Quinlan, J.I.; Maganaris, C.N.; Franchi, M. v.; Smith, K.; Atherton, P.J.; Szewczyk, N.J.; Greenhaff, P.L.; Phillips, B.E.; Blackwell, J.I.; Boereboom, C.; et al. Muscle and tendon contributions to reduced rate of torque development in healthy older males. J Gerontol - Series A Biol Sci Med Sci 2018. https://doi.org/10.1093/gerona/glx149.
Svensson RB, Heinemeier KM, Couppé C, Kjaer M, Magnusson SP. Effect of aging and exercise on the tendon. J Appl Physiol. 2016;121:1353–62.
Tuite DJ, Renström PAFH, O’Brien M. The aging tendon. Scand J Med Sci Sports. 2007;7:72–7. https://doi.org/10.1111/j.1600-0838.1997.tb00122.x.
Birch HL, Peffers MJ, Clegg PD. Influence of ageing on tendon homeostasis. Adv Exp Med Biol. 2016;920:247–60.
Tsai WC, Chang HN, Yu TY, Chien CH, Fu LF, Liang FC, Pang JHS. Decreased proliferation of aging tenocytes is associated with down-regulation of cellular senescence-inhibited gene and up-regulation of P27. J Orthop Res. 2011;29:1598–603. https://doi.org/10.1002/jor.21418.
CAS Article PubMed Google Scholar
Zhang J, Wang JHC (2015) Moderate exercise mitigates the detrimental effects of aging on tendon stem cells. PLoS One 10. https://doi.org/10.1371/journal.pone.0130454.
Kostrominova TY, Brooks Sv. Age-related changes in structure and extracellular matrix protein expression levels in rat tendons. Age (Omaha). 2013;35:2203–14. https://doi.org/10.1007/s11357-013-9514-2.
Dunkman AA, Buckley MR, Mienaltowski MJ, Adams SM, Thomas SJ, Satchell L, Kumar A, Pathmanathan L, Beason DP, Iozzo Rv, et al. Decorin expression is important for age-related changes in tendon structure and mechanical properties. Matrix Biol. 2013;32:3–13. https://doi.org/10.1016/j.matbio.2012.11.005.
CAS Article PubMed Google Scholar
Peffers, M.J.; Fang, Y.; Cheung, K.; Wei, T.K.J.; Clegg, P.D.; Birch, H.L. Transcriptome analysis of ageing in uninjured human achilles tendon. Arthritis Res Ther 2015, 17. https://doi.org/10.1186/s13075-015-0544-2.
Heinemeier KM, Skovgaard D, Bayer ML, Qvortrup K, Kjaer A, Kjaer M, Magnusson SP, Kongsgaard M. Uphill running improves rat Achilles tendon tissue mechanical properties and alters gene expression without inducing pathological changes. J Appl Physiol. 2012;113:827–36. https://doi.org/10.1152/japplphysiol.00401.2012.
CAS Article PubMed Google Scholar
Sullivan BE, Carroll CC, Jemiolo B, Trappe SW, Magnusson SP, Døssing S, Kjaer M, Trappe TA. Effect of acute resistance exercise and sex on human patellar tendon structural and regulatory MRNA expression. J Appl Physiol. 2009;106:468–75. https://doi.org/10.1152/japplphysiol.91341.2008.
CAS Article PubMed Google Scholar
Heinemeier, KM.; Bjerrum, SS.; Schjerling, P.; Kjaer, M. Expression of extracellular matrix components and related growth factors in human tendon and muscle after acute exercise. Scand J Med Sci Sports 2013, 23. https://doi.org/10.1111/j.1600-0838.2011.01414.x.
Marqueti RC, Durigan JLQ, Oliveira AJS, Mekaro MS, Guzzoni V, Aro AA, Pimentel ER, Selistre-De-Araujo HS. Effects of aging and resistance training in rat tendon remodeling. FASEB J. 2018;32:353–68. https://doi.org/10.1096/fj.201700543R.
CAS Article PubMed Google Scholar
Wood LK, Brooks Sv. Ten weeks of treadmill running decreases stiffness and increases collagen turnover in tendons of old mice. J Orthop Res. 2016;34:346–53. https://doi.org/10.1002/jor.22824.
CAS Article PubMed Google Scholar
Xu SY, Bin He Y, Deng SY, Liu SY, Xu L, Ni GX. Intensity-dependent effect of treadmill running on rat Achilles tendon. Exp Ther Med. 2018;15(5377):5383. https://doi.org/10.3892/etm.2018.6084.
Heinemeier KM, Olesen JL, Schjerling P, Haddad F, Langberg H, Baldwin KM, Kjaer M. Short-term strength training and the expression of myostatin and IGF-I isoforms in rat muscle and tendon: differential effects of specific contraction types. J Appl Physiol. 2007;102:573–81. https://doi.org/10.1152/japplphysiol.00866.2006.
