Effect of Contrast Agent Dose Reduction on Vascular Enhancement and Image Quality in Thoracoabdominal Dynamic 3-Dimensional Magnetic Resonance Angiography: A Systematic Intraindividual Analysis in Pigs

From the ∗Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn

†MR and CT Contrast Media Research, Bayer AG, Berlin

‡Amsterdam UMC, locatie VUmc, Radiology and Nuclear Medicine Department, De Boelelaan 1118, 1081HV Amsterdam, the Netherlands

§Center for Radiology, Neuroradiology, Sonography and Nuclear Medicine, Krankenhaus der Barmherzigen Brüder, Trier, Germany.

Received for publication January 30, 2022; and accepted for publication, after revision, March 19, 2022.

Conflicts of interest and sources of funding: The study was performed with support of Bayer AG, Berlin, Germany. The company provided the animals, professionals experienced in handling of the animals including anesthesia, and also the clinical MR scanners that were used in this study. The coauthors G.J. and H.P. are employees of Bayer AG, Berlin, Germany.

The coauthors of the manuscript who are employees of either Bayer AG, Berlin, Germany, or with financial, consultant, institutional, and other relationships that might lead to bias or a conflict of interest, had no control over the finalization of the manuscript.

The other authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

Correspondence to: Dariusch R. Hadizadeh, MD, Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany. E-mail: [email protected].

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