Correspondence to: Joseph Loscalzo, MD, PhD, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, 75 Francis St, Boston, MA 02115. Email

E-mail Address: [email protected]

https://orcid.org/0000-0002-1153-8047

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA (A.K.P., M.W.-W., W.X., S.Y., T.M., J.L.).