Zafar A, Wang W, Liu G, Wang X, Xian W, McKeon F, Foster J, Zhou J, Zhang R (2021) Molecular targeting therapies for neuroblastoma: progress and challenges. Med Res Rev 41:961–1021

Article  Google Scholar 

Brodeur GM (2018) Spontaneous regression of neuroblastoma. Cell Tissue Res 372:277–286

CAS  Article  Google Scholar 

Louis CU, Shohet JM (2015) Neuroblastoma: molecular pathogenesis and therapy. Annu Rev Med 66:49–63

CAS  Article  Google Scholar 

Fjodorova M, Noakes Z, Li M (2020) A role for TGFbeta signalling in medium spiny neuron differentiation of human pluripotent stem cells. Neuronal Signal 4:20200004

Article  Google Scholar 

Lin YL, Lin YW, Nhieu J, Zhang X, Wei LN (2020) Sonic hedgehog-Gli1 signaling and cellular retinoic acid binding protein 1 gene regulation in motor neuron differentiation and diseases. Int J Mol Sci 21:4125

CAS  Article  Google Scholar 

De Gregorio R, Pulcrano S, De Sanctis C, Volpicelli F, Guatteo E, von Oerthel L, Latagliata EC, Esposito R, Piscitelli RM, Perrone-Capano C, Costa V, Greco D, Puglisi-Allegra S, Smidt MP, di Porzio U, Caiazzo M, Mercuri NB, Li M, Bellenchi GC (2018) miR-34b/c regulates Wnt1 and enhances mesencephalic dopaminergic neuron differentiation. Stem Cell Rep 10:1237–1250

Article  Google Scholar 

Ben-Shushan E, Feldman E, Reubinoff BE (2015) Notch signaling regulates motor neuron differentiation of human embryonic stem cells. Stem Cells 33:403–415

CAS  Article  Google Scholar 

Toresson H, Mata de Urquiza A, Fagerstrom C, Perlmann T, Campbell K (1999) Retinoids are produced by glia in the lateral ganglionic eminence and regulate striatal neuron differentiation. Development 126:1317–1326

CAS  Article  Google Scholar 

Carpentier A, Balitrand N, Rochette-Egly C, Shroot B, Degos L, Chomienne C (1997) Distinct sensitivity of neuroblastoma cells for retinoid receptor agonists: evidence for functional receptor heterodimers. Oncogene 15:1805–1813

CAS  Article  Google Scholar 

Zhang T, Gygi SP, Paulo JA (2021) Temporal proteomic profiling of SH-SY5Y differentiation with retinoic acid using FAIMS and real-time searching. J Proteome Res 20:704–714

CAS  Article  Google Scholar 

Delescluse C, Cavey MT, Martin B, Bernard BA, Reichert U, Maignan J, Darmon M, Shroot B (1991) Selective high affinity retinoic acid receptor alpha or beta-gamma ligands. Mol Pharmacol 40:556–562

CAS  PubMed  Google Scholar 

Gianni M, Li Calzi M, Terao M, Guiso G, Caccia S, Barbui T, Rambaldi A, Garattini E (1996) AM580, a stable benzoic derivative of retinoic acid, has powerful and selective cyto-differentiating effects on acute promyelocytic leukemia cells. Blood 87:1520–1531

CAS  Article  Google Scholar 

Gianni M, Ponzanelli I, Mologni L, Reichert U, Rambaldi A, Terao M, Garattini E (2000) Retinoid-dependent growth inhibition, differentiation and apoptosis in acute promyelocytic leukemia cells. Expression and activation of caspases. Cell Death Differ 7:447–460

CAS  Article  Google Scholar 

Brok-Volchanskaya VS, Bennin DA, Suknuntha K, Klemm LC, Huttenlocher A, Slukvin I (2019) Effective and rapid generation of functional neutrophils from induced pluripotent stem cells using ETV2-modified mRNA. Stem Cell Rep 13:1099–1110

CAS  Article  Google Scholar 

Araoka T, Mae S, Kurose Y, Uesugi M, Ohta A, Yamanaka S, Osafune K (2014) Efficient and rapid induction of human iPSCs/ESCs into nephrogenic intermediate mesoderm using small molecule-based differentiation methods. PLoS ONE 9:e84881

Article  Google Scholar 

Xie C, Mao X, Huang J, Ding Y, Wu J, Dong S, Kong L, Gao G, Li CY, Wei L (2011) KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases. Nucleic Acids Res 39:W316-322

CAS  Article  Google Scholar 

Harrirchian MH, Mohammadzadeh Honarvar N, Koohdani F, Bitarafan S, Siassi F, Jafarirad S, Abdolahi M, Salehi E, Saharian MA, Rouystaee H, Eshraghian MR, Saboor-Yarghi AA (2014) The effect of vitamin A supplementation on disease progression, cytokine levels and gene expression in multiple sclerotic patients: study protocol for a randomized controlled trial. Acta Med Iran 52:94–100

