Barkus E, Stirling J, Hopkins R, Lewis S (2006) The presence of neurological soft signs along the psychosis proneness continuum. Schizophr Bull 32:573–577
PubMed PubMed Central Article Google Scholar
Barry H Jr (1945) Incidence of advanced maternal age in mothers of one thousand state hospital patients. Arch Neurol Psychiatry 54:186–191
Bassett AS, Scherer SW, Brzustowicz LM (2010) Copy number variations in schizophrenia: Critical review and new perspectives on concepts of genetics and disease. Am J Psychiatry 167:899–914
PubMed PubMed Central Article Google Scholar
Belvederi Murri M, Pariante CM, Dazzan P, Hepgul N, Papadopoulos AS, Zunszain P, Di Forti M, Murray RM, Mondelli V (2012) Hypothalamic-pituitary-adrenal axis and clinical symptoms in first-episode psychosis. Psychoneuroendocrinology 37:629–644
CAS PubMed Article Google Scholar
Bingley PJ, Douek IF, Rogers CA, Gale EA (2000) Influence of maternal age at delivery and birth order on risk of type 1 diabetes in childhood: Prospective population based family study Bart’s-oxford family study group. BMJ 321:420–424
CAS PubMed PubMed Central Article Google Scholar
Boks MP, Liddle PF, Burgerhof JG, Knegtering R, van den Bosch RJ (2004) Neurological soft signs discriminating mood disorders from first episode schizophrenia. Acta Psychiatr Scand 110:29–35
CAS PubMed Article Google Scholar
Bombin I, Arango C, Buchanan RW (2005) Significance and meaning of neurological signs in schizophrenia: Two decades later. Schizophr Bull 31:962–977
Bosch M, Rajmil O, Egozcue J, Templado C (2003) Linear increase of structural and numerical chromosome 9 abnormalities in human sperm regarding age. Eur J Hum Genet EJHG 11:754–759
CAS PubMed Article Google Scholar
Bray I, Gunnell D, Davey Smith G (2006) Advanced paternal age: How old is too old? J Epidemiol Comm Health 60:851–853
Brown AS, Schaefer CA, Wyatt RJ, Begg MD, Goetz R, Bresnahan MA, Harkavy-Friedman J, Gorman JM, Malaspina D, Susser ES (2002) Paternal age and risk of schizophrenia in adult offspring. Am J Psychiatry 159:1528–1533
PubMed PubMed Central Article Google Scholar
Buchanan RW, Heinrichs DW (1989) The neurological evaluation scale (nes): A structured instrument for the assessment of neurological signs in schizophrenia. Psychiatry Res 27:335–350
CAS PubMed Article Google Scholar
Buchanan RW, Koeppl P, Breier A (1994) Stability of neurological signs with clozapine treatment. Biol Psychiatry 36:198–200
CAS PubMed Article Google Scholar
Buizer-Voskamp JE, Laan W, Staal WG, Hennekam EA, Aukes MF, Termorshuizen F, Kahn RS, Boks MP, Ophoff RA (2011) Paternal age and psychiatric disorders: Findings from a dutch population registry. Schizophr Res 129:128–132
PubMed PubMed Central Article Google Scholar
Byrne M, Agerbo E, Ewald H, Eaton WW, Mortensen PB (2003) Parental age and risk of schizophrenia: A case-control study. Arch Gen Psychiatry 60:673–678
Cannon M (2009) Contrasting effects of maternal and paternal age on offspring intelligence: The clock ticks for men too. PLoS Med 6:e42
Chan MK, Krebs MO, Cox D, Guest PC, Yolken RH, Rahmoune H, Rothermundt M, Steiner J, Leweke FM, van Beveren NJ, Niebuhr DW, Weber NS, Cowan DN, Suarez-Pinilla P, Crespo-Facorro B, Mam-Lam-Fook C, Bourgin J, Wenstrup RJ, Kaldate RR, Cooper JD, Bahn S (2015) Development of a blood-based molecular biomarker test for identification of schizophrenia before disease onset. Transl Psychiatry 5:e601
CAS PubMed PubMed Central Article Google Scholar
Chan RC, Gottesman II (2008) Neurological soft signs as candidate endophenotypes for schizophrenia: A shooting star or a northern star? Neurosci Biobehav Rev 32:957–971
Chan RC, Wang Y, Zhao Q, Yan C, Xu T, Gong QY, Manschreck TC (2010) Neurological soft signs in individuals with schizotypal personality features. Aust N Z J Psychiatry 44:800–804
Chan RC, Xie W, Geng FL, Wang Y, Lui SS, Wang CY, Yu X, Cheung EF, Rosenthal R (2016) Clinical utility and lifespan profiling of neurological soft signs in schizophrenia spectrum disorders. Schizophr Bull 42:560–570
