Anisimov, V.N., Molekulyarnye i fiziologicheskie mekhanizmy stareniya (v 2-kh t.) (Molecular and Physiological Mechanisms of Aging (2 vols.)), St. Petersburg: Nauka, 2008.
Clinical Trials Database: Trial no. NCT03430037 of February 6, 2018, topic: “Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women (AFFIRM)” (April 14, 2021) [electronic resource], ClinicalTrials.gov. URL: https://clinicaltrials.gov/ct2/home.
www.who.int/selection_medicines/list/ru.
Gavrilov, I.V., Meshchaninov, V.N., Shcherbakov, D.L., et al., Screening of functional, biochemical and cell-hematological parameters of the body as markers of human aging, Vestn. Ural’skoi Med. Akad. Nauki, 2018, vol. 15, no. 5, pp. 691–703.
Gavrilov, I.V., Meshchaninov, V.N., Shcherbakov, D.L., et al., Aging of the body and age-related dynamics of biomarkers of human gerodiagnostics, Vestn. Ural’skoi Med. Akad. Nauki, 2020, vol. 17, no. 4, pp. 272–284.
Gavrilov, L.A. and Gavrilova, N.S., Is aging a disease? Viewpoint of biodemographers, Usp. Gerontol., 2017, vol. 30, no. 6, pp. 841–842.
Golubev, A.G., Is aging a disease? Viewpoint of a biogerontologist: Old age ≠ illness, Adv. Gerontol., 2017, vol. 30, no. 6, pp. 845–847.
Dil’man, V.M., Bol’shie biologicheskie chasy. Vvedenie v integral’nuyu meditsinu (Big Biological Clock. Introduction into Integral Medicine), Moscow: Znanie, 1986.
Trial “SRK-015 for Spinal Muscular Atrophy (SMA).” Scholar Rock Biopharmaceutical Company (April 15, 2021) [electronic resource], URL: https://scholarrock.com.
www.sens.org/mitosens.
Kovtun, O.P. and Tsyv’yan, P.B., Epigenetic mechanisms of fetal programming of diseases in children and adults, Ros. Vestn. Perinatol. Pediatr., 2009, vol. 54, no. 2, pp. 72–76.
http://www.proclarabio.com.
www.turn.bio.
Meshchaninov, V.N., Tkachenko, E.L., Zharkov, S.V., et al., Effects of synthetic peptides on aging tempos in patients with chronic polimorbid and psychoorganic disorders of the central nervous system at the stage of remission, Usp. Gerontol., 2015, vol. 28, no. 1, pp. 62–67.
Meshchaninov, V.N., Shcherbakov, D.L., and Lukash, V.A., Metabolizm kletochnykh struktur pri starenii i stresse (Metabolism of Cellular Structures in Aging and Stress), Yekaterinburg, 2017.
Moskalev, A.A., Is aging a disease? Viewpoint of a geneticist, Usp. Gerontol., 2017, vol. 30, no. 6, pp. 843–844.
Myakotnykh, V.S., Is aging a disease? Viewpoint of a geriatrist, Usp. Gerontol., 2017, vol. 30, no. 6, pp. 848–850.
Myakotnykh, V.S., Torgashov, M.N., Egorin, K.V., et al., Comparative analysis of different methods of geroprotection, Usp. Gerontol., 2016, vol. 29, no. 4, pp. 594–601.
www.cnio.es/investigacion-e-innovacion/programas-cientificos/programa-de-oncologia-molecular/grupo-de-telomeros-y-telomerasa.
Novikova, D.S., Garabadzhiu, A.V., Melino, G., et al., AMPK: structure, function and involvement in pathological processes, Biokhimiya, 2015, vol. 80, no. 2, pp. 163–183.
Novoselov, V.M., Is aging a disease? Usp. Gerontol., 2017, vol. 30, no. 6, pp. 836–840.
Rubinskii, A.V., Lin’kova, N.S., Chalisova, N.I., et al., Epigenetic regulation in pathology and aging, Usp. Gerontol., 2021, vol. 34, no. 1, pp. 10–17.
Khavinson, V.Kh., Therapeutic peptides: past, present, future, Klin. Med., 2020, vol. 98, no. 3, pp. 165–177.
