Upregulation of miR-499a-5p Decreases Cerebral Ischemia/Reperfusion Injury by Targeting PDCD4

Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116(2):281–297. https://doi.org/10.1016/s0092-8674(04)00045-5

CAS  Article  PubMed  Google Scholar 

Begum G, Yuan H, Kahle KT, Li L, Wang S, Shi Y, Shmukler BE, Yang SS, Lin SH, Alper SL, Sun D (2015) Inhibition of WNK3 kinase signaling reduces brain damage and accelerates neurological recovery after stroke. Stroke 46(7):1956–1965. https://doi.org/10.1161/STROKEAHA.115.008939

CAS  Article  PubMed  PubMed Central  Google Scholar 

Benjamin EJ, Virani SS, Callaway CW, Chamberlain AM, Chang AR, Cheng S, Chiuve SE, Cushman M, Delling FN, Deo R, de Ferranti SD, Ferguson JF, Fornage M, Gillespie C, Isasi CR, Jimenez MC, Jordan LC, Judd SE, Lackland D, Lichtman JH, Lisabeth L, Liu S, Longenecker CT, Lutsey PL, Mackey JS, Matchar DB, Matsushita K, Mussolino ME, Nasir K, O’Flaherty M, Palaniappan LP, Pandey A, Pandey DK, Reeves MJ, Ritchey MD, Rodriguez CJ, Roth GA, Rosamond WD, Sampson UKA, Satou GM, Shah SH, Spartano NL, Tirschwell DL, Tsao CW, Voeks JH, Willey JZ, Wilkins JT, Wu JH, Alger HM, Wong SS, Muntner P, American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee (2018) Heart Disease and Stroke Statistics—2018 update: a report from the American Heart Association. Circulation 137(12):e67–e492. https://doi.org/10.1161/CIR.0000000000000558

Chen H, Zhu H, Yang J, Zhu Y, Mei J, Shen H, Liang K, Zhang X (2019) Role of programmed cell death 4 (PDCD4)-mediated Akt signaling pathway in vascular endothelial cell injury caused by lower-extremity ischemia-reperfusion in rats. Med Sci Monit 25:4811–4818. https://doi.org/10.12659/msm.914035

CAS  Article  PubMed  PubMed Central  Google Scholar 

Cheng Y, Liu X, Zhang S, Lin Y, Yang J, Zhang C (2009) MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4. J Mol Cell Cardiol 47(1):5–14. https://doi.org/10.1016/j.yjmcc.2009.01.008

CAS  Article  PubMed  PubMed Central  Google Scholar 

Chomova M, Zitnanova I (2016) Look into brain energy crisis and membrane pathophysiology in ischemia and reperfusion. Stress 19(4):341–348

CAS  Article  Google Scholar 

Di Y, Lei Y, Yu F, Changfeng F, Song W, Xuming M (2014) MicroRNAs expression and function in cerebral ischemia reperfusion injury. J Mol Neurosci 53(2):242–250. https://doi.org/10.1007/s12031-014-0293-8

CAS  Article  PubMed  Google Scholar 

Gu X, Dong M, Liu Z, Yang J, Shi Y (2020) MiR-499a-5p inhibits proliferation, invasion, migration, and epithelial-mesenchymal transition, and enhances radiosensitivity of cervical cancer cells via targeting eIF4E. Onco Targets Ther 13:2913–2924. https://doi.org/10.2147/ott.s241631

CAS  Article  PubMed  PubMed Central  Google Scholar 

He G, Xu W, Tong L, Li S, Su S, Tan X, Li C (2016) Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury. Apoptosis 21(4):390–403. https://doi.org/10.1007/s10495-016-1213-x

CAS  Article  PubMed  Google Scholar 

He S, Li Z, Yu Y, Zeng Q, Cheng Y, Ji W, Xia W, Lu S (2019) Exosomal miR-499a-5p promotes cell proliferation, migration and EMT via mTOR signaling pathway in lung adenocarcinoma. Exp Cell Res 379(2):203–213. https://doi.org/10.1016/j.yexcr.2019.03.035

CAS  Article  PubMed  Google Scholar 

Hu Y, Deng H, Xu S, Zhang J (2015) MicroRNAs regulate mitochondrial function in cerebral ischemia-reperfusion injury. Int J Mol Sci 16(10):24895–24917. https://doi.org/10.3390/ijms161024895