Chan RC, Xu T, Heinrichs RW, Yu Y, Gong QY (2010) Neurological soft signs in non-psychotic first-degree relatives of patients with schizophrenia: A systematic review and meta-analysis. Neurosci Biobehav Rev 34:889–896
Chan RC, Xu T, Heinrichs RW, Yu Y, Wang Y (2010) Neurological soft signs in schizophrenia: A meta-analysis. Schizophr Bull 36:1089–1104
Chen EY, Hui CL, Chan RC, Dunn EL, Miao MY, Yeung WS, Wong CK, Chan WF, Tang WN (2005) A 3-year prospective study of neurological soft signs in first-episode schizophrenia. Schizophr Res 75:45–54
Compton MT, Bercu Z, Bollini A, Walker EF (2006) Factor structure of the neurological evaluation scale in a predominantly african american sample of patients with schizophrenia, unaffected relatives, and non-psychiatric controls. Schizophr Res 84:365–377
Corvin A, Morris DW (2014) Genome-wide association studies: Findings at the major histocompatibility complex locus in psychosis. Biol Psychiatry 75:276–283
CAS PubMed Article Google Scholar
Cross-Disorder Group of the Psychiatric Genomics C (2013) Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis. Lancet 381:1371–1379
Crow JF (2003) Development. There’s something curious about paternal-age effects. Science 301:606–607
CAS PubMed Article Google Scholar
Crow JF (1997) The high spontaneous mutation rate: Is it a health risk? Proc Natl Acad Sci U S A 94:8380–8386
CAS PubMed PubMed Central Article Google Scholar
Crow JF (2000) The origins, patterns and implications of human spontaneous mutation. Nat Rev Genet 1:40–47
CAS PubMed Article Google Scholar
Cuthbert BN (2015) Research domain criteria: Toward future psychiatric nosologies. Dialogues Clin Neurosci 17:89–97
PubMed PubMed Central Article Google Scholar
Dalman C (2009) Advanced paternal age increases risk of bipolar disorder in offspring. Evid Based Ment Health 12:59
Dalman C, Allebeck P (2002) Paternal age and schizophrenia: Further support for an association. Am J Psychiatry 159:1591–1592
Dazzan P, Lloyd T, Morgan KD, Zanelli J, Morgan C, Orr K, Hutchinson G, Fearon P, Allin M, Rifkin L, McGuire PK, Doody GA, Holloway J, Leff J, Harrison G, Jones PB, Murray RM (2008) Neurological abnormalities and cognitive ability in first-episode psychosis. Br J Psychiatry 193:197–202
Dazzan P, Morgan KD, Orr KG, Hutchinson G, Chitnis X, Suckling J, Fearon P, Salvo J, McGuire PK, Mallett RM, Jones PB, Leff J, Murray RM (2004) The structural brain correlates of neurological soft signs in aesop first-episode psychoses study. Brain 127:143–153
Dockerty JD, Draper G, Vincent T, Rowan SD, Bunch KJ (2001) Case-control study of parental age, parity and socioeconomic level in relation to childhood cancers. Int J Epidemiol 30:1428–1437
CAS PubMed Article Google Scholar
Docx L, Morrens M, Bervoets C, Hulstijn W, Fransen E, De Hert M, Baeken C, Audenaert K, Sabbe B (2012) Parsing the components of the psychomotor syndrome in schizophrenia. Acta Psychiatr Scand 126:256–265
CAS PubMed Article Google Scholar
Drake JW, Charlesworth B, Charlesworth D, Crow JF (1998) Rates of spontaneous mutation. Genetics 148:1667–1686
CAS PubMed PubMed Central Article Google Scholar
Ek M, Wicks S, Svensson AC, Idring S, Dalman C (2015) Advancing paternal age and schizophrenia: The impact of delayed fatherhood. Schizophr Bull 41:708–714
Ekeus C, Olausson PO, Hjern A (2006) Psychiatric morbidity is related to parental age: A national cohort study. Psychol Med 36:269–276
El-Saadi O, Pedersen CB, McNeil TF, Saha S, Welham J, O’Callaghan E, Cantor-Graae E, Chant D, Mortensen PB, McGrath J (2004) Paternal and maternal age as risk factors for psychosis: Findings from denmark, sweden and australia. Schizophr Res 67:227–236
Flatscher-Bader T, Foldi CJ, Chong S, Whitelaw E, Moser RJ, Burne TH, Eyles DW, McGrath JJ (2011) Increased de novo copy number variants in the offspring of older males. Transl Psychiatry 1:e34
留言 (0)