HIV Prevention Tools Across the Pregnancy Continuum: What Works, What Does Not, and What Can We Do Differently?

UNAIDS D. UNAIDS 2020 Global Report, UNAIDS Joint United Nations Programme on HIV. Geneva: AIDS; 2020.

Rosenberg NE, et al. Empirical estimates of adult HIV incidence across 12 countries in sub-Saharan Africa. in CROI. 2022.

Dinh T-H, et al. Impact of maternal HIV seroconversion during pregnancy on early mother to child transmission of HIV (MTCT) measured at 4–8 weeks postpartum in South Africa 2011–2012: a national population-based evaluation. PLoS One. 2015;10(5):e0125525–e0125525.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Tessema ZT, et al. Determinants of accessing healthcare in Sub-Saharan Africa: a mixed-effect analysis of recent demographic and health surveys from 36 countries. BMJ Open. 2022;12(1):e054397–e054397.

PubMed  PubMed Central  Article  Google Scholar 

WHO, Preventing HIV during pregnancy and breastfeeding in the context of PrEP. 2017, World Health Organization: Geneva, Switzerland.

Worku MG, Teshale AB, Tesema GA. Prevalence and associated factors of HIV testing among pregnant women: a multilevel analysis using the recent demographic and health survey data from 11 East African countries. HIV/AIDS (Auckland, N.Z.) 2021;13:181–189.

Awopegba OE, et al. Prenatal care coverage and correlates of HIV testing in sub-Saharan Africa: insight from demographic and health surveys of 16 countries. PLoS One. 2020;15(11): e0242001.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Bolu OO, et al. Approaches for scaling up human immunodeficiency virus testing and counseling in prevention of mother-to-child human immunodeficiency virus transmission settings in resource-limited countries. Am J Obstet Gynecol. 2007;197(3):S83–9.

PubMed  Article  Google Scholar 

Ndege S, et al. HIV prevalence and antenatal care attendance among pregnant women in a large home-based HIV counseling and testing program in Western Kenya. PLoS One. 2016;11(1): e0144618.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Nakanwagi M, et al. Low proportion of women who came knowing their HIV status at first antenatal care visit, Uganda, 2012–2016: a descriptive analysis of surveillance data. BMC Pregnancy Childbirth. 2020;20(1):498.

PubMed  PubMed Central  Article  Google Scholar 

Joseph Davey D, et al. Sexual risk during pregnancy and postpartum periods among HIV-infected and -uninfected South African women: implications for primary and secondary HIV prevention interventions. PLoS One. 2018;13(3):e0192982–e0192982.

PubMed  PubMed Central  Article  CAS  Google Scholar 

Thomson K, et al. Increased risk of female HIV-1 acquisition throughout pregnancy and postpartum: a prospective per-coital act analysis among women with HIV-1 infected partners. J Infect Dis. 2018.

Moller A-B, et al. Early antenatal care visit: a systematic analysis of regional and global levels and trends of coverage from 1990 to 2013. Lancet Glob Health. 2017;5(10):e977–83.

PubMed  PubMed Central  Article  Google Scholar 

Munthali M, et al. Knowledge and perceptions of preconception care among health workers and women of reproductive age in Mzuzu City, Malawi: a cross-sectional study. Reprod Health. 2021;18(1):229.

PubMed  PubMed Central  Article  Google Scholar 

Teshome F, et al. What do women know before getting pregnant? Knowledge of preconception care and associated factors among pregnant women in Mana district, Southwest Ethiopia: a community-based cross-sectional study. BMJ Open. 2020;10(7): e035937.

PubMed  PubMed Central  Article  Google Scholar 

Dean SV, et al. Born too soon: care before and between pregnancy to prevent preterm births: from evidence to action. Reprod Health. 2013;10(1):1–16.

Article  Google Scholar 

Mugambi ML, et al. Design and evaluation of strategies to implement HIV prevention interventions for pregnant women in community pharmacy settings in western Kenya: a mixed-methods study protocol. BMJ Open. 2021;11(12): e052311.

PubMed  PubMed Central  Article  Google Scholar 

Pintye J, et al. A risk assessment tool for identifying pregnant and postpartum women who may benefit from preexposure prophylaxis. Clin Infect Dis. 2017;64(6):751–8.

PubMed  Google Scholar 

Balkus JE, et al. An empiric HIV risk scoring tool to predict HIV-1 acquisition in African women. J Acquir Immune Defic Syndr. (1999), 2016;72(3):333.

Kahle EM, et al. An empiric risk scoring tool for identifying high-risk heterosexual HIV-1 serodiscordant couples for targeted HIV-1 prevention. J Acquir Immune Defic Syndr. (1999), 2013;62(3):339.

Coates TJ, Richter L, Caceres C. Behavioural strategies to reduce HIV transmission: how to make them work better. The Lancet. 2008;372(9639):669–84.

Article  Google Scholar 

Organization, W.H. Prevention of mother-to-child transmission (PMTCT). Briefing Note. Geneva: Department of HIV/AIDS, 2007.

World Health Organization, Guidance on couples HIV testing and counselling including antiretroviral therapy for treatment and prevention in serodiscordant couples: recommendations for a public health approach. 2012.

Orne-Gliemann J, et al. Couple-oriented prenatal HIV counseling for HIV primary prevention: an acceptability study. BMC Public Health. 2010;10(1):197.

