PHOX2B is a Sensitive and Specific Marker for the Histopathological Diagnosis of Pheochromocytoma and Paraganglioma

Mete O, Asa SL, Gill AJ, Kimura N, de Krijger RR, Tischler A (2022) Overview of the 2022 WHO Classification of Paragangliomas and Pheochromocytomas. Endocr Pathol 33: 90-114, https://doi.org/10.1007/s12022-022-09704-6

Article  PubMed  CAS  Google Scholar 

Lack EE (2007) Chapter 11 Extraadrenal paraganglia, paragangliomas, and other features of sympathoadrenal paragangliomas. In: Tumors of the adrenal glands and extraadrenal paraganglia. 4th edn. Washington, DC: ARP pp283–312.

Mamilla D, Manukyan I, Fetsch PA, Pacak K, Miettinen M (2020) Immunohistochemical distinction of paragangliomas from epithelial neuroendocrine tumors-gangliocytic duodenal and cauda equina paragangliomas align with epithelial neuroendocrine tumors. Hum Pathol 103: 72-82, https://doi.org/10.1016/j.humpath.2020.07.010

Article  PubMed  PubMed Central  CAS  Google Scholar 

Tsukada A, Ishizaki Y, Nobukawa B, Kawasaki S (2008) Paraganglioma of the pancreas: a case report and review of the literature. Pancreas 36: 214-216, https://doi.org/10.1097/01.MPA.0000311841.35183.45

Article  PubMed  Google Scholar 

Shibahara J, Goto A, Niki T, Tanaka M, Nakajima J, Fukayama M (2004) Primary pulmonary paraganglioma: report of a functioning case with immunohistochemical and ultrastructural study. Am J Surg Pathol 28: 825-829, https://doi.org/10.1097/01.pas.0000116832.81882.0b

Article  PubMed  Google Scholar 

Sakuma Y, Sata N, Endo K, Yasuda Y, Yokota S, Hosoya Y, Shimizu A, Fujii H, Matsubara D, Fukushima N, Asakawa S, Shimada YK, Lefor CK, Lefor AK (2017) An isolated metachronous metastasis to the adrenal gland from a pancreatic neuroendocrine tumor: A case report. Int J Surg Case Rep 41: 169-173, https://doi.org/10.1016/j.ijscr.2017.10.017

Article  PubMed  PubMed Central  Google Scholar 

Kimura N, Shiga K, Kaneko KI, Oki Y, Sugisawa C, Saito J, Tawara S, Akahori H, Sogabe S, Yamashita T, Takekoshi K, Naruse M, Katabami T (2021) Immunohistochemical Expression of Choline Acetyltransferase and Catecholamine-Synthesizing Enzymes in Head-and-Neck and Thoracoabdominal Paragangliomas and Pheochromocytomas. Endocr Pathol 32: 442-451, https://doi.org/10.1007/s12022-021-09694-x

Article  PubMed  CAS  Google Scholar 

Konosu-Fukaya S, Omata K, Tezuka Y, Ono Y, Aoyama Y, Satoh F, Fujishima F, Sasano H, Nakamura Y (2018) Catecholamine-Synthesizing Enzymes in Pheochromocytoma and Extraadrenal Paraganglioma. Endocr Pathol 29: 302-309 https://doi.org/10.1007/s12022-018-9544-5

Article  PubMed  CAS  Google Scholar 

Warren M, Matsuno R, Tran H, Shimada H (2018) Utility of Phox2b immunohistochemical stain in neural crest tumours and non-neural crest tumours in paediatric patients. Histopathology 72: 685-696, https://doi.org/10.1111/his.13412

Article  PubMed  Google Scholar 

Holland PW, Booth HA, Bruford EA (2007) Classification and nomenclature of all human homeobox genes. BMC Biol 5: 47, https://doi.org/10.1186/1741-7007-5-47

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bejarano PA, Baughman RP, Biddinger PW, Miller MA, Fenoglio-Preiser C, al-Kafaji B, Di Lauro R, Whitsett JA (1996) Surfactant proteins and thyroid transcription factor-1 in pulmonary and breast carcinomas. Mod Pathol 9: 445-452

