Hypertension and clinical outcomes in patients with familial hypercholesterolemia

Cardiovascular Metabolic Center, State Key Laboratory of Cardiovascular Diseases, Fu Wai Hospital, National Clinical Research Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Correspondence to Jian-Jun Li, MD, PhD, FESC, FACC, Cardiovascular Metabolic Center, State Key Laboratory of Cardiovascular Diseases, Fu Wai Hospital, National Clinical Research Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 BeiLiShi Road, XiCheng District, Beijing 100037, China. Tel: +86 10 88396077; fax: +86 10 68331730; e-mail: [email protected]

Abbreviations: APOB, apolipoprotein B gene; ASCVD, atherosclerosis cardiovascular disease; BP, blood pressure; CAD, coronary artery disease; CI, confidential interval; CVD, cardiovascular disease; CVEs, cardiovascular events; DLCN, Lipid Clinic Network criteria; HDL-C, high-density lipoprotein cholesterol; HeFH, heterozygous familial hypercholesterolemia; LDL-C, low-density lipoprotein cholesterol; LDLR, low-density lipoprotein receptor gene; MI, myocardial infarction; PCSK9, proprotein convertase subtilisin/kexin type 9gene; T2DM, type 2 diabetes mellitus

Received 16 November, 2021

Revised 28 March, 2022

Accepted 20 April, 2022

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