Supported by grants from the Japan Society for the Promotion of Science (15K09205, 18K08136, and 22K08250), intractable respiratory research grants from the Ibaraki Clinic and the Satoshi Okamura Memorial Foundation.

Author Contributions: Substantial contribution to the conception and design of the study: S.O. and M.K. Acquisition, analysis, and interpretation of the data in the study: S.O., M.K., D.S., M.O., T.H., T.N., H.N., C.I., and R.S.-K. Drafting the manuscript or revising it critically for important intellectual content: S.O., M.K., R.T., H.T., T.T., M.T., T.I., and H.O. Final approval of the version to be published: S.O., M.K., H.K., and Y.O. Agreement to be accountable for aspects of the work in addressing questions related to its accuracy: H.K. and Y.O.