PubMed  CAS  Google Scholar 

Barbareschi M, Murer B, Colby TV, Chilosi M, Macri E, Loda M, Doglioni C (2003) CDX-2 homeobox gene expression is a reliable marker of colorectal adenocarcinoma metastases to the lungs. Am J Surg Pathol 27: 141-149

Article  CAS  Google Scholar 

Ozcan A, Shen SS, Hamilton C, Anjana K, Coffey D, Krishnan B, Truong LD (2011) PAX 8 expression in non-neoplastic tissues, primary tumors, and metastatic tumors: a comprehensive immunohistochemical study. Mod Pathol 24: 751-764, https://doi.org/10.1038/modpathol.2011.3

Article  PubMed  CAS  Google Scholar 

Fagerberg L, Oksvold P, Skogs M, Algenas C, Lundberg E, Ponten F, Sivertsson A, Odeberg J, Klevebring D, Kampf C, Asplund A, Sjostedt E, Al-Khalili Szigyarto C, Edqvist PH, Olsson I, Rydberg U, Hudson P, Ottosson Takanen J, Berling H, Bjorling L, Tegel H, Rockberg J, Nilsson P, Navani S, Jirstrom K, Mulder J, Schwenk JM, Zwahlen M, Hober S, Forsberg M, von Feilitzen K, Uhlen M (2013) Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP). J Proteome Res 12: 2439-2448, https://doi.org/10.1021/pr300924j

Article  PubMed  CAS  Google Scholar 

Brunet JF, Pattyn A (2002) Phox2 genes - from patterning to connectivity. Curr Opin Genet Dev 12: 435-440, https://doi.org/10.1016/s0959-437x(02)00322-2

Article  PubMed  CAS  Google Scholar 

Lee JP, Hung YP, O'Dorisio TM, Howe JR, Hornick JL, Bellizzi AM (2017) Examination of PHOX2B in adult neuroendocrine neoplasms reveals relatively frequent expression in phaeochromocytomas and paragangliomas. Histopathology 71: 503-510, https://doi.org/10.1111/his.13243

Article  PubMed  PubMed Central  Google Scholar 

Nonaka D, Wang BY, Edmondson D, Beckett E, Sun CC (2013) A study of gata3 and phox2b expression in tumors of the autonomic nervous system. Am J Surg Pathol 37: 1236-1241, https://doi.org/10.1097/PAS.0b013e318289c765

Article  PubMed  Google Scholar 

Lambert SA, Jolma A, Campitelli LF, Das PK, Yin Y, Albu M, Chen X, Taipale J, Hughes TR, Weirauch MT (2018) The Human Transcription Factors. Cell 175: 598-599, https://doi.org/10.1016/j.cell.2018.09.045

Article  PubMed  CAS  Google Scholar 

Uhlen M, Fagerberg L, Hallstrom BM, Lindskog C, Oksvold P, Mardinoglu A, Sivertsson A, Kampf C, Sjostedt E, Asplund A, Olsson I, Edlund K, Lundberg E, Navani S, Szigyarto CA, Odeberg J, Djureinovic D, Takanen JO, Hober S, Alm T, Edqvist PH, Berling H, Tegel H, Mulder J, Rockberg J, Nilsson P, Schwenk JM, Hamsten M, von Feilitzen K, Forsberg M, Persson L, Johansson F, Zwahlen M, von Heijne G, Nielsen J, Ponten F (2015) Proteomics. Tissue-based map of the human proteome. Science 347: 1260419, https://doi.org/10.1126/science.1260419

Article  PubMed  CAS  Google Scholar 

Akobeng AK (2007) Understanding diagnostic tests 3: Receiver operating characteristic curves. Acta Paediatr 96: 644-647, https://doi.org/10.1111/j.1651-2227.2006.00178.x

Article  PubMed  Google Scholar 

Lenders JW, Duh QY, Eisenhofer G, Gimenez-Roqueplo AP, Grebe SK, Murad MH, Naruse M, Pacak K, Young WF, Jr. (2014) Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 99: 1915-1942, https://doi.org/10.1210/jc.2014-1498