CAS Article PubMed Google Scholar
Heinemeier KM, Olesen JL, Haddad F, Langberg H, Kjaer M, Baldwin KM, Schjerling P. Expression of collagen and related growth factors in rat tendon and skeletal muscle in response to specific contraction types. J Physiol. 2007;582:1303–16. https://doi.org/10.1113/jphysiol.2007.127639.
CAS Article PubMed PubMed Central Google Scholar
Malliaras P, Kamal B, Nowell A, Farley T, Dhamu H, Simpson V, Morrissey D, Langberg H, Maffulli N, Reeves ND. Patellar Tendon adaptation in relation to load-intensity and contraction type. J Biomech. 2013;46:1893–9. https://doi.org/10.1016/j.jbiomech.2013.04.022.
Eriksen, C.S.; Svensson, R.B.; Gylling, A.T.; Couppé, C.; Magnusson, S.P.; Kjaer, M. Load magnitude affects patellar tendon mechanical properties but not collagen or collagen cross-linking after long-term strength training in older adults. BMC Geriatr 2019, 19. https://doi.org/10.1186/s12877-019-1043-0.
Franchi Mv, Atherton PJ, Reeves ND, Flück M, Williams J, Mitchell WK, Selby A, Beltran Valls RM, Narici Mv. Architectural, functional and molecular responses to concentric and eccentric loading in human skeletal muscle. Acta Physiol (Oxf). 2014;210:642–54. https://doi.org/10.1111/apha.12225.
Quinlan JI, Franchi MV, Gharahdaghi N, Badiali F, Francis S, Hale A, Phillips BE, Szewczyk N, Greenhaff PL, Smith K, et al. Muscle and tendon adaptations to moderate load eccentric vs. concentric resistance exercise in young and older males. Gerosci. 2021;43:567–1584. https://doi.org/10.1007/s11357-021-00396-0.
Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative CT method. Nat Protoc. 2008;3:1101–8. https://doi.org/10.1038/nprot.2008.73.
CAS Article PubMed Google Scholar
Babraj, JA.; Cuthbertson, D.J.R.; Smith, K.; Langberg, H.; Miller, B.; Krogsgaard, M.R.; Kjaer, M.; Rennie, M.J. Collagen synthesis in human musculoskeletal tissues and skin. Am J Physiol - Endocrinol Metab 2005, 289. https://doi.org/10.1152/ajpendo.00243.2005.
Brook MS, Wilkinson DJ, Mitchell WK, Lund JN, Phillips BE, Szewczyk NJ, Greenhaff PL, Smith K, Atherton PJ. Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans. J Physiol. 2016;594:7399–417. https://doi.org/10.1113/JP272857.
CAS Article PubMed PubMed Central Google Scholar
Reeves ND, Maganaris CN, Narici Mv. Effect of strength training on human patella tendon mechanical properties of older individuals. J Physiol. 2003;548:971–81.
Mackey AL, Heinemeier KM, Koskinen SOA, Kjaer M. Dynamic adaptation of tendon and muscle connective tissue to mechanical loading. Connect Tissue Res. 2008;49:165–8. https://doi.org/10.1080/03008200802151672.
CAS Article PubMed Google Scholar
Gjaltema RAF, Bank RA. Molecular insights into prolyl and lysyl hydroxylation of fibrillar collagens in health and disease. Crit Rev Biochem Mol Biol. 2017;52:74–95.
Rappu P, Salo AM, Myllyharju J, Heino J. Role of prolyl hydroxylation in the molecular interactions of collagens. Essays Biochem. 2019;63:325–35.
Miller BF, Olesen JL, Hansen M, Døssing S, Crameri RM, Welling RJ, Langberg H, Flyvbjerg A, Kjaer M, Babraj JA, et al. Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise. J Physiol. 2005;567:1021–33. https://doi.org/10.1113/jphysiol.2005.093690.
CAS Article PubMed PubMed Central Google Scholar
Langberg H, Rosendal L, Kjær M. Training-induced changes in peritendinous type I collagen turnover determined by microdialysis in humans. J Physiol. 2001;534:297–302. https://doi.org/10.1111/j.1469-7793.2001.00297.x.
CAS Article PubMed PubMed Central Google Scholar
Franchi, M. v.; Wilkinson, D.J.; Quinlan, J.I.; Mitchell, W.K.; Lund, J.N.; Williams, J.P.; Reeves, N.D.; Smith, K.; Atherton, P.J.; Narici, M. v. Early structural remodeling and deuterium oxide-derived protein metabolic responses to eccentric and concentric loading in human skeletal muscle. Physiol Rep 2015, 3. https://doi.org/10.14814/phy2.12593.
