Reddihough DS, Marraffa C, Mouti A, O’Sullivan M, Lee KJ, Orsini F, Hazell P, Granich J, Whitehouse AJO, Wray J, Dossetor D, Santosh P, Silove N, Kohn M (2019) Effect of fluoxetine on obsessive-compulsive behaviors in children and adolescents with autism spectrum disorders: a randomized clinical trial. JAMA 322:1561–1569
CAS PubMed PubMed Central Article Google Scholar
Wong DT, Perry KW, Bymaster FP (2005) Case history: the discovery of fluoxetine hydrochloride (Prozac). Nat Rev Drug Discov 4:764–774
CAS PubMed Article Google Scholar
Shelton CI (2004) Long-term management of major depressive disorder: are differences among antidepressant treatments meaningful? J Clin Psychiatry 65(Suppl 17):29–33
Caiaffo V, Oliveira BD, de Sa FB, Evencio Neto J (2016) Anti-inflammatory, antiapoptotic, and antioxidant activity of fluoxetine. Pharmacol Res Perspect 4:e00231
PubMed PubMed Central Article CAS Google Scholar
Encinas JM, Vaahtokari A, Enikolopov G (2006) Fluoxetine targets early progenitor cells in the adult brain. Proc Natl Acad Sci USA 103:8233–8238
CAS PubMed PubMed Central Article Google Scholar
Meyer JH, Cervenka S, Kim MJ, Kreisl WC, Henter ID, Innis RB (2020) Neuroinflammation in psychiatric disorders: PET imaging and promising new targets. Lancet Psychiatry 7:1064–1074
PubMed PubMed Central Article Google Scholar
Mondelli V, Vernon AC, Turkheimer F, Dazzan P, Pariante CM (2017) Brain microglia in psychiatric disorders. Lancet Psychiatry 4:563–572
Liu D, Wang Z, Liu S, Wang F, Zhao S, Hao A (2011) Anti-inflammatory effects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cells. Neuropharmacology 61:592–599
CAS PubMed Article Google Scholar
Tian M, Yang M, Li Z, Wang Y, Chen W, Yang L, Li Y, Yuan H (2019) Fluoxetine suppresses inflammatory reaction in microglia under OGD/R challenge via modulation of NF-kappaB signaling. Biosci Rep 39:BSR20181584
CAS PubMed PubMed Central Article Google Scholar
Lanquillon S, Krieg JC, Bening-Abu-Shach U, Vedder H (2000) Cytokine production and treatment response in major depressive disorder. Neuropsychopharmacology 22:370–379
CAS PubMed Article Google Scholar
Alboni S, Poggini S, Garofalo S, Milior G, El Hajj H, Lecours C, Girard I, Gagnon S, Boisjoly-Villeneuve S, Brunello N, Wolfer DP, Limatola C, Tremblay ME, Maggi L, Branchi I (2016) Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment. Brain Behav Immun 58:261–271
CAS PubMed Article Google Scholar
Ha E, Jung KH, Choe BK, Bae JH, Shin DH, Yim SV, Baik HH (2006) Fluoxetine increases the nitric oxide production via nuclear factor kappa B-mediated pathway in BV2 murine microglial cells. Neurosci Lett 397:185–189
CAS PubMed Article Google Scholar
Kraemer HC, Frank E, Kupfer DJ (2006) Moderators of treatment outcomes: clinical, research, and policy importance. JAMA 296:1286–1289
CAS PubMed Article Google Scholar
Rahimian R, Wakid M, O’Leary LA, Mechawar N (2021) The emerging tale of microglia in psychiatric disorders. Neurosci Biobehav Rev 131:1–29
Galloway DA, Phillips AEM, Owen DRJ, Moore CS (2019) Phagocytosis in the brain: homeostasis and disease. Front Immunol 10:790
CAS PubMed PubMed Central Article Google Scholar
Knuesel I, Chicha L, Britschgi M, Schobel SA, Bodmer M, Hellings JA, Toovey S, Prinssen EP (2014) Maternal immune activation and abnormal brain development across CNS disorders. Nat Rev Neurol 10:643–660
CAS PubMed Article Google Scholar
Wohleb ES, Terwilliger R, Duman CH, Duman RS (2018) Stress-induced neuronal colony stimulating factor 1 provokes microglia-mediated neuronal remodeling and depressive-like behavior. Biol Psychiatry 83:38–49
CAS PubMed Article Google Scholar
Lehmann ML, Cooper HA, Maric D, Herkenham M (2016) Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophages. J Neuroinflamm 13:224
Schafer DP, Lehrman EK, Kautzman AG, Koyama R, Mardinly AR, Yamasaki R, Ransohoff RM, Greenberg ME, Barres BA, Stevens B (2012) Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron 74:691–705
