aGastroenterology Department, Portuguese Oncology Institute of Porto

bMEDCIDS - Department of Community Medicine, Health Information and Decision, Faculty of Medicine, University of Porto

cDepartment of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto

dGastroenterology Department, Lisboa Ocidental Hospital Center, Egas Moniz Hospital

eGastroenterology Department, Lusíadas Hospital, Lisbon

fGastroenterology Department, Hospital of Braga, Braga

gGastroenterology Department, Porto University Hospital Center

hInstitute of Biomedical Sciences Abel Salazar, University of Porto, Porto

iGastroenterology Department, Vila Nova de Gaia Hospital Center, Vila Nova de Gaia

jGastroenterology Department, Senhora da Oliveira Hospital, Guimarães

kLife and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga

lICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães

mGastroenterology Department, Portuguese Oncology Institute of Coimbra, Coimbra

nGastroenterology Department, Trás-os-Montes e Alto Douro Hospital Center, Vila Real

oGastroenterology Department, Portuguese Oncology Institute of Lisbon, Lisbon, Portugal

Received 6 November 2021 Accepted 28 May 2022

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Correspondence to Marta Rodríguez-Carrasco, MD, Gastroenterology Department, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino de Almeida 865, 4200-072, Porto, Portugal, Tel: +351 225 084 000; e-mail: [email protected]