Franchi, M. v.; Ruoss, S.; Valdivieso, P.; Mitchell, K.W.; Smith, K.; Atherton, P.J.; Narici, M. v.; Flück, M. Regional regulation of focal adhesion kinase after concentric and eccentric loading is related to remodelling of human skeletal muscle. Acta Physiola 2018, 223. https://doi.org/10.1111/apha.13056.
Robbins JR, Evanko SP, Vogel KG. Mechanical loading and TGF-β regulate proteoglycan synthesis in tendon. Arch Biochem Biophys. 1997;342:203–11. https://doi.org/10.1006/abbi.1997.0102.
CAS Article PubMed Google Scholar
Vailas AC, Pedrini VA, Pedrini-Mille A, Holloszy JO. Patellar tendon matrix changes associated with aging and voluntary exercise. J Appl Physiol. 1985;58:1572–6. https://doi.org/10.1152/jappl.1985.58.5.1572.
CAS Article PubMed Google Scholar
Koskinen SOA, Heinemeier KM, Olesen JL, Langberg H, Kjaer M. Physical exercise can influence local levels of matrix metalloproteinases and their inhibitors in tendon-related connective tissue. J Appl Physiol. 2004;96:861–4. https://doi.org/10.1152/japplphysiol.00489.2003.
CAS Article PubMed Google Scholar
Tsuzaki M, Bynum D, Almekinders L, Yang X, Faber J, Banes AJ. ATP Modulates load-inducible IL-1β, COX 2, and MMP-3 gene expression in human tendon cells. J Cell Biochem. 2003;89:556–62. https://doi.org/10.1002/jcb.10534.
CAS Article PubMed Google Scholar
Seynnes OR, Erskine RM, Maganaris CN, Longo S, Simoneau EM, Grosset JF, Narici Mv. Training-induced changes in structural and mechanical properties of the patellar tendon are related to muscle hypertrophy but not to strength gains. J Appl Physiol. 2009;107:523–30. https://doi.org/10.1152/japplphysiol.00213.2009.
CAS Article PubMed Google Scholar
Kongsgaard M, Reitelseder S, Pedersen TG, Holm L, Aagaard P, Kjaer M, Magnusson SP. Region specific patellar tendon hypertrophy in humans following resistance training. Acta Physiol. 2007;191:111–21. https://doi.org/10.1111/j.1748-1716.2007.01714.x.
Wang JHC, Guo Q, Li B. Tendon biomechanics and mechanobiology - a minireview of basic concepts and recent advancements. J Hand Ther. 2012;25:133–41. https://doi.org/10.1016/j.jht.2011.07.004.
CAS Article PubMed Google Scholar
Vogel KG. What happens when tendons bend and twist? Proteoglycans J Musculoskelet Neuronal Interact. 2004;4:202–3.
Stenroth L, Peltonen J, Cronin NJ, Sipilä S, Finni T. Age-related differences in achilles tendon properties and triceps surae muscle architecture in vivo. J Appl Physiol. 2012;113:1537–44. https://doi.org/10.1152/japplphysiol.00782.2012.
Couppé C, Svensson RB, Grosset JF, Kovanen V, Nielsen RH, Olsen MR, Larsen JO, Praet SFE, Skovgaard D, Hansen M et al (2014) Life-long endurance running is associated with reduced glycation and mechanical stress in connective tissue. Age (Omaha) 36. https://doi.org/10.1007/s11357-014-9665-9.
Zhou H, Wang SP, Herath K, Kasumov T, Sadygov RG, Previs SF, Kelley DE (2015) Tracer-based estimates of protein flux in cases of incomplete product renewal: evidence and implications of heterogeneity in collagen turnover. Am J Physiol Endocrinol Metab 309. https://doi.org/10.1152/ajpendo.00435.2014.
Abbott CB, Lawrence MM, Kobak KA, Lopes EBP, Peelor FF, Donald EJ, Van Remmen H, Griffin TM, Miller BF (2021) A novel stable isotope approach demonstrates surprising degree of age-related decline in skeletal muscle collagen proteostasis. Function 2. https://doi.org/10.1093/function/zqab028.
Busch R, Kim YK, Neese RA, Schade-Serin V. Collins M, Awada M, Gardner JL, Beysen C, Marino ME, Misell LM et al (2006) Measurement of protein turnover rates by heavy water labeling of nonessential amino acids. Biochimica et Biophysica Acta - General Subjects 1760. https://doi.org/10.1016/j.bbagen.2005.12.023.
Heinemeier KM, Schjerling P, Heinemeier J, Magnusson SP, Kjaer M. Lack of tissue renewal in human adult Achilles tendon is revealed by nuclear bomb 14C. FASEB J. 2013;27:2074–9. https://doi.org/10.1096/fj.12-225599.
留言 (0)