Profile Matching for the Generalization and Personalization of Causal Inferences

From the aDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA

bDepartment of Health Care Policy, Biostatistics, and Statistics, Harvard University, Boston, MA.

Submitted May 20, 2021; accepted May 30, 2022

This work was supported through a Patient-Centered Outcomes Research Institute (PCORI) Project Program Award (ME-2019C1-16172) and grants from the Alfred P. Sloan Foundation (G-2018-10118, G-2020-13946).

The authors report no conflicts of interest.

In the eAppendix; https://links.lww.com/EDE/B945, we provide R code to implement the methods presented in the article. The associated R package can be downloaded from CRAN. This article includes simulated data with code that is available at https://github.com/ericcohn/Profilematching. This article also uses publicly available data.

Supplemental digital content is available through direct URL citations in the HTML and PDF versions of this article (www.epidem.com).

Correspondence: José R. Zubizarreta, Harvard University, 180 A Longwood Avenue, Office 307-D, Boston, MA 02115. E-mail: [email protected].

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