Irisin and Triglyceride Glucose Index as Markers of Dyslipidemia in Young Adults

Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012;11:481: 463–8.

Article  Google Scholar 

Hofmann T, Elbelt U, Stengel A. Irisin as a muscle-derived hormone stimulating thermogenesis–a critical update. Peptides. 2014;54:89–100.

CAS  Article  Google Scholar 

Sousa RAL, Improta-Caria AC, Souza BSF. Exercise-Linked Irisin: Consequences on Mental and Cardiovascular Health in Type 2 Diabetes. Int J Mol Sci. 2021;22(4):2199.

Article  Google Scholar 

Pardo M, Crujeiras AB, Amil M, Aguera Z, Jiménez-Murcia S, Baños R, et al. Association of irisin with fat mass, resting energy expenditure, and daily activity in conditions of extreme body mass index. Int J Endocrinol. 2014;7:857270.

Google Scholar 

Qiu S, Cai X, Yin H, Zügel M, Sun Z, Steinacker JM, Schumann U. Association between circulating irisin and insulin resistance in non-diabetic adults: A meta-analysis. Metabolism. 2016;65(6):825–34.

CAS  Article  Google Scholar 

Pekkala S, Wiklund PK, Hulmi JJ, Ahtiainen JP, Horttanainen M, Pöllänen E, et al. Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health? J Physiol. 2013;591(21):5393–400.

CAS  Article  Google Scholar 

Lee SH, Han K, Yang HK, Kim MK, Yoon KH, Kwon HS, Park YM. Identifying subgroups of obesity using the product of triglycerides and glucose: the Korea National Health and Nutrition Examination Survey. Clin Endocrinol. 2015;82(2):213–20.

CAS  Article  Google Scholar 

Crujeiras AB, Zulet MA, Lopez-Legarrea P, de la Iglesia R, Pardo M, Carreira MC, et al. Association between circulating irisin levels and the promotion of insulin resistance during the weight maintenance period after a dietary weight-lowering program in obese patients. Metabolism. 2014;63(4):520–31.

CAS  Article  Google Scholar 

Nagarathna R, Bali P, Anand A, Srivastava V, Patil S, Sharma G, et al. Prevalence of Diabetes and Its Determinants in the Young Adults Indian Population-Call for Yoga Intervention. Front Endocrinol (Lausanne). 2020;11:507064.

Article  Google Scholar 

Salazar J, Bermúdez V, Calvo M, Olivar LC, Luzardo E, Navarro C, et al. Optimal cutoff for the evaluation of insulin resistance through triglyceride-glucose index: A crosssectional study in a Venezuelan population. F1000Res. 2017;6:1337.

Article  Google Scholar 

Ding X, Wang X, Wu J, et al. Triglyceride–glucose index and the incidence of atherosclerotic cardiovascular diseases: a meta-analysis of cohort studies. Cardiovasc Diabetol. 2021;20:76.

CAS  Article  Google Scholar 

Stegenga H, Haines A, Jones K, Wilding J. Identification, assessment, and management of overweight and obesity: summary of updated NICE guidance BMJ 2014; 349:g6608.

Rana KS, Pararasa C, Afzal I, Nagel DA, Hill EJ, Bailey CJ, et al. Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels. Cardiovasc Diabetol. 2017;16(1):147.

Article  Google Scholar 

Er LK, Wu S, Chou HH, Hsu LA, Teng MS, Sun YC, Ko YL. Triglyceride Glucose Body Mass Index Is a Simple and Clinically Useful Surrogate Marker for Insulin Resistance in Nondiabetic Individuals. PLoS ONE. 2016;11(3):e0149731.

Article  Google Scholar 

Martinez Munoz IY, Camarillo Romero EDS, Garduno Garcia JJ. Irisin a Novel Metabolic Biomarker: Present Knowledge and Future Directions. Int J Endocrinol. 2018: 7816806.

Yavor Assyov A, Gateva V, Karamfilova T, Gatev I, Nedeva T, Velikova, et al. Impact of testosterone treatment on circulating irisin in men with late-onset hypogonadism and metabolic syndrome. The Aging Male. 2020;23(5):1381–7.

Article  Google Scholar 

Zhu D, Wang H, Zhang J, Zhang X, Xin C, Zhang F, et al. Irisin improves endothelial function in type 2 diabetes through reducing oxidative/nitrative stresses. J Mol Cell Cardiol. 2015;87:138–47.

CAS  Article  Google Scholar 

Ross R, Neeland IJ, Yamashita S, Shai I, Seidell J, Magni P, et al. Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity. Nat Rev Endocrinol. 2020;16(3):177–89.

Article  Google Scholar 

Leiva AM, Martínez MA, Cristi-Montero C, Salas C, Ramírez-Campillo R, Díaz Martínez X, et al. Sedentary lifestyle is associated with metabolic and cardiovascular risk factors independent of physical activity. Rev Med Chil. 2017;145(4):458–67.

Article  Google Scholar 

Oelmann S, Nauck M, Völzke H, Bahls M, Friedrich N. Circulating Irisin Concentrations Are Associated with a Favourable Lipid Profile in the General Population. PLoS ONE. 2016;11(4):e0154319.

Article  Google Scholar 

Zhang Y, Mu Q, Zhou Z, Song H, Zhang Y, Wu F, et al. Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Density Lipoprotein Induced Vascular Inflammation and Endothelial Dysfunction. PLoS One. 2016;11(6):e0158038.

Article  Google Scholar 

Lu J, Xiang G, Liu M, Mei W, Xiang L, Dong J. Irisin protects against endothelial injury and ameliorates atherosclerosis in apolipoprotein E-Null diabetic mice. Atherosclerosis. 2015;243(2):438–48.

CAS  Article  Google Scholar 

Zhang HJ, Zhang XF, Ma ZM, Pan LL, Chen Z, Han HW, et al. Irisin is inversely associated with intrahepatic triglyceride contents in obese adults. J Hepatol. 2013;59(3):557–62.

CAS  Article  Google Scholar 

Xu J, Lloyd DJ, Hale C, Stanislaus S, Chen M, Sivits G, et al. Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes. 2009;58(1):250–9.

CAS  Article  Google Scholar 

Badman MK, Pissios P, Kennedy AR, Koukos G, Flier JS, Maratos-Flier E. Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states. Cell Metab. 2007;5(6):426–37.

CAS  Article  Google Scholar 

Huh JY, Panagiotou G, Mougios V, Brinkoetter M, Vamvini MT, Schneider BE, Mantzoros CS. FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism. 2012;61(12):1725–38.

CAS  Article  Google Scholar 

Park KH, Zaichenko L, Brinkoetter M, Thakkar B, Sahin-Efe A, Joung KE, et al. Circulating irisin in relation to insulin resistance and the metabolic syndrome. J Clin Endocrinol Metab. 2013;98(12):4899–907.

CAS  Article  Google Scholar 

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