PubMed  PubMed Central  Article  Google Scholar 

Clark J, et al. Improving male involvement in antenatal care in low and middle-income countries to prevent mother to child transmission of HIV: A realist review. PLoS One. 2020;15(10):e0240087–e0240087.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Cornell M, et al. HIV services in sub-Saharan Africa: the greatest gap is men. The Lancet. 2021;397(10290):2130–2.

Article  Google Scholar 

Giguère K, et al. Trends in knowledge of HIV status and efficiency of HIV testing services in sub-Saharan Africa, 2000–20: a modelling study using survey and HIV testing programme data. The Lancet HIV. 2021;8(5):e284–93.

PubMed  PubMed Central  Article  Google Scholar 

Mohlala BK, Boily MC, Gregson S. The forgotten half of the equation: randomized controlled trial of a male invitation to attend couple voluntary counselling and testing. AIDS. 2011;25(12):1535–41.

PubMed  Article  Google Scholar 

Homsy J, et al. Primary HIV prevention in pregnant and lactating Ugandan women: a randomized trial. PLoS One. 2019;14(2): e0212119.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Choko AT, et al. Partner-delivered HIV self-test kits with and without financial incentives in antenatal care and index patients with HIV in Malawi: a three-arm, cluster-randomised controlled trial. Lancet Global Health. 2021;9(7):e977–e988. This three-arm cluster randomized trial in Malawi found an increase in HIV testing rates among male partners who received HIV self-tests from pregnant women attending antenatal care.

Masters SH, et al. Promoting partner testing and couples testing through secondary distribution of HIV self-tests: a randomized clinical trial. PLoS Med. 2016;13(11): e1002166.

PubMed  PubMed Central  Article  Google Scholar 

Choko AT, et al. Partner-delivered HIV self-test kits with and without financial incentives in antenatal care and index patients with HIV in Malawi: a three-arm, cluster-randomised controlled trial. Lancet Glob Health. 2021;9(7):e977–88.

PubMed  PubMed Central  Article  Google Scholar 

Hershow RB, et al. Perspectives on HIV partner notification, partner HIV self-testing and partner home-based HIV testing by pregnant and postpartum women in antenatal settings: a qualitative analysis in Malawi and Zambia. J Int AIDS Soc. 2019;22: e25293.

PubMed  PubMed Central  Article  Google Scholar 

Korte JE, et al. HIV testing preferences among pregnant women attending antenatal care and their male partners: a discrete choice experiment in Uganda. Afr J AIDS Res. 2019;18(4):332–40.

PubMed  PubMed Central  Article  Google Scholar 

Ngumbau NM. HIVST acceptance and PrEP initiation among pregnant women at high risk of HIV in Homa Bay and Siaya counties, Kenya. 2021.

Jamil MS, et al. Examining the effects of HIV self-testing compared to standard HIV testing services in the general population: a systematic review and meta-analysis. EClinicalMedicine. 2021;38: 100991.

PubMed  PubMed Central  Article  Google Scholar 

Sibanda EL, Mavhu W. Secondary HIV self-test distribution increases male partner testing. Lancet Glob Health. 2021;9(12):e1632–3.

PubMed  Article  Google Scholar 

Fleming DT, Wasserheit JN. From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection. Sexually transmitted infections. 1999;75(1):3–17.

CAS  PubMed  PubMed Central  Article  Google Scholar 

World Health Organization. Global guidance on criteria and processes for validation: elimination of mother-to-child transmission (EMTCT) of HIV and syphilis. WHO, Editor. Geneva, Switzerland; 2014.

Swartzendruber A, et al. Introduction of rapid syphilis testing in antenatal care: a systematic review of the impact on HIV and syphilis testing uptake and coverage. Int J Gynaecol Obstet. 2015;130(Suppl 1):S15-21.

PubMed  PubMed Central  Article  Google Scholar 

Korenromp EL, et al. Global burden of maternal and congenital syphilis and associated adverse birth outcomes—estimates for 2016 and progress since 2012. PLoS One. 2019;14(2): e0211720.

CAS  PubMed  PubMed Central  Article  Google Scholar 

Low N, et al. Global control of sexually transmitted infections. Lancet. 2006;368(9551):2001–16.

PubMed  Article  Google Scholar 

Joseph Davey DL, et al. Prevalence of curable sexually transmitted infections in pregnant women in low- and middle-income countries from 2010 to 2015: a systematic review. Sex Transm Dis. 2016;43(7):450–8.

CAS  PubMed  Article  Google Scholar 

Looker KJ, et al. First estimates of the global and regional incidence of neonatal herpes infection. Lancet Glob Health. 2017;5(3):e300–9.

PubMed  PubMed Central  Article  Google Scholar 

World Health Organization. Guidelines for the management of sexually transmitted infections. Revised 2003. WHO Library Cataloguing-in-Publication Data. Geneva, Switzerland.

Mlisana K, et al. Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa. J Infect Dis. 2012;206(1):6–14.

PubMed  PubMed Central  Article  Google Scholar 

Bosu WK. Syndromic management of sexually transmitted diseases: is it rational or scientific? Trop Med Int Health. 1999;4(2):114–9.

CAS  PubMed  Article  Google Scholar 

Vuylsteke B. Current status of syndromic management of sexually transmitted infections in developing countries. Sex Transm Infect. 2004;80(5):333–4.

CAS  PubMed  PubMed Central  Article  Google Scholar 

White RG, et al. Low effectiveness of syndromic treatment services for curable sexually transmitted infections in rural South Africa. Sex Transm Infect. 2008;84(7):528–34.

CAS  PubMed 

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