Gioffredi A, Maritati F, Oliva E, Buzio C. Eosinophilic granulomatosis with polyangiitis: an overview. Front Immuno Published Online. 2014;5:549. https://doi.org/10.3389/fimmu.2014.00549.
Fagni F, Bello F, Emmi G. Eosinophilic granulomatosis: dissecting the pathophysiology. Front Med. 2021. https://doi.org/10.3389/fmed.2021.627776.
• Lyons PA, Peters JE, Alberici F, Liley J, Coulson RMR, et al. Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status. Nat Commun. 2019;10(1):5120. https://doi.org/10.1038/s41467-019-12515-9. COMMENT: Study showing genetic differences in ANCA-positive and ANCA-negative eGPA.
Klion AD. How I treat hypereosinophilic syndromes. Blood. 2015;126(9):1069–77. https://doi.org/10.1182/blood-2014-11-551614.
CAS Article PubMed PubMed Central Google Scholar
Vaglio A, Buzio C, Zwerina J. Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): state of the art. Allergy. 2013;68:261–73. https://doi.org/10.1111/all.12088.
CAS Article PubMed Google Scholar
•• Wechsler ME, Akuthota P, Jayne D, Khoury P, Kilon CA, et al. Mepolizumab or placebo for eosinophilic granulomatosis with polyangiitis. N Engl J Med. 2017;376(20):1921–1932. COMMENT: Study that led to FDA approval for mepolizumab use in eGPA.
Wenzel S, Ford L, Pearlman D, Spector S, Sher L, Skobieranda F, et al. Dupilumab in persistent asthma with elevated eosinophil levels. N Engl J Med. 2013;368:2455–66. https://doi.org/10.1056/nejmoa1304048.
CAS Article PubMed Google Scholar
Eger K, Pet L, Weersink EJ, Bel EH. Complications of switching from anti-IL-5 or anti-IL-5R to dupilumab in corticosteroid-dependent severe asthma. J Allergy Clin Immunol Pract. 2021;9(7):2913–5. https://doi.org/10.1016/j.jaip.2021.02.042.
CAS Article PubMed Google Scholar
Castro M, Corren J, Pavord ID, et al. Dupilumab efficacy and safety in moderate-to-severe uncontrolled asthma. N Engl J Med. 2018;378(26):2486–96.
Isozaki T, Homma T, Sagara H, Kasama T. Role of cytokines in eGPA and the possibility of treatment with an anti-IL-5 antibody. J Clin Med. 2020;9:3890. https://doi.org/10.3390/jcm9123890.
CAS Article PubMed Central Google Scholar
Nagase H, Ueki S, Fujieda S. The roles of IL-5 and anti-IL-5 treatment in eosinophilic diseases: asthma, eosinophilic granulomatosis with polyangiitis, and eosinophilic chronic rhinosinusitis. Allergol Int. 2020;69:178–86. https://doi.org/10.1016/j.alit.2020.02.002.
CAS Article PubMed Google Scholar
Radonjic-Hoseli S, Valent P, Kilon AD, Wechsler ME, Simon H. Novel targeted therapies for eosinophilic-associated diseases and allergy. Annu Rev Pharmacol Toxicol. 2015;55:633–56. https://doi.org/10.1146/annurev-pharmtox-010814-124407.
Faverio P, Bonaiti G, Bini F, Vaghi A, Pesci A. Mepolizumab as the first targeted treatment for eosinophilic granulomatosis with polyangiitis: a review of current evidence and potential place in therapy. Ther Clin Risk Manag. 2018;14:2385–96. https://doi.org/10.2147/tcrm.s159949.
CAS Article PubMed PubMed Central Google Scholar
Guntur VP, Manka LA, Denson JL, Dunn RM, Dollin YT, Gill M, Kolakowski C, Strand MJ, Wechsler ME. Benralizumab as a steroid-sparing treatment option in eosinophilic granulomatosis with polyangiitis. J Allergy Clin Immunol Pract. 2021;9(3):1186-1193.e1. https://doi.org/10.1016/j.medcli.2021.07.017.
CAS Article PubMed Google Scholar
Chung SA, Langford CA, Maz M, Abril A, Gorelik M, Guyatt G, et al. American college of rheumatology/vasculitis foundation guideline for the management of antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheumatol. 2021;1–18. https://doi.org/10.1002/art.41773.
Junttila IS. Tuning the cytokine responses: an update on interleukin (IL)-4 and IL-13 receptor complexes. Front Immunol. 2018. https://doi.org/10.3389/fimmu.2018.00888.
Article PubMed PubMed Central Google Scholar
Xiaojing M. (ed). Regulation of cytokine gene expression in immunity and diseases. In: Advances in experimental medicine and biology. 1st ed. Springer Dordrecht; 2016; p. 941. ISBN: 978–94–024–0919–2. https://doi.org/10.1007/978-94-024-0921-5
Toru H, Ra C, Nonoyama S, Suzuki K, Yata J, Nakahata T. Induction of the high-affinity IgE receptor (FceRI) on human mast cells by IL-4. Int Immunol. 1996;8(9):1367–73. https://doi.org/10.1093/intimm/8.9.1367.
CAS Article PubMed Google Scholar
May RD, Fung M. Strategies targeting the IL-4/IL-13 axes in disease. Cytokine. 2015;75(1):89–116. https://doi.org/10.1016/j.cyto.2015.05.018.
