Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.

Correspondence: Douglas G. Tilley, PhD, Room 945A MERB, Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, 3500 N. Broad St, Philadelphia, PA 19140 (e-mail: [email protected]).

Supported by National Institutes of Health grants R01 HL136219, HL139522 and P01 HL147841 (D.G.T.) and T32 HL091804 (H.X.).

The authors report no conflicts of interest.