Association Between the Intracellular Tacrolimus Concentration in CD3+ T Lymphocytes and CD14+ Monocytes and Acute Kidney Transplant Rejection

*Department of Internal Medicine, Division of Nephrology and Transplantation, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands;

†Erasmus MC Transplant Institute, Rotterdam, the Netherlands;

‡Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand;

§Department of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; and

¶Department of Pathology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.

Correspondence: Suwasin Udomkarnjananun, MD, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, the Netherlands (e-mail: [email protected]).

S. Udomkarnjananun received a grant from the King Chulalongkorn Memorial Hospital and Thai Red Cross Society for conducting research at the Erasmus MC.

D. A. Hesselink has received a grant support (paid to the Erasmus MC) from Astellas Pharma and Chiesi Pharma as well as consulting fees from Astellas Pharma, Chiesi Pharma, Medincell, Novartis Pharma, and Sangamo Therapeutics. M. C. Clahsen-Van Groningen received project funding (paid to Erasmus MC) from Astellas Pharma. The other authors have no conflicts of interest to declare.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.drug-monitoring.com).

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