Does Neutrophil-lymphocyte ratio correlate with the improvement of hepatosteatosis after laparoscopic sleeve gastrectomy?

Research Article

Open Access Gateway Yildirim K. · Karabicak İ. · Ulu E.K. · Aktimur R. · Gursel M.F. · Malazgirt Z.
Abstract

Introduction: Obesity is a disease that shortens life expectancy and predisposes to many diseases such as severe hepatosteatosis. Hepatosteatosis is characterized by inflammatory infiltration of the portal space. Bariatric surgery has improvement effect on hepatosteatosis and degree of inflammation. Laparoscopic sleeve gastrectomy is an effective and most common therapeutic option for obesity. Neutrophil-lymphocyte ratio is a parameter associated with inflammatory disease. This study aimed to investigate if there is any correlation between improvements in hepatosteatosis and biochemical parameters especially Neutrophil-lymphocyte ratio and ultrasonographic findings one year after the laparoscopic sleeve gastrectomy. Methods: The files of 66 patients who underwent laparoscopic sleeve gastrectomy between May 2017 and April 2020 were retrospectively reviewed. Preoperative and postoperative one year demographic data, biochemical and inflammatory parameters and ultrasonographic reports of the liver were reviewed. Results: A statistically significant improvement in hepatosteatosis was demonstrated by ultrasonography one year after laparoscopic sleeve gastrectomy. A significant decrease was also observed in Neutrophil-lymphocyte ratio. No correlation was found between the decrease of Neutrophil-lymphocyte ratio and improvement in hepatosteatosis. There was also significant difference between the preoperative and postoperative BMI, biochemical and inflammatory parameters. Conclusion: However we found laparoscopic sleeve gastrectomy is associated with significant improvement in hepatosteatosis and inflammatory parameters, no correlation between the improvement in hepatosteatosis and NLR was seen at one-year.

The Author(s). Published by S. Karger AG, Basel

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