Recent advances in polysaccharide-based in situ forming hydrogels

ElsevierVolume 70, October 2022, 102200Current Opinion in Chemical BiologyAbstract

Polysaccharides comprise an important class of natural polymers; they are abundant, diverse, polyfunctional, typically benign, and are biodegradable. Using polysaccharides to design in situ forming hydrogels is an attractive and important field of study since many polysaccharide-based hydrogels exhibit desirable characteristics including self-healing, responsiveness to environmental stimuli, and injectability. These characteristics are particularly useful for biomedical applications. This review will discuss recent discoveries in polysaccharide-based in situ forming hydrogels, including network architecture designs, curing mechanisms, physical and chemical properties, and potential applications.

Keywords

Polysaccharides

Hydrogels

Self-healing

Biodegradable

In situ forming

Injectable

Benign

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