CAS  PubMed  Google Scholar 

Janesick A, Wu SC, Blumberg B (2015) Retinoic acid signaling and neuronal differentiation. Cell Mol Life Sci 72:1559–1576

CAS  Article  Google Scholar 

Jones-Villeneuve EM, Rudnicki MA, Harris JF, McBurney MW (1983) Retinoic acid-induced neural differentiation of embryonal carcinoma cells. Mol Cell Biol 3:2271–2279

CAS  PubMed  PubMed Central  Google Scholar 

Jones-Villeneuve EM, McBurney MW, Rogers KA, Kalnins VI (1982) Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J Cell Biol 94:253–262

CAS  Article  Google Scholar 

Hou PS, Huang WC, Chiang W, Lin WC, Chien CL (2014) Impaired neural differentiation potency by retinoic acid receptor-alpha pathway defect in induced pluripotent stem cells. Cell Reprogram 16:467–476

CAS  Article  Google Scholar 

Zhong LR, Chen X, Park E, Sudhof TC, Chen L (2018) Retinoic acid receptor RARalpha-dependent synaptic signaling mediates homeostatic synaptic plasticity at the inhibitory synapses of mouse visual cortex. J Neurosci 38:10454–10466

CAS  Article  Google Scholar 

Yuan A, Rao MV, Veeranna A, Nixon RA (2017) Neurofilaments and neurofilament proteins in health and disease. Cold Spring Harb Perspect Biol 9:018309

Article  Google Scholar 

Laser-Azogui A, Kornreich M, Malka-Gibor E, Beck R (2015) Neurofilament assembly and function during neuronal development. Curr Opin Cell Biol 32:92–101

CAS  Article  Google Scholar 

Kirkcaldie MTK, Dwyer ST (2017) The third wave: intermediate filaments in the maturing nervous system. Mol Cell Neurosci 84:68–76

CAS  Article  Google Scholar 

Lariviere RC, Julien JP (2004) Functions of intermediate filaments in neuronal development and disease. J Neurobiol 58:131–148

CAS  Article  Google Scholar 

Rao MV, Yuan A, Campbell J, Kumar A, Nixon RA (2012) The C-terminal domains of NF-H and NF-M subunits maintain axonal neurofilament content by blocking turnover of the stationary neurofilament network. PLoS ONE 7:e44320

CAS  Article  Google Scholar 

Larsen AP (2010) Role of ERG1 isoforms in modulation of ERG1 channel trafficking and function. Pflugers Arch 460:803–812

CAS  Article  Google Scholar 

Partemi S, Cestele S, Pezzella M, Campuzano O, Paravidino R, Pascali VL, Zara F, Tassinari CA, Striano S, Oliva A, Brugada R, Mantegazza M, Striano P (2013) Loss-of-function KCNH2 mutation in a family with long QT syndrome, epilepsy, and sudden death. Epilepsia 54:e112-116

CAS  Article  Google Scholar 

Cole BA, Clapcote SJ, Muench SP, Lippiat JD (2021) Targeting KNa1.1 channels in KCNT1-associated epilepsy. Trends Pharmacol Sci 42:700–713

CAS  Article  Google Scholar 

Milligan CJ, Li M, Gazina EV, Heron SE, Nair U, Trager C, Reid CA, Venkat A, Younkin DP, Dlugos DJ, Petrovski S, Goldstein DB, Dibbens LM, Scheffer IE, Berkovic SF, Petrou S (2014) KCNT1 gain of function in 2 epilepsy phenotypes is reversed by quinidine. Ann Neurol 75:581–590

CAS  Article  Google Scholar 

Bausch AE, Ehinger R, Straubinger J, Zerfass P, Nann Y, Lukowski R (2018) Loss of sodium-activated potassium channel slack and FMRP differentially affect social behavior in mice. Neuroscience 384:361–374

CAS  Article  Google Scholar 

Oikawa T, Okayasu I, Ashino H, Morita I, Murota S, Shudo K (1993) Three novel synthetic retinoids, Re 80, Am 580 and Am 80, all exhibit anti-angiogenic activity in vivo. Eur J Pharmacol 249:113–116

CAS  Article  Google Scholar 

Lu Y, Bertran S, Samuels TA, Mira-y-Lopez R, Farias EF (2010) Mechanism of inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARalpha agonist AM580. Oncogene 29:3665–3676

CAS  Article  Google Scholar 

Cheng YH, Utsunomiya H, Pavone ME, Yin P, Bulun SE (2011) Retinoic acid inhibits endometrial cancer cell growth via multiple genomic mechanisms. J Mol Endocrinol 46:139–153

CAS  Article  Google Scholar 

Goncalves MB, Clarke E, Hobbs C, Malmqvist T, Deacon R, Jack J, Corcoran JP (2013) Amyloid beta inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor alpha agonist. Eur J Neurosci 37:1182–1192

Article  Google Scholar