Aguilera, A. and García-Muse, T., Causes of genome instability, Annu. Rev. Genet., 2013, vol. 4, pp. 1–32.
Aiken, C.E. and Ozanne, S.E., Transgenerational developmental programming, Hum. Reprod. Update, 2014, vol. 20, no. 1, pp. 63–75.
Armanios, M. and Blackburn, E.H., The telomere syndromes, Nat. Rev. Genet., 2012, vol. 13, no. 10, pp. 693–704.
CAS PubMed PubMed Central Article Google Scholar
Assadiasl, S., Mooney, N., Mohebbi, B., et al., Sirtuin 1: a dilemma in transplantation, J. Transplantat., 2020, vol. 2020, pp. 1–11. https://doi.org/10.1155/2020/9012980
Assefa, B.T., Tafere, G.G., Wondafrash, D.Z., and Gidey, M.T., The bewildering effect of AMPK activators in Alzheimer’s disease: Review of the current evidence, Biomed. Res. Int., 2020, vol. 2020, аrticle ID 9895121. https://doi.org/10.1155/2020/9895121
Barker, D.J. and Osmond, C., Childhood respiratory infection and adult chronic bronchitis in England and Wales, Brit. Med. J. (Clin. Res. Ed.), 1986, vol. 293, pp. 1271–1275.
Barzilai, N., Crandall, J.P., Kritchevsky, S.B., and Espeland, M.A., Metformin as a tool to target aging, Cell Metab., 2016, vol. 23, no. 6, pp. 1060–1065.
CAS PubMed PubMed Central Article Google Scholar
Blagosklonny, M.V., Aging is not programmed: genetic pseudo-program is a shadow of developmental growth, Cell Cycle, 2013, vol. 24, no. 12, pp. 3736–3742.
Blasco, M.A., Bobadilla, M., Flores, J.M., et al., Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres, eLife, 2018, vol. 7. e31299. https://doi.org/10.7554/eLife.31299
Bogan, K.L. and Brenner, C., Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition, Ann. Rev. Nutr., 2008, vol. 28, pp. 115–130.
Bosch-Presegué, L. and Vaquero, A., The dual role of sirtuins in cancer, Genes. Cancer, 2011, no. 6, pp. 648–662.
Carafa, V., Nebbioso, A., and Altucci, L., Sirtuins and disease: the road ahead, Front. Pharmacol., 2012, no. 3, pp. 4–10.
Carafa, V., Rotili, D., Forgione, M., et al., Sirtuin functions and modulation: from chemistry to the clinic, Clin. Epigenet., 2016, vol. 61, no. 8, pp. 2–21.
Chahal, J., Gómez-Aristizábal, A., Shestopaloff, K., et al., Bone marrow mesenchymal stromal cells in patients with osteoarthritis results in overall improvement in pain and symptoms and reduces synovial inflammation, Stem. Cells Transl. Med., 2019, vol. 8, no. 8, pp. 746–757.
CAS PubMed PubMed Central Article Google Scholar
Chen, Y., Hong, T., Wang, S., et al., Epigenetic modification of nucleic acids: from basic studies to medical applications, Chem. Soc. Rev., 2017, vol. 46, no. 10, pp. 2844–2872.
CAS PubMed Article Google Scholar
Chen, Y., Zhang, J., Lin, Y., et al., Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS, EMBO Rep., 2011, vol. 12, no. 6, pp. 534–541.
CAS PubMed PubMed Central Article Google Scholar
Chesnokova, A.Y., Ekimova, I.V., and Pastukhov, Y.F., Parkinson’s disease and aging, Adv. Gerontol., 2018, vol. 31, no. 5, pp. 668–678.
Chiti, F. and Dobson, C.M., Protein misfolding, amyloid formation and human disease: a summary of progress over the last decade, Annu. Rev. Biochem., 2017, vol. 86, pp. 27–68.
CAS PubMed Article Google Scholar
Coppé, J.P., Desprez, P.Y., Krtolica, A., and Campisi, J., The senescence-associated secretory phenotype: the dark side of tumor suppression, Ann. Rev. Pathol., 2010, no. 5, pp. 99–118.