CAS PubMed PubMed Central Article Google Scholar
Stevens B, Allen NJ, Vazquez LE, Howell GR, Christopherson KS, Nouri N, Micheva KD, Mehalow AK, Huberman AD, Stafford B, Sher A, Litke AM, Lambris JD, Smith SJ, John SW, Barres BA (2007) The classical complement cascade mediates CNS synapse elimination. Cell 131:1164–1178
CAS PubMed Article Google Scholar
Fonseca MI, Chu SH, Hernandez MX, Fang MJ, Modarresi L, Selvan P, MacGregor GR, Tenner AJ (2017) Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brain. J Neuroinflamm 14:48
Takayama F, Hayashi Y, Wu Z, Liu Y, Nakanishi H (2016) Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system. Sci Rep 6:30006
CAS PubMed PubMed Central Article Google Scholar
Fonken LK, Frank MG, Kitt MM, Barrientos RM, Watkins LR, Maier SF (2015) Microglia inflammatory responses are controlled by an intrinsic circadian clock. Brain Behav Immun 45:171–179
CAS PubMed Article Google Scholar
Mavroudis PD, DuBois DC, Almon RR, Jusko WJ (2018) Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat. PLoS ONE 13:e0197534
PubMed PubMed Central Article CAS Google Scholar
Wolff SEC, Wang XL, Jiao H, Sun J, Kalsbeek A, Yi CX, Gao Y (2020) The effect of Rev-erbalpha agonist SR9011 on the immune response and cell metabolism of microglia. Front Immunol 11:550145
CAS PubMed PubMed Central Article Google Scholar
Wang XL, Wolff SEC, Korpel N, Milanova I, Sandu C, Rensen PCN, Kooijman S, Cassel JC, Kalsbeek A, Boutillier AL, Yi CX (2020) Deficiency of the circadian clock gene Bmal1 reduces microglial immunometabolism. Front Immunol 11:586399
CAS PubMed PubMed Central Article Google Scholar
Salgado-Delgado R, Tapia Osorio A, Saderi N, Escobar C (2011) Disruption of circadian rhythms: a crucial factor in the etiology of depression. Depress Res Treat 2011:839743
PubMed PubMed Central Google Scholar
Wirz-Justice A, Cajochen C, Nussbaum P (1997) A schizophrenic patient with an arrhythmic circadian rest-activity cycle. Psychiatry Res 73:83–90
CAS PubMed Article Google Scholar
Chouinard S, Poulin J, Stip E, Godbout R (2004) Sleep in untreated patients with schizophrenia: a meta-analysis. Schizophr Bull 30:957–967
Afonso P, Brissos S, Figueira ML, Paiva T (2011) Schizophrenia patients with predominantly positive symptoms have more disturbed sleep-wake cycles measured by actigraphy. Psychiatry Res 189:62–66
Gold AK, Kinrys G (2019) Treating circadian rhythm disruption in bipolar disorder. Curr Psychiatry Rep 21:14
PubMed PubMed Central Article Google Scholar
Bersani G, Bersani FS, Prinzivalli E, Limpido L, Marconi D, Valeriani G, Colletti C, Anastasia A, Pacitti F (2012) Premorbid circadian profile of patients with major depression and panic disorder. Riv Psichiatr 47:407–412
Schubert JR, Coles ME (2013) Obsessive-compulsive symptoms and characteristics in individuals with delayed sleep phase disorder. J Nerv Ment Dis 201:877–884
You MJ, Bang M, Park HS, Yang B, Jang KB, Yoo J, Hwang DY, Kim M, Kim B, Lee SH, Kwon MS (2020) Human umbilical cord-derived mesenchymal stem cells alleviate schizophrenia-relevant behaviors in amphetamine-sensitized mice by inhibiting neuroinflammation. Transl Psychiatry 10:123
CAS PubMed PubMed Central Article Google Scholar
You MJ, Rim C, Kang YJ, Kwon MS (2021) A new method for obtaining bankable and expandable adult-like microglia in mice. J Neuroinflamm 18:294
Coogan AN, Piggins HD (2003) Circadian and photic regulation of phosphorylation of ERK1/2 and Elk-1 in the suprachiasmatic nuclei of the Syrian hamster. J Neurosci 23:3085–3093
CAS PubMed PubMed Central Article Google Scholar
Ginty DD, Kornhauser JM, Thompson MA, Bading H, Mayo KE, Takahashi JS, Greenberg ME (1993) Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science 260:238–241
CAS PubMed Article Google Scholar
Lee B, Li A, Hansen KF, Cao R, Yoon JH, Obrietan K (2010) CREB influences timing and entrainment of the SCN circadian clock. J Biol Rhythms 25:410–420
留言 (0)