Article  PubMed  CAS  Google Scholar 

Smith JD, Ellsperman SE, Basura GJ, Else T (2021) Re-evaluating the prevalence and factors characteristic of catecholamine secreting head and neck paragangliomas. Endocrinol Diabetes Metab 4: e00256, https://doi.org/10.1002/edm2.256

Article  PubMed  PubMed Central  CAS  Google Scholar 

Nurse CA, Piskuric NA (2013) Signal processing at mammalian carotid body chemoreceptors. Semin Cell Dev Biol 24: 22-30, https://doi.org/10.1016/j.semcdb.2012.09.006

Article  PubMed  CAS  Google Scholar 

Ramiro-Fuentes S, del-Marco A, Galan-Rodriguez B, Ramirez-Ponce P, Fernandez-Espejo E (2010) Morphophysiology of the Zuckerkandl's paraganglion: effects of dexamethasone and aging. Neurobiol Aging 31: 2115-2127, https://doi.org/10.1016/j.neurobiolaging.2008.12.001

Article  PubMed  CAS  Google Scholar 

Rockley TJ, Hawke M (1989) The glomus tympanicum: a middle ear chemoreceptor? J Otolaryngol 18: 370-373

PubMed  CAS  Google Scholar 

Dauger S, Pattyn A, Lofaso F, Gaultier C, Goridis C, Gallego J, Brunet JF (2003) Phox2b controls the development of peripheral chemoreceptors and afferent visceral pathways. Development 130: 6635-6642, https://doi.org/10.1242/dev.00866

Article  PubMed  CAS  Google Scholar 

Huber K, Karch N, Ernsberger U, Goridis C, Unsicker K (2005) The role of Phox2B in chromaffin cell development. Dev Biol 279: 501-508, https://doi.org/10.1016/j.ydbio.2005.01.007

Article  PubMed  CAS  Google Scholar 

Faragalla H, Weinreb I (2009) Olfactory neuroblastoma: a review and update. Adv Anat Pathol 16: 322-331, https://doi.org/10.1097/PAP.0b013e3181b544cf

Article  PubMed  CAS  Google Scholar 

Huilgol D, Tole S (2016) Cell migration in the developing rodent olfactory system. Cell Mol Life Sci 73: 2467-2490, https://doi.org/10.1007/s00018-016-2172-7

Article  PubMed  PubMed Central  CAS  Google Scholar 

Pattyn A, Morin X, Cremer H, Goridis C, Brunet JF (1999) The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature 399: 366-370,https://doi.org/10.1038/20700

Article  PubMed  CAS  Google Scholar 

Moriguchi T, Takako N, Hamada M, Maeda A, Fujioka Y, Kuroha T, Huber RE, Hasegawa SL, Rao A, Yamamoto M, Takahashi S, Lim KC, Engel JD (2006) Gata3 participates in a complex transcriptional feedback network to regulate sympathoadrenal differentiation. Development 133: 3871-3881, https://doi.org/10.1242/dev.02553

Article  PubMed  CAS  Google Scholar 

Miettinen M, McCue PA, Sarlomo-Rikala M, Rys J, Czapiewski P, Wazny K, Langfort R, Waloszczyk P, Biernat W, Lasota J, Wang Z (2014) GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors. Am J Surg Pathol 38: 13-22, https://doi.org/10.1097/PAS.0b013e3182a0218f

Article  PubMed  PubMed Central  Google Scholar 

Buffet A, Burnichon N, Favier J, Gimenez-Roqueplo AP (2020) An overview of 20 years of genetic studies in pheochromocytoma and paraganglioma. Best Pract Res Clin Endocrinol Metab 34: 101416, https://doi.org/10.1016/j.beem.2020.101416

Article  PubMed  CAS  Google Scholar 

Bourdeaut F, Trochet D, Janoueix-Lerosey I, Ribeiro A, Deville A, Coz C, Michiels JF, Lyonnet S, Amiel J, Delattre O (2005) Germline mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma. Cancer Lett 228: 51-58, https://doi.org/10.1016/j.canlet.2005.01.055

Article  PubMed  CAS  Google Scholar 

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