Corbett, N. and Alda, M., On telomeres long and short, J. Psychiatry Neurosci., 2015, vol. 40, no. 1, pp. 3–4.
PubMed PubMed Central Article Google Scholar
Corbi, G., Conti, V., Scapagnini, G., et al., Role of sirtuins, calorie restriction and physical activity in aging, Front. Biosci. (Elite Ed.), 2012, no. 4, pp. 768–778.
Currais, A., Farrokhi, C., Dargusch, R., et al., Fisetin reduces the impact of aging on behavior and physiology in the rapidly aging SAMP8 mouse, J. Geront. A. Biol. Sci. Med. Sci., 2018, vol. 73, no. 3, pp. 299–307.
Dubal, D.B., Yokoyama, J.S., Zhu, L., et al., Life extension factor Klotho enhances cognition, Cell Rep., 2014, vol. 7, no. 4, pp. 1065–1076.
CAS PubMed PubMed Central Article Google Scholar
Dubal, D.B., Zhu, L., Sanchez, P.E., et al., Life extension factor Klotho prevents mortality and enhances cognition in HAPP transgenic mice, J. Neurosci., 2015, vol. 35, no. 6, pp. 2358–2371.
CAS PubMed PubMed Central Article Google Scholar
Fisher, R.A., Krishnan, R., Tsubery, H., et al., A bacteriophage capsid protein provides a general amyloid interaction motif (GAIM) that binds and remodels misfolded protein assemblies, J. Mol. Biol., 2014, vol. 426, no. 13, pp. 2500–2519.
PubMed Article CAS Google Scholar
Fontana, L., Partridge, L., and Longo, V.D., Extending healthy life span from yeast to humans, Science, 2010, vol. 5976, pp. 321–326.
Franceschi, C., Garagnani, P., Vitale, G., et al., Inflammaging and ‘garb-aging,’ Trends Endocr. Metab., 2017, no. 3, pp. 199–212.
Francheachi, C., Garagnani, P., Morsiani, C., et al., The continuum of aging and age-related diseases: common mechanisms but different rates, Front. Med., 2018, no. 6, pp. 21–23.
Freund, A., Orjalo, A.V., Desprez, P.Y., and Campisi, J., Inflammatory networks during cellular senescence: causes and consequences, Trends Mol. Med., 2010, vol. 16, no. 5, pp. 238–246.
CAS PubMed PubMed Central Article Google Scholar
Fulop, T., Witkowski, J.M., Olivieri, F., and Larbi, A., The integration of inflammaging in age-related diseases, Seminars Immunol., 2018, vol. 40, pp. 17–35.
Gal, H., Porat, Z., and Krizhanovsky, V., A multiparametric assay to evaluate senescent cells, Methods Mol. Biol., 2019, vol. 1896, pp. 107–117. https://doi.org/10.1007/978-1-4939-8931-7_11
CAS PubMed Article Google Scholar
Giardini, M.A., Segatto, M., da Silva, M.S., et al., Telomere and telomerase biology, Prog. Mol. Biol. Transl. Sci., 2014, vol. 125, pp. 1–40.
CAS PubMed Article Google Scholar
Goldberg, J., Currais, A., Prior, M., et al., The mitochondrial ATP-synthase is a shared drug target for aging and dementia, Aging Cell, 2018, vol. 17, no. 2, pp. 1–13.
Golpanian, S., DiFede, D.L., Khan, A., et al., Allogeneic human mesenchymal stem cell infusions for aging frailty, J. Gerontol. Biol. Sci., 2017, vol. 72, no. 11, pp. 1505–1512.
González, A., Hall, M.N., Lin, S.C., and Hardie, D.G., AMPK and TOR: the Yin and Yang of cellular nutrient sensing and growth control, Cell Metab., 2020, vol. 31, no. 3, pp. 472–492.
PubMed Article CAS Google Scholar
Gonzalez-Rodriguez, P.J., Tong, W., Xue, Q., et al., Fetal hypoxia results in programming of aberrant angiotensin II receptor expression patterns and kidney development, Int. J. Med. Sci., 2013, vol. 10, no. 5, pp. 532–538.
留言 (0)