Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock

1 Touro College of Osteopathic Medicine, New York, NY.

2 Department of Pediatrics, University of Utah, Salt Lake City, UT.

3 Department of Pediatrics, Children’s Hospital of Michigan, Detroit, MI.

4 Department of Pediatrics, Central Michigan University, Mt. Pleasant, MI.

5 Department of Anesthesiology and Critical Care Medicine, Children’s Hospital of Philadelphia, Philadelphia, PA.

6 Department of Pediatrics, Children’s Hospital of Los Angeles, Los Angeles, CA.

7 Department of Pediatrics, Nationwide Children’s Hospital, Columbus, OH.

8 Department of Pediatrics, CS Mott Children’s Hospital, University of Michigan, Ann Arbor, MI.

9 Department of Pediatrics, Mattel Children’s Hospital, University of California Los Angeles, Los Angeles, CA.

10 Department of Critical Care Medicine, Children’s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA.

11 Department of Pediatrics, Benioff Children’s Hospital, University of California, San Francisco, San Francisco, CA.

12 Department of Pediatrics, Arkansas Children’s Research Institute, Little Rock, AR.

13 Department of Landscape Architecture and Urban Planning, Texas A&M University, College Station, TX.

14 Division of Pediatric Critical Care Medicine, Department of Pediatrics, Seattle Children’s Hospital, Seattle Children’s Research Institute, University of Washington School of Medicine, Seattle, WA.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (http://journals.lww.com/pccmjournal).

Supported, in part, by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, R01HD073362, for Life After Pediatric Sepsis Evaluation, and was supported, in part, by the following cooperative agreements: UG1HD050096, UG1HD049981, UG1HD049983, UG1HD063108, UG1HD083171, UG1HD083166, UG1HD083170, U10HD050012, U10HD063106, and U01HD049934. Dr. Reeder is supported by R03HD104001 for secondary analyses of the LAPSE database.

No performance site investigators disclose financial interests, activities, relationships, or affiliations that could be construed as real or potential conflicts of interest related to the article or the related investigation. Dr. Varni holds the copyright and the trademark for the Pediatric Quality of Life Inventory (PedsQL) and receives financial compensation from the Mapi Research Trust, which is a nonprofit research institute that charges distribution fees to for-profit companies that use the PedsQL. Dr Varni provided consultation on original study design and final article edits, but he played no role in data acquisition or analysis. Drs. Salud’s, Banks’, Carcillo’s, and Zimmerman’s institutions received funding from the National Institute of Child Health and Human Development. Drs. Salud, Reeder, Banks, Meert, Berg, Zuppa, Newth, Hall, Sapru, Carcillo, McQuillen, Mourani, Varni, and Zimmerman received support for article research from the National Institutes of Health (NIH). Drs. Reeder’s, Meert’s, Berg’s, Zuppa’s, Hall’s, McQuillen’s, Mourani’s, and Varni’s institutions received funding from the NIH. Dr. Banks disclosed government work. Dr. Newth received funding from Philips Research North America, Hamilton Medical, and Nihon Kohden. Dr. Hall received funding from Abbvie, La Jolla Pharmaceuticals, and Kiadis. Dr. Carcillo’s institution received funding from the National Institute of General Medical Sciences. Dr. Zimmerman’s institution received funding Immunexpress; he received funding from Elsevier Publishing. Dr. Quasney has disclosed that he does not have any potential conflicts of interest.

For information regarding this article, E-mail: [email protected]

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