CAS  Article  PubMed  PubMed Central  Google Scholar 

Jia Z, Lian W, Shi H, Cao C, Han S, Wang K, Li M, Zhang X (2017) Ischemic postconditioning protects against intestinal ischemia/reperfusion injury via the HIF-1α/miR-21 axis. Sci Rep 7(1):16190. https://doi.org/10.1038/s41598-017-16366-6

CAS  Article  PubMed  PubMed Central  Google Scholar 

Liu J, Huang L, Su P, Song T, Zhang W, Fan J, Liu Y (2018a) MicroRNA-499a-5p inhibits osteosarcoma cell proliferation and differentiation by targeting protein phosphatase 1D through protein kinase B/glycogen synthase kinase 3β signaling. Oncol Lett 15(4):4113–4120. https://doi.org/10.3892/ol.2018.7814

CAS  Article  PubMed  PubMed Central  Google Scholar 

Liu Y, Eaton ED, Wills TE, McCann SK, Antonic A, Howells DW (2018b) Human ischaemic cascade studies using SH-SY5Y cells: a systematic review and meta-analysis. Transl Stroke Res 9(6):564–574. https://doi.org/10.1007/s12975-018-0620-4

Article  PubMed  PubMed Central  Google Scholar 

Liu K, Ma L, Zhou F, Yang Y, Hu HB, Wang L, Zhong L (2019) Identification of microRNAs related to myocardial ischemic reperfusion injury. J Cell Physiol 234(7):11380–11390. https://doi.org/10.1002/jcp.27795

CAS  Article  PubMed  Google Scholar 

Lopez-Neblina F, Toledo AH, Toledo-Pereyra LH (2005) Molecular biology of apoptosis in ischemia and reperfusion. J Invest Surg 18(6):335–350. https://doi.org/10.1080/08941930500328862

Article  PubMed  Google Scholar 

Luengo-Fernandez R, Gray AM, Bull L, Welch S, Cuthbertson F, Rothwell PM, Oxford Vascular S (2013) Quality of life after TIA and stroke: ten-year results of the Oxford Vascular Study. Neurology 81(18):1588–1595. https://doi.org/10.1212/WNL.0b013e3182a9f45f

Article  PubMed  PubMed Central  Google Scholar 

Machado NG, Alves MG, Carvalho RA, Oliveira PJ (2009) Mitochondrial involvement in cardiac apoptosis during ischemia and reperfusion: can we close the box? Cardiovasc Toxicol 9(4):211–227. https://doi.org/10.1007/s12012-009-9055-1

Article  PubMed  Google Scholar 

Matsuhashi S, Manirujjaman M, Hamajima H, Ozaki I (2019) Control mechanisms of the tumor suppressor PDCD4: expression and functions. Int J Mol Sci. https://doi.org/10.3390/ijms20092304

Article  PubMed  PubMed Central  Google Scholar 

Neshati V, Mollazadeh S, Fazly Bazzaz BS, de Vries AAF, Mojarrad M, Naderi-Meshkin H, Neshati Z, Mirahmadi M, Kerachian MA (2018) MicroRNA-499a-5p promotes differentiation of human bone marrow-derived mesenchymal stem cells to cardiomyocytes. Appl Biochem Biotechnol 186(1):245–255. https://doi.org/10.1007/s12010-018-2734-2

CAS  Article  PubMed  Google Scholar 

Rao G, Zhang W, Song S (2019) MicroRNA-217 inhibition relieves cerebral ischemia/reperfusion injury by targeting SIRT1. Mol Med Rep 20(2):1221–1229

CAS  PubMed  PubMed Central  Google Scholar 

Soejima H, Miyoshi O, Yoshinaga H, Masaki Z, Ozaki I, Kajiwara S, Niikawa N, Matsuhashi S, Mukai T (1999) Assignment of the programmed cell death 4 gene (PDCD4) to human chromosome band 10q24 by in situ hybridization. Cytogenet Cell Genet 87(1–2):113–114. https://doi.org/10.1159/000015408

