Inhibition of ANXA2 regulated by SRF attenuates the development of severe acute pancreatitis by inhibiting the NF-κB signaling pathway

Tang GX, et al. MiR-20b-5p modulates inflammation, apoptosis and angiogenesis in severe acute pancreatitis through autophagy by targeting AKT3. Autoimmunity. 2021;54(7):460–70.

CAS  Article  Google Scholar 

Boxhoorn L, et al. Acute pancreatitis. Lancet. 2020;396(10252):726–34.

Article  Google Scholar 

Banks PA, et al. Classification of acute pancreatitis–2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62(1):102–11.

Article  Google Scholar 

Trikudanathan G, et al. Current concepts in severe acute and necrotizing pancreatitis: an evidence-based approach. Gastroenterology. 2019;156(7):1994-2007.e3.

Article  Google Scholar 

Maheshwari R, Subramanian RM. Severe acute pancreatitis and necrotizing pancreatitis. Crit Care Clin. 2016;32(2):279–90.

Article  Google Scholar 

Munir F, et al. Advances in immunomodulatory therapy for severe acute pancreatitis. Immunol Lett. 2020;217:72–6.

CAS  Article  Google Scholar 

Christensen MV, et al. Annexin A2 and cancer: a systematic review. Int J Oncol. 2018;52(1):5–18.

CAS  PubMed  Google Scholar 

Dallacasagrande V, Hajjar KA. Annexin A2 in inflammation and host defense. Cells. 2020;9(6):1499.

CAS  Article  Google Scholar 

Zhang S, et al. Annexin A2 binds to endosomes and negatively regulates TLR4-triggered inflammatory responses via the TRAM-TRIF pathway. Sci Rep. 2015;5:15859.

CAS  Article  Google Scholar 

Zhao D, et al. The interaction between ANXA2 and lncRNA Fendrr promotes cell apoptosis in caerulein-induced acute pancreatitis. J Cell Biochem. 2019;120(5):8160–8.

CAS  Article  Google Scholar 

Kalita K, Kuzniewska B, Kaczmarek L. MKLs: co-factors of serum response factor (SRF) in neuronal responses. Int J Biochem Cell Biol. 2012;44(9):1444–7.

CAS  Article  Google Scholar 

Miano JM. Role of serum response factor in the pathogenesis of disease. Lab Invest. 2010;90(9):1274–84.

CAS  Article  Google Scholar 

Miralles F, et al. Conditional inactivation of the murine serum response factor in the pancreas leads to severe pancreatitis. Lab Invest. 2006;86(10):1020–36.

CAS  Article  Google Scholar 

Zhou X, et al. Socs1 and Socs3 degrades Traf6 via polyubiquitination in LPS-induced acute necrotizing pancreatitis. Cell Death Dis. 2015;6: e2012.

CAS  Article  Google Scholar 

Zhao Q, et al. Melatonin attenuates endoplasmic reticulum stress in acute pancreatitis. Pancreas. 2018;47(7):884–91.

CAS  Article  Google Scholar 

Murphy AJ, Guyre PM, Pioli PA. Estradiol suppresses NF-kappa B activation through coordinated regulation of let-7a and miR-125b in primary human macrophages. J Immunol. 2010;184(9):5029–37.

CAS  Article  Google Scholar 

Demols A, et al. Endogenous interleukin-10 modulates fibrosis and regeneration in experimental chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2002;282(6):G1105–12.

CAS  Article  Google Scholar 

Jacob TG, et al. Duration of injury correlates with necrosis in caerulein-induced experimental acute pancreatitis: implications for pathophysiology. Int J Exp Pathol. 2014;95(3):199–208.

CAS  Article  Google Scholar 

Deng YW, Shu YG, Sun SL. LncRNA PART1 inhibits glioma proliferation and migration via miR-374b/SALL1 axis. Neurochem Int. 2022;157:105347.

CAS  Article  Google Scholar 

Joy M, et al. The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms. J Biol Chem. 2017;292(28):11777–91.

CAS  Article  Google Scholar 

Wang Y, et al. Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-kappaB signaling pathway. Am J Physiol Cell Physiol. 2019;316(2):C223–34.

CAS  Article  Google Scholar 

Ismail OZ, Bhayana V. Lipase or amylase for the diagnosis of acute pancreatitis? Clin Biochem. 2017;50(18):1275–80.

CAS  Article  Google Scholar 

Defour A, et al. Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle. Hum Mol Genet. 2017;26(11):1979–91.

CAS  Article  Google Scholar 

Lei Y, et al. Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice. Clin Sci. 2019;133(7):789–804.

CAS  Article  Google Scholar 

Renner B, et al. Annexin A2 enhances complement activation by inhibiting factor H. J Immunol. 2016;196(3):1355–65.

CAS  Article  Google Scholar 

Ma L, Yu Y, Qu X. Suppressing serum response factor inhibits invasion in cervical cancer cell lines via regulating Egr1 and epithelial-mesenchymal transition. Int J Mol Med. 2019;43(1):614–20.

CAS  PubMed  Google Scholar 

Sisson TH, et al. Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis. Am J Pathol. 2015;185(4):969–86.

CAS  Article  Google Scholar 

Dai X, et al. SM22alpha suppresses cytokine-induced inflammation and the transcription of NF-kappaB inducing kinase (Nik) by modulating SRF transcriptional activity in vascular smooth muscle cells. PLoS ONE. 2017;12(12): e0190191.

Article  Google Scholar 

Xu D, et al. miR-22 contributes to endosulfan-induced endothelial dysfunction by targeting SRF in HUVECs. Toxicol Lett. 2017;269:33–40.

CAS  Article  Google Scholar 

Wang Y, et al. Annexin A2 could enhance multidrug resistance by regulating NF-kappaB signaling pathway in pediatric neuroblastoma. J Exp Clin Cancer Res. 2017;36(1):111.

Article  Google Scholar 

Scott O, Roifman CM. NF-kappaB pathway and the Goldilocks principle: lessons from human disorders of immunity and inflammation. J Allergy Clin Immunol. 2019;143(5):1688–701.

Article  Google Scholar 

Hou C, et al. Iguratimod (T-614) attenuates severe acute pancreatitis by inhibiting the NLRP3 inflammasome and NF-kappaB pathway. Biomed Pharmacother. 2019;119: 109455.

CAS  Article  Google Scholar 

Chen X, Song D. LncRNA MEG3 participates in caerulein-induced inflammatory injury in human pancreatic cells via regulating miR-195-5p/FGFR2 axis and inactivating NF-kappaB pathway. Inflammation. 2021;44(1):160–73.

CAS  Article  Google Scholar 

Mo XJ, Ye XZ, Li YP. Effects of euphorbia kansui on the serum levels of IL-6, TNF-alpha, NF-kappaB, sTNFR and IL-8 in patients with severe acute pancreatitis. J Biol Regul Homeost Agents. 2019;33(2):469–75.

CAS  PubMed  Google Scholar 

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