Next-Generation Cancer Magnetic Resonance Imaging With Tumor-Targeted Alkylphosphocholine Metal Analogs

From the ∗Department of Radiology

†Department of Neurological Surgery

‡Department of Pharmaceutical Sciences

§Department of Medical Physics

∥Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI

¶Department of Radiology, University of Washington, Seattle, WA

#Neuroscience and Brain Disease Center, Graduate Institute of Biomedical Sciences, China Medical University, Taiwan

∗∗Department of Neurosurgery, Dell Medical School, University of Texas at Austin, Austin, TX.

Received for publication February 1, 2022; and accepted for publication, after revision, April 12, 2022.

Conflicts of interest and sources of funding: R.R.Z. was partially supported by the University of Wisconsin MD/PhD program via a National Institutes of Health T32 GM008692 grant as well as Department of Radiology and Neurological Surgery pilot funding. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. J.P.W. is a cofounder, and A.N.P., J.J.G., and R.H. have served as consultants of Archeus Technologies, which holds the licensing rights to Gd-NM600. Some of the information contained in the manuscript was presented at the biannual Contrast Media Research meeting in 2015 and 2017. R.R.Z. is partially supported by the University of Wisconsin MD/PhD program via T32 GM008692. P.A.C. and J.S.K. were partly supported by the Roger Loff Memorial Fund for GBM Research.

Correspondence to: Jamey P. Weichert, PhD, Department of Radiology, Wisconsin Institutes for Medical Research, Room 7133, 1111 Highland Ave, Madison, WI 53705. E-mail: [email protected].

Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (www.investigativeradiology.com).

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