CAS  Article  PubMed  Google Scholar 

Special report from the National Institute of Neurological Disorders and Stroke. Classification of cerebrovascular diseases III (1990). Stroke 21(4):637–676. https://doi.org/10.1161/01.str.21.4.637

Sun JC, Zheng B, Sun RX, Meng YK, Wang SM, Yang HS, Chen Y, Shi JG, Guo YF (2019) MiR-499a-5p suppresses apoptosis of human nucleus pulposus cells and degradation of their extracellular matrix by targeting SOX4. Biomed Pharmacother 113:108652. https://doi.org/10.1016/j.biopha.2019.108652

CAS  Article  PubMed  Google Scholar 

Tobin MK, Bonds JA, Minshall RD, Pelligrino DA, Testai FD, Lazarov O (2014) Neurogenesis and inflammation after ischemic stroke: what is known and where we go from here. J Cereb Blood Flow Metab 34(10):1573–1584. https://doi.org/10.1038/jcbfm.2014.130

Article  PubMed  PubMed Central  Google Scholar 

Yang G, Liu Z, Wang L, Chen X, Wang X, Dong Q, Zhang D, Yang Z, Zhou Q, Sun J, Xue L, Wang X, Gao M, Li L, Yi R, Ilgiz G, Ai J, Zhao S (2018) MicroRNA-195 protection against focal cerebral ischemia by targeting CX3CR1. J Neurosurg. https://doi.org/10.3171/2018.5.JNS173061

Article  PubMed  Google Scholar 

Yang Z, Li C, Fan XY, Liu LJ (2020) Circular RNA circ_0079593 promotes glioma development through regulating KPNA2 expression by sponging miR-499a-5p. Eur Rev Med Pharmacol Sci 24(3):1288–1301. https://doi.org/10.26355/eurrev_202001_20186

CAS  Article  PubMed  Google Scholar 

Yin KJ, Deng Z, Huang H, Hamblin M, Xie C, Zhang J, Chen YE (2010) miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia. Neurobiol Dis 38(1):17–26. https://doi.org/10.1016/j.nbd.2009.12.021

CAS  Article  PubMed  PubMed Central  Google Scholar 

Zhang Q, Zhang K, Zhang C, Ge H, Yin Y, Feng H, Hu R (2017) MicroRNAs as big regulators of neural stem/progenitor cell proliferation, differentiation and migration: a potential treatment for stroke. Curr Pharm Des 23(15):2252–2257

CAS  Article  Google Scholar 

Zhao L, Wang B, Zhang W, Sun L (2020) Effect of miR-499a-5p on damage of cardiomyocyte induced by hypoxia-reoxygenation via downregulating CD38 protein. J Cell Biochem 121(2):996–1004. https://doi.org/10.1002/jcb.29334

CAS  Article  PubMed  Google Scholar 

Zheng Y, Zhao P, Lian Y, Li S, Chen Y, Li L (2020) MiR-340-5p alleviates oxygen-glucose deprivation/reoxygenation-induced neuronal injury via PI3K/Akt activation by targeting PDCD4. Neurochem Int 134:104650. https://doi.org/10.1016/j.neuint.2019.104650

CAS  Article  PubMed  Google Scholar 

Zhong G, Long H, Ma S, Shunhan Y, Li J, Yao J (2019) miRNA-335-5p relieves chondrocyte inflammation by activating autophagy in osteoarthritis. Life Sci 226:164–172. https://doi.org/10.1016/j.lfs.2019.03.071

CAS  Article  PubMed  Google Scholar 

Zong Z, Song Y, Xue Y, Ruan X, Liu X, Yang C, Zheng J, Cao S, Li Z, Liu Y (2019) Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR-499a-5p/LMX1A/NLRC5 pathway. J Cell Mol Med 23(8):5048–5062. https://doi.org/10.1111/jcmm.14362

CAS  Article  PubMed  PubMed Central  Google Scholar 

Zuo X, Lu J, Manaenko A, Qi X, Tang J, Mei Q, Xia Y, Hu Q (2019) MicroRNA-132 attenuates cerebral injury by protecting blood–brain–barrier in MCAO mice. Exp Neurol 316:12–19. https://doi.org/10.1016/j.expneurol.2019.03.017

CAS  Article  PubMed  Google Scholar 

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