aUniv. Lille, CNRS, Inserm, CHU Lille, UMR 8576 – U1285 – UGSF – Unité de Glycobiologie Structurale et Fonctionnelle, Service de Médecine Intensive – Réanimation, France

bDepartment of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organization (MICRO), St. James's Hospital

cDepartment of Clinical medicine, School of Medicine, Trinity College Dublin, Dublin Ireland

dHospital Clinic, IDIBAPS, Universidad de Barcelona, Ciberes, Barcelona, Spain

Correspondence to Anahita Rouzé, MD, Critical Care Center, Lille University Hospital, Lille F-59000, France. Tel: +0033 320444084; e-mail: [email protected]