 vectors involves the modulation of DNA damage response, microtubule and centromere gene groups. PLoS ONE. 2015;10(7):e0133607.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Takai H, Smogorzewska A, de Lange T. DNA damage foci at dysfunctional telomeres. Curr Biol. 2003;13(17):6533–41.

Article  CAS  Google Scholar 

Xie W, Chojnowski A, Boudier T, Lim JS, Ahmed S, Ser Z, et al. A-type lamins form distinct filamentous networks with differential nuclear pore complex associations. Curr Biol. 2016;26(19):2651–8.

CAS  PubMed  Article  Google Scholar 

Schermelleh L, Carlton PM, Haase S, Shao L, Winoto L, Kner P, et al. Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy. Science. 2008;320(5881):1332–6.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Horn HF, Kim DI, Wright GD, Wong ES, Stewart CL, Burke B, et al. A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton. J Cell Biol. 2013;202(7):1023–39.

CAS  PubMed  PubMed Central  Article 

留言 (0)

沒有登入
gif