Placebo Effect in Randomized Trials of Major Depressive Disorder With Psychotic Features: A Systematic Review and Descriptive Meta-Analysis

From the 1Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto

2Centre for Addiction and Mental Health, Toronto, Canada

3Department of Psychiatry, Weill Cornell Medicine of Cornell University

4Westchester Division, New York Presbyterian Hospital, New York, NY

5Centre for Mental Health, University Health Network, Toronto, Ontario, Canada

6University of Massachusetts Chan Medical School and UMass Memorial Health Care, Worcester, MA

7Department of Psychiatry, University of Pittsburgh School of Medicine

8UPMC Western Psychiatric Hospital, Pittsburgh, PA.

Received November 24, 2021; accepted after revision June 9, 2022.

Reprints: Benoit H. Mulsant, MD, Department of Psychiatry, University of Toronto, 250 College St, Rm 835, Toronto, Ontario, Canada (e-mail: [email protected]).

Except for the first 2 authors and the senior corresponding author, all authors have contributed equally and are listed in alphabetical order.

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