CAS Article PubMed Google Scholar
Walter DM, McIntire JJ, Berry G, McKenzie ANJ, Donaldson DD, et al. Critical role for IL-13 in the development of allergen-induced airway hyperreactivity. J Immunol. 2001;167(8):4668–75. https://doi.org/10.4049/jimmunol.167.8.4668.
CAS Article PubMed Google Scholar
Highlights of prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/761055s020lbl.pdf. Accessed 10 July 2021.
Hogan SP, Mould A, Kikutani H, Ramsay AJ, Foster PS. Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J Clin Invest. 1997;99(6):1329–39. https://doi.org/10.1172/jci119292.
CAS Article PubMed PubMed Central Google Scholar
Webb DC, McKenzie AN, Koskinen AM, Yang M, Mattes J, Foster PS. Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity. J Immunol. 2000;165(1):108–13. https://doi.org/10.4049/jimmunol.165.1.108.
CAS Article PubMed Google Scholar
Kariyawasam HH, James LK, Gane SB. Dupilumab: clinical efficacy of blocking IL-4/IL-13 signalling in chronic rhinosinusitis with nasal polyps. Drug Des Devel Ther. 2020;14:1757–69. https://doi.org/10.2147/DDDT.S243053.
CAS Article PubMed PubMed Central Google Scholar
Bachert C, Han JK, Desrosiers M, Hellings PW, Amin N, Lee SE, Mullol J, Greos LS, Bosso JV, Laidlaw TM, Cervin AU, Maspero JF, Hopkins C, Olze H, Canonica GW, Paggiaro P, Cho SH, Fokkens WJ, Fujieda S, Zhang M, Lu X, Fan C, Draikiwicz S, Kamat SA, Khan A, Pirozzi G, Patel N, Graham NMH, Ruddy M, Staudinger H, Weinreich D, Stahl N, Yancopoulos GD, Mannent LP. Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. Lancet. 2019;394(10209):1638–50. https://doi.org/10.1016/s0140-6736(19)31881-1.
CAS Article PubMed Google Scholar
Menzella F, Montanari G, Patricelli G, Cavazza A, Galeone C, Ruggiero P, Bagnasco D, Facciolongo N. A case of chronic eosinophilic pneumonia in a patient treated with dupilumab. Ther Clin Risk Manag. 2019;15:869–75. https://doi.org/10.2147/tcrm.s207402.
Article PubMed PubMed Central Google Scholar
Furuta S, Iwamoto T, Nakajima H. Update on eosinophilic granulomatosis with polyangiitis. Allergol Int. 2019;68(4):430–6. https://doi.org/10.1016/j.alit.2019.06.004.
CAS Article PubMed Google Scholar
Moon BG, Takaki S, Miyake K, Takatsu K. The role of IL-5 for mature B-1 cells in homeostatic proliferation, cell survival, and Ig production. J Immunol. 2004;172(10):6020–9. https://doi.org/10.4049/jimmunol.172.10.6020.
CAS Article PubMed Google Scholar
Roufosse F. Targeting the interleukin-5 pathway for treatment of eosinophilic conditions other than asthma. Front Med (Lausanne). 2018;5:49. https://doi.org/10.3389/fmed.2018.00049.
Hajoui O, Janani R, Tulic M, Joubert P, Ronis T, et al. Synthesis of IL-13 by human B lymphocytes: regulation and role in IgE production. J Allergy Clin Immunol. 2004;114(3):657–63. https://doi.org/10.1016/j.jaci.2004.05.034.
CAS Article PubMed Google Scholar
McLeod JJ, Baker B, Ryan JJ. Mast cell production and response to IL-4 and IL-13. Cytokine. 2015;75(1):57–61. https://doi.org/10.1016/j.cyto.2015.05.019.
CAS Article PubMed PubMed Central Google Scholar
Angkasekwinai P, Sodthawon W, Jeerawattanawart S, Hansakon A, Pattanapanyasat K, et al. ILC2s activated by IL-25 promote antigen-specific Th2 and Th9 functions that contribute to the control of Trichinella spiralis infection. PLoS ONE. 2017;12(9): e0184684. https://doi.org/10.1371/journal.pone.0184684.
CAS Article PubMed PubMed Central Google Scholar
Liu D, Cao T, Wang N, Liu C, Ma N, et al. IL-25 attenuates rheumatoid arthritis through suppression of Th17 immune responses in an IL-13-dependent manner. Sci Rep. 2016;6:36002. https://doi.org/10.1038/srep36002.
CAS Article PubMed PubMed Central Google Scholar
Liu Y, Shao Z, Shangguan G, Bie Q, Zhang B. Biological properties and the role of IL-25 in disease pathogenesis. J Immunol Res. 2018;2018:6519465. https://doi.org/10.1155/2018/6519465.
CAS Article PubMed PubMed Central Google Scholar
Valizadeh A, Khosravi A, Zadeh LJ, Parizad EG. Role of IL-25 in immunity. J Clin Diagn Res. 2015;9(4):OE01-OE4. https://doi.org/10.7860/jcdr/2015/12235.5814.
Article PubMed PubMed Central Google Scholar
Doran E, Cai F, Holweg CTJ, Wong K, Brumm J, et al. Interleukin-13 in asthma and other eosinophilic disorders. Front Med (Lausanne). 2017;4:139. https://doi.org/10.3389/fmed.2017.00139.
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