Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis [Corrigendum]

Back to Journals » Journal of Hepatocellular Carcinoma » Volume 9

Authors Aydin Y, Koksal AR, Thevenot P, Chava S, Heidari Z, Lin D, Sandow T, Moroz K, Parsi MA, Scott J, Cohen A, Dash S

Received 16 August 2022

Accepted for publication 16 August 2022

Published 29 August 2022 Volume 2022:9 Pages 853—854

DOI https://doi.org/10.2147/JHC.S386422

Aydin Y, Koksal AR, Thevenot P, et al. J Hepatocell Carcinoma. 2020;15:1771–1786.

The authors have advised due to an error that occurred inadvertently at the time of figure assembly, Figure 3 on page 1587 is incorrect. The high magnification images of Huh-7.5 and HLE should be interchanged.

The correct Figure 3 is shown below.

Figure 3 Characterization of exosomes released from an autophagy-deficient and an autophagy-competent HCC cell line. (A) Cryogenic transmission electron microscopy (cryoTEM) images of exosomes purified from culture supernatants of autophagy-deficient (Huh-7.5) and autophagy-competent (HLE) HCC lines. Left panel (low magnification). Right panel (high magnification). (B) Top panel: Representative image of exosome Brownian motion in liquid phase using Nanoparticle tracking analysis (NTA). Bottom panel: Size distribution profile of exosomes with mean and mode of the population diameter ± standard error. (C) Exosome concentration in the culture supernatant quantified by NTA. The results are expressed as the mean ± standard deviation and analyzed by Student’s t-test. *P < 0.05. (D) Representative Western blot for TSG101 and CD9 in cell lysates and exosomes isolated from autophagy-deficient Huh-7.5 and autophagy-competent HLE cell cultures. All experiments were performed in triplicate.

The authors apologize for the error and advise it does not affect the results and conclusion of the paper.

Read the original article


Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

留言 (0)

沒有登入
gif